TY - JOUR T1 - The effects of capnography during sedation in pediatric esophagogastroduodenoscopy procedures: A randomized controlled study TT - Pediatrik özafagogastroduodenoskopi işlemlerinde sedasyon sırasında kullanılan kapnografinin etkinliği: Randomize kontrollü çalışma AU - Tarıkçı Kılıç, Ebru AU - Gerenli, Nelgin PY - 2019 DA - September DO - 10.17940/endoskopi.632022 JF - Endoskopi Gastrointestinal PB - Türk Gastroenteroloji Vakfı WT - DergiPark SN - 1302-5422 SP - 31 EP - 37 VL - 27 IS - 2 LA - en AB - Background and Aims: Microstreamcapnography monitors are devices that use nasal sample lines to measure pulse oximeterand end-tidal carbon dioxide values of spontaneously breathing patients.Research suggests that capnography is a more sensitive measure of ventilationthan standard modalities. This study aimed to determine whether addingcapnography to standard monitoring improves thedetection of respiratory depression in children undergoing esophagogastroduodenoscopywith sedation before hypoxemia occurs. Materials and Methods: We enrolled 100 children undergoing esophagogastroduodenoscopywith sedation in a pediatric endoscopy department. All children receivedstandard monitoring and capnography and were randomized to study (n = 50; capnography monitor) and control (n = 50; blind to monitor) groups. The primary outcome was an oxygendesaturation rate < 90%. Results: The control group hadhigher rates of hypoventilation and oxygen desaturationper minute and received more interventions than the study group. Untimelyinterventions with hypoventilation were associated with oxygendesaturation < 90%. All episodes of hypoventilation were due to hypopnea;however, medication, gender, and sedation duration were not significantlyassociated with this outcome. Conclusion: Hypoventilation is commonduring sedation of pediatric patients undergoingesophagogastroduodenoscopy. Capnography monitoring provides fewer but timelyinterventions for apnea and hypoventilation and improves the quality of careduring sedation. We, therefore, highly recommend the use of capnographymonitoring. KW - Esophagogastroduodenoscopy procedures KW - end-tidal carbon dioxide KW - capnography KW - hypopnea KW - hypoventilation KW - airway interventions N2 - Girişve Amaç: Mikro-akım kapnografi, spontan soluyan hastalarda nazalhattı ile puls oksimetre, end-tidal karbon dioksit değerlerini izlemek içinkullanılan bir cihazdır. Bugüne kadar ki kanıtlar, kapnografi kullanılmasınınstandart yöntemlerden daha hassas bir ventilasyon ölçümü olduğunugöstermektedir. Çalışmamızda, özofagogastroduodenoskopi yapılan çocuklarınsedasyonu sırasında standart izlemeye kapnografi eklenmesinin hipoksemioluşmadan önce solunum depresyonunu tespit edip etmediğini belirlemeyiamaçladık. Gereç ve Yöntem: Pediatrikendoskopi bölümünde özofagogastroduodenoskopi uygulanan 100 çocuğa sedasyonuygulandı. İşleme alınan tüm çocuklara standart monitörizasyon ve kapnografiuygulandı ve randomizasyon ekibin kapnografi monitörünü (çalışma grubu) görüpgörmemesi veya monitöre (kontrol grubu) kör olup olmaması durumuna göreyapıldı. Birincil sonuç, oksijen desatürasyon oranı <% 90 idi. Bulgular: Randomize olarak her gruba 50kişi dahil edildi. Kontrol grubunda hipoventilasyon ve oksijen desatürasyonoranı daha yüksek bulundu. Havayolu müdahale oranları çalışma grubunda kontrolgrubuna göre daha az bulundu. Hipoventilasyon ile zamanında yapılmayanmüdahaleler oksijen desatürasyonu < 90 ile ilişkilendirildi.Tüm hipoventilasyon atakları hipopneyebağlıydı. İlaç kullanımı, cinsiyet, sedasyon süresi bu sonuçla anlamlı olarakilişkili bulunmadı. Sonuç: Özofagogastroduodenoskopiuygulanan pediatrik hastaların sedasyonu sırasında hipoventilasyon sıktır.Kapnografi kullanımı ise apne ve hipoventilasyon durumunda sayı olarak daha azancak tam zamanında hava yolu müdahalesi sağlayıp, sedasyon sırasındakikaliteyi artırır. Kapnografi kullanılmasını kesinlikle gerekli buluyoruz. CR - 1. Leroy PL, Schipper DM, Knape HJ. Professional skills and competence for safe and effective procedural sedation in children: recommendations based on a systematic review of the literature. Int J Pediatr 2010;934298. CR - 2. Barbi E, Petaros P, Badina L, et al. Deep sedation with propofol for upper gastrointestinal endoscopy in children, administered by specially trained pediatricians: a prospective case series with emphasis on side effects. Endoscopy 2006;38:368-75. CR - 3. Burton JH, Harrah JD, Germann CA, Dillon DC. Does end-tidal carbon dioxide monitoring detect respiratory events prior to current sedation monitoring practices? 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Andolfatto G, Willman E. A prospective case series of pediatric procedural sedation and analgesia in the emergency department using single-syringe ketamine-propofol combination (ketofol). Acad Emerg Med 2010;17:194-201. UR - https://doi.org/10.17940/endoskopi.632022 L1 - https://dergipark.org.tr/tr/download/article-file/831535 ER -