TY  - JOUR
TT  - Evaluation of the Clinical Characteristics of the Girls with Central Precocious Puberty at Diagnosis and During Treatment
AU  - Kara, Özlem
PY  - 2019
DA  - September
DO  - 10.12956/tchd.581289
JF  - Türkiye Çocuk Hastalıkları Dergisi
JO  - Türkiye Çocuk Hast Derg
PB  - T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi
WT  - DergiPark
SN  - 1307-4490
SP  - 358
EP  - 362
VL  - 13
IS  - 5
LA  - en
KW  - Awareness
KW  - idiopathic
KW  - menarche
KW  - obesity
KW  - precocious puberty
N2  - Aim: It is aimed to evaluatethe anthropometric and clinical characteristics of the girls with idiopathiccentral precocius puberty (CPP) at diagnosis, during and at the end oftreatment. Materials and methods: Sixty-one girls who were diagnosed with CPP andtreated between January 2015 and December 2018 were included in the study. Theanthropometric, clinical characteristics and laboratory test results atdiagnosis, during and at the end of treatment were retrospectively evaluated. Results: Mean age of the patients at diagnosis was 8.7±0.6 years,bone age was 10.3±1.3 years, target height was 158.4±5.2 cm and predictedheight was 160.1±7.6 cm. While 18 (30%) patients presented with isolatedthelarche, 11 (18%) patients presented with menarche. At diagnosis, 28% of thepatients were obese and 25% were overweight. The average treatment period was 2years. The body mass index (BMI) increased during treatment (p<0.001) whichwas significant especially in the first two years of treatment (p<0.001). Infirst year of treatment, the ratio of the obese patients had increased to 36%.During treatment, height growth rates were decreased (p=0.02). However, thepredicted height at the end of the study was 160.1±6.2 cm and there was nodifference when compared to the height at diagnosis (p>0.05).Conclusion: Obese and overweight girls should be followed up forpubertal development. Awareness level of primary care physicians andpediatricians should be increased in order to identify the early pubertyfindings and provide appropriate guidance.
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UR  - https://doi.org/10.12956/tchd.581289
L1  - http://dergipark.org.tr/tr/download/article-file/809712
ER  -