TY - JOUR T1 - EFFECTS OF STATIC AND FUNCTIONAL STRETCHING EXERCISES ON LOWER LIMB SPASTICITY AND FUNCTION IN PEOPLE WITH MULTIPLE SCLEROSIS: A RANDOMIZED CONTROLLED TRIAL TT - MULTİPL SKLEROZLU BİREYLERDE STATİK VE FONKSİYONEL GERME EGZERSİZLERİNİN ALT EKSTREMİTE SPASTİSİTESİ VE FONKSİYONU ÜZERİNE ETKİLERİ: RANDOMİZE KONTROLLÜ BİR ÇALIŞMA AU - Nodehi Moghadam, Afsun AU - Ergül, Merziye AU - Bıglarıan, Akbar PY - 2021 DA - December DO - 10.21653/tjpr.762021 JF - Türk Fizyoterapi ve Rehabilitasyon Dergisi JO - Turk J Physiother Rehabil PB - Türkiye Fizyoterapistler Derneği WT - DergiPark SN - 2651-4451 SP - 43 EP - 51 VL - 32 IS - 3 LA - en AB - Purpose: Spasticity is a common problem among people with Multiple Sclerosis (MS). This study aimed tocompare the effects of static stretching exercise (SSE) and functional stretching exercise (FSE) on lowerlimb spasticity, function, lower limb pain, active range of motion (ROM), and health-related quality of life(HRQOL) in patient with MS.Methods: Twenty-six participants were randomly allocated into two groups. SSE group (n=12) completeda four-week (12 sessions) SSE of hamstrings, quadriceps, hip adductors and plantar flexors muscles. FSEgroup 2 (n=12) completed a four-week (12 sessions) FSE of the same muscles. The outcome measureswere Modified Modified Ashworth Scale, Timed Up and Go Test, Timed 25 Foot Walk Test, active ROMassessment, Visual Analogue Scale, and EuroQoL 5-Dimension 5-Level questionnaire.Results: In each group, decrease of spasticity, improvement of functional tests, decrease of pain, increaseof ROM and increase of HRQOL were statistically significant compared to baseline (p0.05). A strongcorrelation was found between decreased spasticity and functional improvement in the SSE group (r=0.793, p=0.002). In the FSE group, there were moderate correlations between decreased spasticity and increased ROM (r=0.689, p=0.013) and between increased ROM and functional improvement (r=0.593, p=0.042). There was also a strong correlation between decreased spasticity and increased HRQOL (r=0.721, p=0.006).Conclusion: The regular four-weeks of SSE or FSE can decrease lower limb spasticity, improve function,decrease pain, increase active ROM and increase HRQOL in patients with MS. KW - Mobility Limitation KW - Multiple Sclerosis KW - Muscle Spasticity KW - Muscle Stretching Exercises KW - Quality of Life N2 - Amaç: Spastisite, Multipl Sklerozlu bireyler arasında yaygın bir sorundur. Bu çalışmanın amacı, MultiplSklerozlu bireylerde statik germe (SG) ve fonksiyonel germenin (FG) alt ekstremite spastisitesi, fonksiyon, altekstremite ağrısı, aktif eklem hareket açıklığı (EHA) ve sağlıkla ilişkili yaşam kalitesi (SİYK) üzerine etkilerinikarşılaştırmaktı.Yöntem: Yirmi altı katılımcı randomize edilerek iki gruba ayrıldı. SG grubuna (n=12) 4 hafta (12 seans)hamstring, quadriseps, kalça adduktor ve plantar fleksor kaslarının statik germe egzersizleri uygulandı. FGgrubuna (n=12) aynı kaslar için dört haftalık (12 seans) fonksiyonel germe egzersizleri uygulandı. Sonuçölçümü olarak Modifiye Modifiye Ashworth Skalası, Zamanlı Kalk ve Yürü Testi, Zamanlı 25 Adım YürümeTesti, aktif EHA değerlendirilmesi, Görsel Analog Skala ve Avrupa Yaşam Kalitesi Ölçeği-5 Boyut Anketikullanıldı.Sonuçlar: Her iki grupta da spastisitede azalma, fonksiyonel test sonuçlarında iyileşme, ağrıda azalma,EHA'nda e SİYK’nde meydana gelen artış başlangıç değerlerine kıyasla istatistiksel olarak anlamlıydı(p0,05). SGgrubunda spastisite azalma ve fonksiyonel iyileşme arasında güçlü bir korelasyon vardı (r=0,793, p=0.002).FG grubunda ise azalmış spastisite ile artmış EHA arasında (r=0,689, p=0.013) ve artmış EHA ile fonksiyoneliyileşme arasında (r=0,593, p=0.042) orta düzeyde korelasyon vardı. Azalan spastisite ile SİYK artışı arasındaise güçlü bir korelasyon vardı (r=0,721, p=0.006)Tartışma: Düzenli olarak dört hafta boyunca uygulanan SG veya FG, multipl sklerozlu hastalarda altekstremite spastisitesini azaltabilir, fonksiyonu iyileştirebilir, ağrıyı azaltabilir, aktif EHA’nı ve SİYK’niartırabilir. CR - 1. Rizzo M, Hadjimichael O, Preiningerova J, Vollmer T. Prevalence and treatment of spasticity reported by multiple sclerosis patients. Multiple Sclerosis Journal. 2004;10(5):589-95. CR - 2. Barnes M, Kent R, Semlyen J, McMullen K. Spasticity in multiple sclerosis. Neurorehabilitation and neural repair. 2003;17(1):66-70. CR - 3. Lance JW. The control of muscle tone, reflexes, and movement: Robert Wartenberg Lecture. Neurology. 1980 Dec;30(12):1303-13. PubMed PMID: 7192811. Epub 1980/12/01. eng. CR - 4. Dietz V, Sinkjaer T. Spastic movement disorder: impaired reflex function and altered muscle mechanics. The Lancet Neurology. 2007;6(8):725-33. CR - 5. Flachenecker P, Henze T, Zettl U. Spasticity in patients with multiple sclerosis–clinical characteristics, treatment and quality of life. Acta Neurologica Scandinavica. 2014;129(3):154-62. CR - 6. Bethoux F. Gait disorders in multiple sclerosis. CONTINUUM: Lifelong Learning in Neurology. 2013;19(4):1007-22. CR - 7. Bovend'Eerdt TJ, Newman M, Barker K, Dawes H, Minelli C, Wade DT. The effects of stretching in spasticity: a systematic review. Archives of physical medicine and rehabilitation. 2008;89(7):1395-406. CR - 8. White LJ, Dressendorfer RH. Exercise and multiple sclerosis. Sports medicine. 2004;34(15):1077-100. CR - 9. Halabchi F, Alizadeh Z, Sahraian MA, Abolhasani M. Exercise prescription for patients with multiple sclerosis; potential benefits and practical recommendations. BMC neurology. 2017;17(1):185. CR - 10. Lederman E. Therapeutic Stretching in Physical Therapy E-Book: Towards a Functional Approach: Elsevier Health Sciences; 2013. CR - 11. Fragoso YD, Santana DLB, Pinto RC. The positive effects of a physical activity program for multiple sclerosis patients with fatigue. NeuroRehabilitation. 2008;23(2):153-7. CR - 12. Shams A, Taheri H. The effect of 8 weeks selective training programs with instructions focus of attention on walking speed of patients with multiple sclerosis. medical journal of mashhad university of medical sciences. 2015;57(9):969-75. CR - 13. Sosnoff JJ, Finlayson M, McAuley E, Morrison S, Motl RW. Home-based exercise program and fall-risk reduction in older adults with multiple sclerosis: phase 1 randomized controlled trial. Clinical rehabilitation. 2014;28(3):254-63. CR - 14. ERTEKiN Ö, Özakbas S, Idiman E, Algun ZC. Quality of life, fatigue and balance improvements after home-based exercise program in multiple sclerosis patients/Multipl skleroz hastalarinda ev egzersiz programinin sonrasinda yasam kalitesi, yorgunluk ve dengedeki iyilesmeler. Noro-Psikyatri Arsivi. 2012;49(1):33. CR - 15. Alaee S, Fathi M, Moazami M. Effect of a six-week concurrent exercise (stretching and aerobic) and the consumption of tetra hydro cannabinol additive on fatigue severity level among female MS patients. Advances in Environmental Biology. 2014:924-30. CR - 16. Freeman J, Allison R. Group exercise classes in people with multiple sclerosis: a pilot study. Physiotherapy Research International. 2004;9(2):104-7. CR - 17. Tarakci E, Yeldan I, Huseyinsinoglu BE, Zenginler Y, Eraksoy M. Group exercise training for balance, functional status, spasticity, fatigue and quality of life in multiple sclerosis: a randomized controlled trial. Clinical rehabilitation. 2013;27(9):813-22. CR - 18. Ayaregar M, Hosseini M, Shakeri N, Ashktorab T, Zohari Anbouhi S. The effect of stretching exercises on the severity of restless legs syndrome symptoms in patients with multiple sclerosis. Journal of hayat. 2017;23(1):7-16. CR - 19. Hugos CL, Bourdette D, Chen Y, Chen Z, Cameron M. A group-delivered self-management program reduces spasticity in people with multiple sclerosis: A randomized, controlled pilot trial. Multiple Sclerosis Journal–Experimental, Translational and Clinical. 2017;3(1):2055217317699993. CR - 20. Ponzano M, Beratto L, Mazza C, Di Tommaso S, Abate Daga F, Allois R, et al. Benefits of Static Stretching, Pliates® and Elastic Bands Resistance Training on Patients with Relapsing-Remitting Multiple Sclerosis: A Longitudinal Study. Ponzano et al. J Neurol Neurophysiol. 2017;8(438):2. CR - 21. Schulz KF, Grimes DA. Generation of allocation sequences in randomised trials: chance, not choice. The Lancet. 2002;359(9305):515-9. CR - 22. McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society. 2001;50(1):121-7. CR - 23. Gibson BE. Stretching with a Helper for People with MS: An Illustrated Manual: National Multiple Sclerosis Society; 2001. CR - 24. Elshafey MA, Abd-Elaziem A, Gouda RE. Functional stretching exercise submitted for spastic diplegic children: a randomized control study. Rehabilitation research and practice. 2014;2014. CR - 25. Ansari NN, Naghdi S, Younesian P, Shayeghan M. Inter-and intrarater reliability of the Modified Modified Ashworth Scale in patients with knee extensor poststroke spasticity. Physiotherapy theory and practice. 2008;24(3):205-13. CR - 26. Sebastião E, Sandroff BM, Learmonth YC, Motl RW. Validity of the timed up and go test as a measure of functional mobility in persons with multiple sclerosis. Archives of physical medicine and rehabilitation. 2016;97(7):1072-7. CR - 27. Phan-Ba R, Pace A, Calay P, Grodent P, Douchamps F, Hyde R, et al. Comparison of the timed 25-foot and the 100-meter walk as performance measures in multiple sclerosis. Neurorehabilitation and neural repair. 2011;25(7):672-9. CR - 28. Svendsen KB, Jensen TS, Overvad K, Hansen HJ, Koch-Henriksen N, Bach FW. Pain in patients with multiple sclerosis: a population-based study. Archives of Neurology. 2003;60(8):1089-94. CR - 29. Donatelli RA, Wooden MJ. Orthopaedic Physical Therapy-E-Book: Elsevier health sciences; 2009. CR - 30. Herdman M, Gudex C, Lloyd A, Janssen M, Kind P, Parkin D, et al. Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5L). Quality of Life Research. 2011 December 01;20(10):1727-36. CR - 31. Cohen J. Statistical power analysis for the behavioral sciences: Routledge; 2013. CR - 32. Odeen I. Reduction of muscular hypertonus by long-term muscle stretch. Scandinavian journal of rehabilitation medicine. 1981;13(2-3):93-9. CR - 33. Ghasemi E, Khademi-Kalantari K, Khalkhali-Zavieh M, Rezasoltani A, Ghasemi M, Baghban AA, et al. The Effect of Functional Stretching Exercises on Neural and Mechanical Properties of the Spastic Medial Gastrocnemius Muscle in Patients with Chronic Stroke: A Randomized Controlled Trial. Journal of Stroke and Cerebrovascular Diseases. 2018;27(7):1733-42. CR - 34. Rampello A, Franceschini M, Piepoli M, Antenucci R, Lenti G, Olivieri D, et al. Effect of aerobic training on walking capacity and maximal exercise tolerance in patients with multiple sclerosis: a randomized crossover controlled study. Physical therapy. 2007;87(5):545-55. CR - 35. Hoang PD, Gandevia SC, Herbert RD. Prevalence of joint contractures and muscle weakness in people with multiple sclerosis. Disability and rehabilitation. 2014;36(19):1588-93. UR - https://doi.org/10.21653/tjpr.762021 L1 - https://dergipark.org.tr/tr/download/article-file/1181836 ER -