TY - JOUR T1 - A cross‐sectional study: Is there any effects of cholesterol ratios on acute ischemic stroke severity? TT - Kesitsel bir araştırma: Kolesterol oranlarının akut iskemik inme şiddeti üzerine etkisi var mı? AU - Ünsal, Miraç Ayşen AU - Öztürk, Bilgin PY - 2019 DA - December DO - 10.18663/tjcl.588068 JF - Turkish Journal of Clinics and Laboratory JO - TJCL PB - DNT Ortadoğu Yayıncılık A.Ş. WT - DergiPark SN - 2149-8296 SP - 437 EP - 439 VL - 10 IS - 4 LA - en AB - Aim: Theaim of prevention of stroke and stroke related complications is to control andeliminate modifiable risk factors. Since hypercholesterolemia is one of theserisk factors, we aimed to compare the low density lipoprotein cholesterol(LDL-C) / high density lipoprotein cholesterol (HDL-C) and total cholesterol /HDL-C ratios with NIHSS scores and to evaluate the effects of these ratios onthe severity of stroke.Materialand Methods:This retrospective cross-sectionalstudy included 207 patients with ischemic stroke. Demographic characteristics,total cholesterol, triglycerides, LDL-C and HDL-C levels of patients who didnot use any lipid-lowering drug and NIHSS scores were recorded in a datacollection form.Theeffects of LDL-C / HDL-C and total cholesterol / HDL-C ratios on NIHSS scoreswere investigated.Results:The mean age of the patientswas 69.3 years. The mean LDL-C / HDL-C ratio was 2.93 and the total cholesterol/ HDL-C ratio was 4.68. The mean score of NIHSS was 7.05 at admission. No statisticallysignificant difference or correlation was observed between all theseparameters.Conclusion:Therewas no statistically significant relationship between HDL-C / LDL-C and totalcholesterol / HDL-C ratios and NIHSS scores. Considering the risk of ischemicstroke, prospective multicentric studies are needed to find proper parameters. KW - ischemic stroke KW - HDL-C KW - LDL-C N2 - Amaç:İnmeve inme ile ilgili komplikasyonların önlenmesinin amacı, değiştirilebilir riskfaktörlerini kontrol etmek ve ortadan kaldırmaktır. Hiperkolesterolemi bu riskfaktörlerinden biri olduğundan, düşük dansiteli lipoprotein kolesterol (LDL-C)/ yüksek dansiteli lipoprotein kolesterol (HDL-C) ve total kolesterol / HDL-Coranları ile NIHSS puanlarını karşılaştırarak, bu oranların inme ciddiyetineetkilerini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Buretrospektif kesitsel araştırma iskemik inmeli 207 hastayı içermektedir.Hastaların demografik özellikleri, total kolesterol, trigliserit, herhangi birlipid düşürücü ilaç kullanmayan hastaların LDL-C ve HDL-C düzeyleri ve NIHSSskorları bir veri toplama formunda kaydedildi. LDL-C / HDL-C ve totalkolesterol / HDL-C oranlarının NIHSS puanlarına etkisi araştırıldı.Bulgular:Hastalarınyaş ortalaması 69.3 idi. 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