@article{article_687446, title={Pathological features of fetal anasarca in Pekingese puppies}, journal={Journal of Turkish Veterinary Medical Society}, volume={91}, pages={164–168}, year={2020}, DOI={10.33188/vetheder.687446}, author={Monsef, Yanad and Karakaş Alkan, Kübra and Yücel, Gözde and Hazıroğlu, Rıfkı}, keywords={Fötal anasarka,Histopatoloji,Hydrops fetalis,Köpek,Pekingese}, abstract={Fetal anasarca is a congenital condition defined by excessive fluid accumulation throughout the body and subcutaneous edema. A 9-month-old Pekingese bitch with dystocia was presented to the Obstetrics and Gynecology Department of Ankara University, Faculty of Veterinary Medicine. Three stillborn puppies were removed by caesarian section and sent to the Pathology Department of Ankara University, Faculty of Veterinary Medicine for necropsy. Grossly, two of the puppies were larger than normal, had diffuse subcutaneous swelling with visceral effusion and were diagnosed with fetal anasarca. As for the third one, pulmonary hypoplasia was reported. All the fetuses additionally showed palatoschisis, bird tongue and lissencephaly. For histopathological examination, samples from the organs were collected and routinely processed. Severe edematous and degenerative changes were noted in the skin, liver, heart and kidneys of the anasarcous fetuses. Extramedullary hematopoiesis was also observed to different degrees in the livers and the spleens of all fetuses. The current case represents the first histopathologically described case of canine fetal anasarca in Turkey and it highlights the predisposition of brachycephalic dogs to fetal anasarca which is referred to be heritable as a recessive trait.}, number={2}, publisher={Veteriner Hekimler Derneği}