TY - JOUR T1 - The relationship between myocardial viability and plasma NT-proBNP levels AU - Keskin, Kudret PY - 2019 DA - September Y2 - 2019 JF - Journal of Human Rhythm PB - Ramazan AKDEMİR WT - DergiPark SN - 2149-455X SP - 246 EP - 255 VL - 5 IS - 3 LA - en AB - Aim: There is no biochemical markerthat indicates myocardial viability in the late phase after myocardialinfarction. The aim of our study was to identify whether plasma NT-proBNPlevels indicate the presence of viable myocardium after myocardial infarction.Material and Methods: Patients withmyocardial infarction and left ventricular ejection fraction of less than 45%were included in the study. Exercise or pharmacological myocardial perfusionscintigraphy was performed to investigate viability in the infarction region.The left ventricle was divided into 19 segments where the necrotic area andviable myocardium within it was measured. Blood samples for NT-proBNPmeasurement were obtained from all patients on the same day scintigraphyperformed.Results: A total of 60 patientswere included in the study (10 females, 50 males, mean age 62 ± 9 years). 48(80%) patients underwent exercise scintigraphy. The mean exercise time was 7.1± 2.3 minutes. The infarct area was located in anterior segments in 16patients, inferior in 25, and in both locations in 19 patients. The mean leftventricular ejection fraction was 36 ± 8%. There was a negative correlationbetween left ventricular ejection fraction and serum NT-proBNP levels (r =-0.03 p <0.01). On the other hand, there was no correlation between plasmaNT-proBNP levels and the presence or extent of viable myocardium within thenecrotic area (P = 0.8).Conclusion: There was no correlation betweenplasma NT-proBNP levels and the presence of viable myocardium in the infarct zonein patients with myocardial infarction KW - myocardial infarction KW - viable myocardium KW - NT-proBNP CR - References CR - 1. Perelshtein Brezinov O, Klempfner R, Zekry S Ben, Goldenberg I, et al. Prognostic value of ejection fraction in patients admitted with acute coronary syndrome: A real world study. Medicine (Baltimore). 2017; 96: e6226. 2. Singh P, Sethi N, Kaur N, Kozman H. Revascularization in Severe Left Ventricular Dysfunction: Does Myocardial Viability Even Matter? Clin Med Insights Cardiol. 2015; 9: 105-109. 3. Yao S-S, Chaudhry FA. Assessment of myocardial viability with dobutamine stress echocardiography in patients with ischemic left ventricular dysfunction. 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