@article{article_592398, title={Rare Disease and Orphan Drug Situations in Turkey and around the World}, journal={Aurum Journal of Health Sciences}, volume={1}, pages={95–109}, year={2019}, author={Aksu, Buket}, keywords={Rare,disease,orphan,drug}, abstract={<div>Abstract: Diseases with a prevalence less than 1/2000 are defined as “Rare Diseases”. This group of diseases is a highly </div> <div>heterogeneous group that affects multiple systems. Approximately 80% of these are caused by genetic reasons, and </div> <div>the remaining 20% are caused by environmental factors or are idiopathic. Orphan drug is defined as a medicinal </div> <div>product designed for a life-threatening or chronically impairing rate disease but with a low possibility of obtaining a </div> <div>return on investment due to insufficient sales. In Turkey, where consanguineous marriage frequency is 25% on average, </div> <div>the probability of rare diseases is quite high. Lack of knowledge and specialist physicians, very expensive treatments, </div> <div>and lack of a designated regulation for rare diseases and orphan drugs are the main problems in our country. The </div> <div>research revealed that orphan drugs were imported to Turkey through the Turkish Pharmacists’ Association (TEB) </div> <div>and not covered by Social Security, therefore making it hard for the patients with low income to reach these drugs. </div>}, number={2}, publisher={Altınbaş Üniversitesi}