@article{article_687605, title={The Efficacy of Intrathecal Morphine With Bupivacaine For Postoperative Analgesia After TUR-B}, journal={Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi}, volume={7}, pages={65–69}, year={2020}, DOI={10.34087/cbusbed.687605}, author={İncesu, Aylin and Deniz, Mustafa Nuri and Erhan, Elvan and Ugur, Güden}, keywords={Spinal anestezi,morfin,postoperative ağrı,transüretral mesane rezeksiyonu}, abstract={Objective,: In this randomized study, we evaluated two different doses of intrathecal (IT) morphine with bupivacaine for analgesia after transurethral resection of bladder (TUR-B).
Methods: Seventy-five patients were randomly divided into three groups. They were allocated to receive IT morphine (100 µg) with 12.5 mg 0.5% bupivacaine (Group 1), IT morphine (200 µg) with 12.5 mg 0.5% bupivacaine (Group 2), and IT 12.5 mg 0.5% bupivacaine without morphine (Group 3). Postoperative pain was evaluated by VAS during 24 h and each patient was given intravenous paracetamol and Dexketoprophen trometamol if pain severity was moderate. Results: VAS scores were significantly lower in Groups I and II than Group III at 1h, 2h, 4h, 6h, 12h (p< 0.05) (Figure 1). The request for analgesia was significantly higher in Group III than the other two groups (p< 0.05). More patients reported postoperative nausea in Group II than the other two groups (p< 0.05) (Figure 2).
Conclusion: IT morphine (100 µg and 200 µg) with 12.5 mg 0.5% provided a significant reduction in postoperative pain scores compared to IT 12.5 mg 0.5% bupivacaine alone. IT morphine 100 µg provided comparable postoperative pain control with significantly lower side effects than IT morphine 200 µg after TUR-B.}, number={1}, publisher={Manisa Celal Bayar Üniversitesi}, organization={Yok}