@article{article_635524, title={Serum levels of Pentraxin-3, Vaspin, Apelin and troponin in decompensated heart failure patients}, journal={Turkish Journal of Clinics and Laboratory}, volume={11}, pages={39–46}, year={2020}, DOI={10.18663/tjcl.635524}, author={Kaya, Bedri Caner and Demirbağ, Recep}, keywords={troponin I, vaspin, apelin, pentraxin-3, biobelirteç, dekompanse kalp yetersizliği}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Aim: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">
The aim of the present study is to evaluate the levels of these biomarkers in
decompensated heart failure (HF) patients. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span lang="tr" style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;" xml:lang="tr">Material and Methods: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">44
decompensated HF patients and 32 healthy individuals were enrolled in the study
as patient and control groups. Transthoracic echocardiography and serum
troponin I, vaspin, apelin, and PTX-3 levels besides routine laboratory
analysis were performed for both groups. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Results: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Troponin
I and vaspin were higher, apelin was lower in patient group (for all,
p<0.05).PTX-3 levels were higher in patient group, but it was not
statistically significant (p=0.133). Troponin I and PTX-3 levels were
significantly decreased (for both, p<0.05) with in-hospital-HF treatment. Vaspinand
apelin levels did not show any significant change (p=0.938, p=0.121,
respectively). Vaspin had an independent relationship with troponin, <span>apelin had an independent relationship with PTX-3,
troponin and apelin had independent relationship with vaspin, and finally
troponin,PTX-3, and vaspin had independent relationship with apelin in
decompensated HF patients. </span> </span> </p> <p> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:150%;"> <b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Conclusion: </span> </b> <span style="font-size:12pt;line-height:150%;font-family:’Times New Roman’, serif;">Troponin I and vaspin levels were elevated,and serum apelin
levels were reduced in decompensated HF patients. PTX-3 levels were higher in
HF patients, but it was not statistically significant. Vaspin and apelin levels
did not change with HF stabilization in HF patients, but troponin I and PTX-3
levels were significantly decreased.t </span> </p> <p> </p>}, number={1}, publisher={DNT Ortadoğu Yayıncılık A.Ş.}