TY - JOUR TT - Primary Progressive Aphasia in Turkish: A Case Study AU - Karalı, Fenise Selin AU - Ünsal, Elif Meryem AU - Savaş, Merve AU - Maviş, İlknur PY - 2018 DA - December JF - Dil Konuşma ve Yutma Araştırmaları Dergisi JO - DKYAD PB - Dil ve Konuşma Terapistleri Derneği WT - DergiPark SN - 2651-2548 SP - 179 EP - 196 VL - 1 IS - 3 KW - primer progresif afazi KW - demans KW - dil KW - biliş KW - günlük yaşam aktiviteleri N2 - Purpose: Primary Progressive Aphasia (PPA) is a neurological syndrome in which language abilities are slowly and gradually impaired. This study aims to determine and describe the language abilities, neuropsychological profile and daily living activities performance of a Turkish speaking person with PPA. Method: In order to assess language, ‘Language Assessment Test for Aphasia’ (ADD); to evaluate neuropsychological abilities Judgement of Line Orientation Test, Benton Face Recognition Test, Clock Drawing Test, Trail Making Test, Simultanagnosia Test, Password Test, 3 Words 3 Shapes Test, Copying item of the Standardized Mini Mental Test; to examine motor abilities Edinburgh Handedness Inventory, Constructional Apraxia Test, Oral Apraxia Test, Diadochokinesis Test, Luria’s Three-step Motor Test; to assess daily living participation Daily Living Activities Scale, Neuropsychiatric Inventory, Frontal behavioral Inventory, Social Network Index Scale and Caregiver Burden Scale have been administered. Results: Regarding Aphasia Language Assessment Test, patient’s speech fluency, auditory comprehension, automatic speech, repetition, naming, reading and writing abilities are severely affected. In addition to decline in the patient’s language disorders, memory, attention and reasoning abilities are also affected and he has coexisting speech apraxia and orobuccal apraxia. Daily living activities are also negatively affected and it was determined that there is a significant decline in self-dependence. Conclusion: Language, cognition and daily activities are affected in primary progressive aphasia. Interventions should be established by considering these areas CR - Akça-Kalem, Ş., Hanağası, H., Cummings, J. L. ve Gürvit, H. (2005). Validation study of the Turkish translation of the neuropsychiatric inventory (NPI). 21st international conference of alzheimer’s disease international, Sept. 28-Oct. 1, 2005 İstanbul, Turkey. Abstract Book Poster 47. CR - Akça-Kalem, Ş., Hanağası, H., Kertesz, A., ve Gürvit, H. (2005). Validation study of the turkish translation of the frontal behavioral inventory (FBI). 21st International Conference of Alzheimer’s Disease International, Sept. 28-Oct. 1, 2005 Istanbul, Turkey. Abstract Book P48, 58–59. CR - Benton, A. L. (1980). The neuropsychology of facial recognition. American Psychologist, 35(2), 176. CR - Benton, A. L., Varney, N. R. ve des Hamsher, K. (1978). Visuospatial judgment: A clinical test. Archives of Neurology, 35(6), 364-367. CR - Keskinkılıç, C. (2008). Standardization of benton face recognition test in a turkish normal adult population. Turkish Journal of Neurology, 14(3), 179-190. CR - Cangöz, B., Karakoç, E. ve Selekler, K. (2006). The norm determination and validity-reliability studies of clock drawing test on Turkish adults and elderlys (ages 50 and over). Turkish Journal of Geriatrics, 9(3), 136- 142. CR - Cangöz, B., Karakoç, E. ve Selekler, K. (2007). İz sürme testinin 50 yaş üzeri Türk yetişkin ve yaşlı örneklemi için standardizasyon çalışması. Türk Geriatri Dergisi, 10, 73-82. CR - Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A. ve Gronbein, J. (1994). The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia. Neurology, 44(12), 2308–2314. CR - Duffy, J. R.., Strand, E. A. ve Josephs, K. A. (2014). Motor speech disorders associated with primary progressive aphasia. Aphasiology, 28, 1004-1017. CR - Henry, M. L. ve Grasso, S. M. (2018). Assessment of individuals with primary progressive aphasia. Seminars in Speech and Language, 39(3), 231–241. doi:10.1055/s-0038-1660782. CR - İnce, A. (2008). ADCS-ADL ölçeğinin türk toplumuna uyarlanması ve geçerlilik-güvenilirliği (Tıpta Uzmanlık tezi). Celal Bayar Üniversitesi Tıp Fakültesi, Manisa. CR - Kaplan, E. (1983). The assessment of aphasia and related disorders (Vol. 2). Lippincott Williams & Wilkins. CR - Kertesz, A., Davidson, W., ve Fox, H. (1997). Frontal behavioral inventory: diagnostic criteria for frontal lobe dementia: Canadian Journal of Neurological Sciences, 29–36. CR - Küçükgüçlü, Ö., Esen A. ve Yener G., (2009). Bakımverenlerin yükü envanterinin Türk toplumu için geçerlik ve güvenirliğinin incelenmesi. Journal of Neurological Sciences, 26(1), 60-73 http://www.jns.dergisi.org/text.php3?id=269 CR - Maviş, İ. ve Toğram, B. (2009). Afazi dil değerlendirme testi. Ankara: Detay Yayıncılık. CR - Maviş, İ. ve Toğram, B. (2012). Validity, reliability and standardization study of the language assessment test for aphasia. Turkish Journal of Neurology, 18(3), 96-103, DOI: 10.4274/Tnd.16779. CR - Mesulam, M. (1990). Essentials of primary progressive aphasia. Turkish Journal of Neurology, 13(1), 52-67. CR - Mesulam, M. M. (1982). Slowly progressive aphasia without generalized dementia. Annals of Neurology, 11, 592– 598. CR - Mesulam, M. M. (1985). Verbal and nonverbal cancellation tests. Principles of behavioral neurology içinde (s. 102-103). Philadelphia, F.A. Davis Co. CR - Mesulam, M. M. (2001). Essentials of primary progressive aphasia. Annals of Neurology, 49, 425–432. CR - Mesulam, M. M. (2003). Primary progressive aphasia – a language-based dementia. New England Journal of Medicine, 349, 1535–1542. CR - Mesulam, M. M. ve Weintraub, S. (1992). Spectrum of primary progressive aphasia. Bailliere's Clinical Neurology, 1, 583–609. CR - Moore, W. M., Rosenbek, J. C. ve LaPointe, L. L. (1976). Assessment of oral apraxia in brain-injured adults. In Clinical Aphasiology: Proceedings of the Conference 1976 (s. 64-79). BRK Publishers. CR - Navon, D. (1977). Forest before trees: The precedence of global features in visual perception. Cognitive Psychology, 9(3), 353-383. CR - Oldfield, R. C. (1971). The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia, 9, 97–113. CR - Reitan, R. M. (1955). The relation of the trail making test to organic brain damage. Journal of Consulting Psychology, 19(5), 393. CR - Simmons-Mackie, N., Raymer, A., Armstong, E., Holland, A. ve Cherney, L. R. (2010). Communication partner training in aphasia: A systematic review. Archives of Physical Medicine and Rehabilitation. 91(12), 1814- 1837. CR - Weintraub, S. ve Rubin, N, P. ve Mesulam, M, M. (1990). Primary progressive aphasia. Longitudinal course, neuropsychological profile, and language features. Archives of Neurology, 47, 1329-1335. CR - Weintraub, S., Peavy, G. M., O'Connor, M., Johnson, N. A., Acar, D., Sweeney, J. ve Janssen, I. (2000). Three words three shapes: a clinical test of memory. Journal of Clinical and Experimental Neuropsychology, 22(2), 267-278. UR - https://dergipark.org.tr/tr/pub/dkyad/issue//557211 L1 - https://dergipark.org.tr/tr/download/article-file/700872 ER -