TY - JOUR T1 - Hemodiyaliz Hastalarında Serebrovasküler Olaylar AU - Özelsancak, Rüya PY - 2020 DA - March Y2 - 2019 DO - 10.17827/aktd.558269 JF - Arşiv Kaynak Tarama Dergisi JO - aktd PB - Çukurova Üniversitesi WT - DergiPark SN - 1300-3755 SP - 1 EP - 7 VL - 29 IS - 1 LA - tr AB - İnme dünya çapında morbidite vemortalitenin önde gelen nedenlerinden biridir. İskemik ve hemorajik olarak iki grubaayrılır ve diyabet, hipertansiyon, sigara ve obezite gibi kardiyovasküler hastalıklarile benzer risk faktörlerine sahiptir. Kronik böbrek hastalığı da sıklığıher geçen gün artan ve geleneksel risk faktörleri dışında, üremik toksinler, anemi,trombosit disfonksiyonu, hipervolemi, malnütriyon-inflamasyon, artmış oksidatifstres gibi kendine has risk faktörleri olan bir hastalıktır. Diyalize girenhasta sayısı ülkemizde her yıl %10oranında artmaktadır ve bu hasta grubunda inme, kronik böbrek hastalığının tümaşamalarında genel populasyona göre 2-10 kat fazla görülmektedir. Bu derlemede,inmenin risk faktörleri ve alt tipleri dahil olmak üzere kronik böbrekhastaları ve diyaliz hastalarında inmeye genel bir bakış sunulmaktadır. KW - hemodiyaliz KW - inme KW - kronik böbrek hastalığı KW - serebral iskemi CR - 1.Donnan GA, Fisher M, Macleod M, Davis SM. Stroke. Lancet. 2008:10;371(9624):1612-23. CR - 2.Feigin VL, Lawes CM, Bennett DA, Barker-Collo SL, Parag V. Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review. Lancet Neurol. 2009;8(4):355-69. CR - 3.O'Donnell MJ, Xavier D, Liu L, Zhang H, Chin SL, Rao-Melacini P, et.al; INTERSTROKE investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet. 2010;376(9735):112-23. CR - 4.Wilson PW, Bozeman SR, Burton TM, Hoaglin DC, Ben-Joseph R, Pashos CL.Prediction of first events of coronary heart disease and stroke withconsideration of adiposity. Circulation. 2008;118(2):124-30. CR - 5.Power A. Stroke in dialysis and chronic kidney disease. Blood Purif.2013;36(3-4):179-83. CR - 6.National Nephrology, Dialysis and Transplantation Registry Report of Turkey 20177.Seliger SL, Gillen DL, Longstreth WT Jr, Kestenbaum B, Stehman-Breen CO.Elevated risk of stroke among patients with end-stage renal disease. Kidney Int. 2003;64(2):603-9. CR - 8.Wang HH, Hung SY, Sung JM, Hung KY, Wang JD. Risk of stroke in long-termdialysis patients compared with the general population. Am J Kidney Dis. 2014;63(4):604-11. CR - 9.Seliger SL, Weiner DE. Cognitive impairment in dialysis patients: focus on the blood vessels? Am J Kidney Dis. 2013;61(2):187-90. CR - 10.Cherng Y-G, Lin C-S, Shih C-C, Hsu Y-H, Yeh C-C, Hu C-J, et al. (2018) Stroke risk and outcomes in patients with chronic kidney disease or end-stage renal disease: Two nationwide studies. PLoS ONE 13(1): e0191155. https://doi.org/10.1371/journal.pone.019115511.Lee M, Saver JL, Chang KH, Liao HW, Chang SC, Ovbiagele B. Low glomerular filtration rate and risk of stroke: meta-analysis. BMJ. 2010;341:c4249.doi: 10.1136/bmj.c4249. CR - 12.Weiner DE, Tabatabai S, Tighiouart H, Elsayed E, Bansal N, Griffith J, et al. Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease. Am J KidneyDis. 2006;48(3):392-401. CR - 13.Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, et al. The relationship between nontraditional risk factors and outcomes in individuals with stage 3 to 4 CKD. Am J Kidney Dis. 2008;51(2):212-23. CR - 14.Ninomiya T, Perkovic V, Verdon C, Barzi F, Cass A, Gallagher M, et al. Proteinuria and stroke: a meta-analysis of cohort studies. Am J Kidney Dis. 2009;53(3):417-25 CR - 15.Lee M, Saver JL, Chang KH, Liao HW, Chang SC, Ovbiagele B. Impact ofmicroalbuminuria on incident stroke: a meta-analysis. Stroke. 2010;41(11):2625-31. CR - 16.Sozio SM, Armstrong PA, Coresh J, Jaar BG, Fink NE, Plantinga LC, et al. Cerebrovascular disease incidence, characteristics, and outcomes in patients initiating dialysis: the choices for healthy outcomes in caring for ESRD (CHOICE) study. Am J Kidney Dis. 2009;54(3):468-77. CR - 17.Toyoda K, Ninomiya T. Stroke and cerebrovascular diseases in patients with chronic kidney disease. Lancet Neurol. 2014;13(8):823-33. CR - 18.Murray AM, Seliger S, Lakshminarayan K, Herzog CA, Solid CA. Incidence of stroke before and after dialysis initiation in older patients. J Am Soc Nephrol. 2013;24(7):1166-73. CR - 19.Toyoda K, Fujii K, Fujimi S, Kumai Y, Tsuchimochi H, et al.Stroke in patients on maintenance hemodialysis: a 22-year single-center study. Am J Kidney Dis. 2005;45(6):1058-66. CR - 20.Lee JG, Lee KB, Jang IM, Roh H, Ahn MY, Woo HY, et al. Low glomerularfiltration rate increases hemorrhagic transformation in acute ischemic stroke.Cerebrovasc Dis. 2013;35(1):53-9. CR - 21.Power A, Chan K, Singh SK, Taube D, Duncan N. Appraising stroke risk inmaintenance hemodialysis patients: a large single-center cohort study. Am JKidney Dis. 2012;59(2):249-57. CR - 22.Onoyama K, Kumagai H, Miishima T, Tsuruda H, Tomooka S, Motomura K, et al Incidence of strokes and its prognosis in patients on maintenance hemodialysis. Jpn Heart J. 1986;27(5):685-91. UR - https://doi.org/10.17827/aktd.558269 L1 - https://dergipark.org.tr/tr/download/article-file/1018087 ER -