TY - JOUR T1 - Kayseri Şehir Hastanesi Kardiyoloji Kliniğinde Koroner Arter Hastalığı Olan Hastalarda Lipid Düşürücü İlaç Kullanımına Uyum ve LDL-Kolesterol Hedefine Ulaşma Düzeyleri TT - Compliance with Lipid-Lowering Therapy Use and Achieving LDL-Cholesterol Target Levels in Patients with Coronary Artery Disease in The Cardiology Clinic of Kayseri City Hospital AU - Şahin, Ömer PY - 2020 DA - January DO - 10.31020/mutftd.650069 JF - Mersin Üniversitesi Tıp Fakültesi Lokman Hekim Tıp Tarihi ve Folklorik Tıp Dergisi PB - Mersin Üniversitesi WT - DergiPark SN - 1309-8004 SP - 84 EP - 90 VL - 10 IS - 1 LA - tr AB - Giriş: Aterosklerotik kalp hastalıkları tüm dünyada öndegelen morbidite ve mortalite nedenidir. Aterosklerozun patogenezinebakıldığında, dislipidemiler en yaygın ve düzeltilebilen risk faktörlerindenbiridir. Bu çalışmamızda kardiyoloji kliniğinde takip etmekte olduğumuz koronerarter hastalığı nedeniyle lipid düşürücü tedavi alması gereken hastaların lipiddüşürücü ilaç tedavileri ve lipid düzeylerinin incelenmesi amaçlanmıştır. Yöntem: Aralık 2018 ile Temmuz 2019 arasında kardiyolojikliniğine başvuran daha önce koroner anjiografi ile koroner arter hastalığıdökümante edilmiş hastalar lipid düşürücü ilaç tedavileri yönünden incelendi.Bulgular: Lipid düşürücü ilaç kullanan grupta totalkolesterol ve LDL-kolesterol seviyelerinin anlamlı olarak düşük olduğu tespitedildi (sırasıyla 198.1±40.4 ve 171.6±35.1, p≤0.001, 118,69±36.4 ve 92.2±31.5,p≤0.001). LDL-kolesterol<55 mg/dL hedef değerine ulaşan hastalarıincelediğimizde, lipid düşürücü ilaç kullanmayan grupta bir hastada hedefeulaşılırken, lipid düşürücü tedavi alan grupta 20 hastanın hedefe ulaştığıgözlendi (p=0.023).Sonuç: Çalışmamızda koroner arter hastalığı nedeniyleçok yüksek risk grubunda olan ve ikincil koruma amaçlı lipid düşürücü tedavialması gereken hastaların etkin dozda ilaç kullanmadıkları tespit edildi. Lipiddüşürücü tedavi alan hastalarda kullanılan dozdan bağımsız olarakLDL-kolesterol hedefine ulaşan hasta sayısı düşük bulunmuştur. KW - Koroner arter hastalığı KW - Lipid düşürücü tedavi N2 - Introduction: Atherosclerotic heart disease is theleading cause of morbidity and mortality worldwide.When we look at thepathogenesis of atherosclerosis, dyslipidemias are one of the most common andcorrectable risk factor. In this study, we aimed to investigate lipid-loweringdrug therapies and lipid levels in patients who needed lipid-lowering therapydue to coronary artery disease in cardiology clinic.Method: Patients who were previously documented withcoronary artery disease by coronary angiography between December 2018 and July2019 were examined for lipid-lowering therapy.Result: Total cholesterol and LDL-cholesterol levelswere significantly lower in the lipid lowering group (198.1±40.4 ve 171.6±35.1,p≤0.001, 118,69±36.4 ve 92.2±31.5, p≤0.001, respectively). When we analyzedpatients reaching LDL-cholesterol<55 mg / dL target value, one patient inthe non-lipid lowering group achieved the target, while 20 patients in thelipid lowering group achieved the target (p=0.023). 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