@article{article_608954, title={ANTIBACTERIAL CHARACTERISTICS OF NANOFIBER STRUCTURES OBTAINED BY BENZALKONIUM CHLORIDE ADDITIVE POLY (VINYL ALCOHOL)/GELATIN}, journal={International Journal of Advances in Engineering and Pure Sciences}, volume={31}, pages={122–127}, year={2019}, DOI={10.7240/jeps.608954}, url={https://izlik.org/JA52HZ79EF}, author={Yüksek, Metin and Yolay, Onur and Tezcan, Erdem and İşgören, Erkan and Saltık, Derya and Çalışkan, Fatmagül}, keywords={Elektroeğirme,PolivinilAlkol,PVA,Benzalkonyum Klorür,BAC,Antibakteriyel,Nanolif}, abstract={<p class="MsoNormal" style="margin-bottom:6pt;text-align:justify;"> <span lang="en-us" style="color:#000000;" xml:lang="en-us">Polyvinyl
alcohol (PVA) is a hydrophilous and semi-crystallized. It has attracted much
relevancy due to its pretty chemical endurance, fine thermal determination,
decent physical specialities, wonderful bio-compatibility and cheapness.
Gelatin (G) is a natural polymer and that are interesting materials for
biomedical applications. Electrospinning is a simple method that provides very
porous nanofiber production with high surface area. It is possible to produce
biomedical, filtration, energy storage and protective materials by using
electrospinning method. Benzalkonium chloride (BAC) is a kind of anti-microbial
cationic surface-active agent, which has been pretty used in merchant wound
dressings and has a powerful status toward Gr+ bacteria. </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="margin-top:6pt;margin-right:0cm;margin-bottom:6pt;margin-left:0cm;text-align:justify;"> <span lang="en-us" style="color:#000000;" xml:lang="en-us">In this study, nanofibers were
produced from electrospinning of BAC, PVA and G containing solutions at various
concentrations. The fibers of obtained nanofiber structure were uniform,
continuous and intensive. The optimum parameters in terms of good mechanical
and antibacterial properties were determined. S2 sample, electrospun from </span> <span lang="en-us" xml:lang="en-us">11.63% PVA + 1.0% G +1.0% BAC
containing solution, had the best morphological and mechanical properties due
to having the thinnest fiber diameter (51±13nm) and the highest vertical
strength (4.299MPa) and horizontal strength (4.058MPa). It also had antibacterial
activity against all the bacteria tested ( <i>E. coli,
P. aeruginosa, B. subtilis and S. aureus </i>). Due to owning
good mechanical and antibacterial properties, S2 sample can have many uses in
medical sector. <span style="color:#000000;"> </span> </span> </p> <p> </p>}