TY - JOUR T1 - Maternal and neonatal outcomes related to iron deficiency anemia and serum ferritin status: A multicenter prospective study from Eastern Marmara, Turkey TT - Demir Eksikliği Anemisi ve Serum Ferritin Düzeyi ile İlgili Maternal ve Neonatal Sonuçlar: Doğu Marmara Bölgesine Ait Çok Merkezli Bir Prospektif Çalışma, Türkiye AU - Pulatoğlu, Çiğdem AU - Başbuğ, Derya AU - Akar, Bertan AU - Şimşek, Hayal AU - Çakır, Pınar AU - Başbuğ, Alper AU - Çalışkan, Eray PY - 2019 DA - December JF - Namık Kemal Tıp Dergisi JO - NKMJ PB - Tekirdağ Namık Kemal Üniversitesi WT - DergiPark SN - 2587-0262 SP - 228 EP - 235 VL - 7 IS - 3 LA - en AB - Background:Irondeficiency is the most common nutritional deficit in the world. More than 50%of anemia in pregnancy results from iron deficiency and it is suggested that itmay be associated with negative pregnancy outcomes. Aim:Theaim of this study was to evaluate the incidence of irony deficiency anemia inpregnancy in the East Marmara region of Turkey in order to determine itsprevalence in the country along with the effects and associations of ironsupplementation or iron status on maternal and neonatal outcomes. Study Design: The study was designed as a prospective, longitudinal qualitative study.Method:This study was conducted in six centers in three provinces of the East Marmararegion(Turkey) and included a total of 1102 pregnant women. Blood samples werecollected for hematological status and serum ferritin levels during pregnancy,and the adverse maternal and perinatal outcomes were determined.Results:The rate of anemia among the women included in the study was 19.8%, with 44% ofthem receiving iron supplementation. The maternal age was lower in the anemicgroup(26.5 vs. 27.7, p = 0.01). Selective iron use was more frequent in theanemic group, while routine iron use was more frequent in the non-anemicgroup(47.1% vs. 29.3%; p = 0.01).Conclusions:Iron deficiency anemia is a frequent problem in pregnancy. However, many anemicpregnant women do not receive iron therapy. Iron supplementation may havepositive effects on some maternal and perinatal outcomes. In order to combatiron deficiency anemia in pregnancy, widespread use of iron supplements shouldbe established. KW - Anemia KW - ferritin KW - iron deficiency KW - iron supplementation KW - pregnancy N2 - Amaç:Buçalışmanın amacı, demir takviyesi ve demir durumunun maternal ve neonataletkileri ile birlikte Türkiye'nin Doğu Marmara bölgesinde gebelikte görülendemir eksikliği anemisi insidansını değerlendirmektir.Yöntem:Bu çalışma Doğu Marmara Bölgesi'nin (Türkiye) üç ilinde altı merkezdegerçekleştirilmiş ve toplam 1102 gebeyi kapsamıştır. Gebelik sırasındahematolojik durum ve serum ferritin düzeyleri için kan örnekleri toplandı veolumsuz maternal ve perinatal sonuçlar belirlendi.Bulgular:Çalışmaya dahil edilen kadınlarda anemi oranı % 19.8 idi ve bunların % 44'üdemir desteği alıyordu. Maternal yaş anemik grupta daha düşüktü (26.5'e karşı27.7, p = 0.01). Anemik grupta selektif demir kullanımı daha sık görülürken,anemik olmayan grupta rutin demir kullanımı daha sık görüldü (% 47.1'ekarşılık% 29.3; p = 0.01).Sonuçlar: Demir eksikliği anemisi gebelikte sık görülenbir problemdir. Bununla birlikte, birçok anemik gebeye demir tedavisi verilmez.Demir takviyesi, bazı maternal ve perinatal sonuçlar üzerinde olumlu etkileri olabilir.Gebelikte demir eksikliği anemisiyle mücadele etmek için demir takviyelerininyaygın kullanımı sağlanmalıdır. CR - Stevens GA, Finucane MM, De-Regil LM, Paciorek CJ, Flaxman SR, Branca F et al. 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