@article{article_696747, title={Mean Platelet Volume and Coronary Artery Ectasia}, journal={Sakarya Tıp Dergisi}, volume={10}, pages={225–230}, year={2020}, DOI={10.31832/smj.696747}, author={Zorlu, Çağrı and Köseoğlu, Cemal}, keywords={Anjiyografi,Koroner arter hastalığı,Ortalama trombosit hacmi,Koroner anevrizma,Koroner arter hastalığı}, abstract={<p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;"> </span> </b> </p> <p> <b>  </b> </p> <b> </b> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">Abstract </span> </b> </p> <p> <b> </b> </p> <b> </b> <p class="MsoNormal" style="margin-bottom:.0001pt;text-align:justify;line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">Objective:
C </span> </b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">oronary artery ectasia (CAE) are defined as
the dilation of a segment of a coronary artery at least 1.5 times the adjacent
segment. </span> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;"> Several studies have shown the association between
mean platelet volume (MPV) and cardiovascular diseases. </span> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">But
the results are different. For this
reason, we aimed to investigate the association of MPV with CAE. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">Materials
and Methods: </span> </b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;"> 90 patients with normal
coronary arteries and 70 patients with CAE were included. Routine blood and
biochemical parameters were measured before the arteriography. Differences
between groups for continuous variables were analyzed with t- test or
Mann-Whitney U test. P values < 0.05 were considered significant. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">Results: </span> </b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;"> Baseline patient demographics, including age and
clinical risk factors, were similar between the groups. Compared to the control
group, MPV levels were significantly lower in the CAE group (8.84 ± 1.71fL vs.
10.43 ± 1.34, p < 0.001). MPV level of < 9,5 fL showed sensitivity ,
specificity value of 95%, 80%; </span> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">area under the curve= 0.943, 95% CI, 0.906–0.980) for the
prediction of CAE. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;line-height:200%;"> <b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;">Conclusion: </span> </b> <span style="font-size:10pt;line-height:200%;font-family:Arial, sans-serif;"> The present study suggests that MPV may decrease in
patients with CAE. </span> </p> <p> </p>}, number={2}, publisher={Sakarya Üniversitesi}