@article{article_635691, title={Crystalloid preload versus crystalloid coload during spinal anesthesia for ureterorenoscopy: A randomized controlled trial}, journal={Ege Tıp Dergisi}, volume={59}, pages={181–187}, year={2020}, DOI={10.19161/etd.790402}, url={https://izlik.org/JA92EP22FP}, author={Kılınç, Nurhayat and Deniz, Mustafa Nuri and Erhan, Elvan}, keywords={Spinal anestezi, preload, koload, kristalloid}, abstract={Aim: The optimal strategy of fluid administration during spinal anesthesia is still unclear. In this double-blind randomized study, we assessed the timing of fluid administration for spinal anesthesia in patients undergoing ureterorenoscopy. Materials and Methods: 60 ASA I-III patients scheduled for anesthesia were randomly allocated to receive either 500 ml crystalloid preload (30 minutes before spinal anesthesia) or 500 ml crystalloid coload (at the start of spinal anesthesia). Ephedrine 5 mg boluses were administered when the systolic blood pressure decreased more than 20% of the baseline value. Atropine 0.5 mg was given to the patients whose heart rate decreased bellow 50 beats/minutes. Hemodynamic variables were recorded during the surgery. Results: The groups were compared in terms of demographic data and surgical time and there was no difference between them. In Group II, only 1 patient needed ephedrine, while in Group I, no patient was administered ephedrine. No patients in both groups needed atropine for bradycardia. There was no difference between the groups in terms of the need for ephedrine. Conclusion: Crystalloid preload and crystalloid coload administration do not differ in terms of the need for vasopressor agents in patients undergoing ureterorenoscopy under spinal anesthesia}, number={3}