@article{article_615059, title={Determination of Median Values of First Trimester Screening Tests: A Tokat Scale Retrospective Study}, journal={Van Sağlık Bilimleri Dergisi}, volume={12}, pages={15–21}, year={2019}, author={Katar, Muzaffer}, keywords={free ß-hCG,PAPP-A,Double screening test}, abstract={<p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Objectives: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
The aim of this study was to determine the ability of maternal serum plasma
protein A (PAPP-A) and free beta-human chorionic gonadotropin (free ß-hCG)
values ​​measured in the first trimester screening test to predict the
complications that may develop in later gestational weeks, calculate the median
values ​​of these parameters and compare them with those of software we use. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Materials and methods: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
The study included 16-46 years old women who applied to biochemistry laboratory
of Tokat Gaziosmanpasa University School of Medicine with gestational ages of 10
weeks and 6 days to 13 weeks and 6 days. The results of 3166 pregnant women were
evaluated retrospectively. </span> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Results: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
The mean age of the patients was 27.43 ± 5.46 and their weight was 65.66 ±
13.13 kilograms. Crown rump lengthes (CRL) were determined as 60.71 ± 8.56 mm.
Free ß-hCG levels were 55.1 ± 132.07 ng / mL and PAPP-A values ​​were 3683.53 ±
2486 mIU / l. Nuchal translucency measurements (NT) were determined as 1.38 ±
0.37mm. PAPP-A and Free ß-hCG MoM values ​​were 1.23 ± 0.68 and 1.23 ± 0.88,
respectively. New median values ​​of β-hCG were found to be significantly lower
than those of the program (p <0.05), while PAPP-A values ​​were
significantly higher (p <0.05). </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">Conclusion: </span> </b> <span style="font-size:12pt;line-height:200%;font-family:’Times New Roman’, serif;">
The accuracy and performance of first trimester screening tests should be
improved. Determination of median values ​​specific to the region and even to
the laboratory is now inevitable </span> </p> <p> </p>}, number={2}, publisher={Van Yüzüncü Yıl Üniversitesi}, organization={There are no institutions supporting our study}