@article{article_775303, title={The Evaluation of Colposcopic Examinations and Cervical Histopathology Results of Women With Abnormal PAP-smear and/or HPV Positivity: A Sample From Amasya}, journal={Medical Journal of Western Black Sea}, volume={4}, pages={142–149}, year={2020}, author={Şahin, Banuhan and Güner, Esra and Kara, Osman Fadıl}, keywords={HPV, kolposkopi, pap-smear, punch biyopsi, serviks kanseri}, abstract={Aim: To analyse the cervical biopsies and colopscopic examinations made of women who presented at our clinic with abnormal pap-smear and/or human papilloma virus (HPV) positivity. Material and Method: A retrospective examination was made of the colopscopy findings, number of punch biopsies and final histo-pathological results of patients who presented at the gynaecology polyclinic between January 2018 and January 2020 with a smear result showing atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesions (LGSIL), high-grade squamous intraepithelial lesions (HGSIL), and atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H), and/or HPV test was 16, 18 and other types of positivity. The Chi-square test was applied in the comparisons of the findings. Results: Evaluation was made of 214 patients with a mean age of 46.54±10.76 years. The pap-smear results were recorded as ASCUS in 71 (33.2%) patients, ASC-H in 2 (0.9%), LGSIL in 23 (10.7%), HGSIL in 8 (3.7%) and normal or showing inflammation in 110 (51.4%). HPV 16 positivity was determined in 58 (27.1%) patients, HPV 18 positivity in 12 (5.6%), other high-risk type HPV positivity in 84 (39.3%) and other type HPV positivity in 53 (24.8%). The colposcopy findings were recorded as leukoplakia in 60 (28%) patients, a punctuation appearance in 40 (18.7%), mosaic appearance in 26 (12.1%), and atypical vascularisation in 24(11.2%). A single punch biopsy was taken from 53 (24.8%) patients, and multiple biopsies were taken from 161 (75.2%). The histo-pathological results were reported as LGSIL in 45 (21%) patients, HGSIL in 15 (7%) and carcinoma in 1 (0.5%). No correlation was determined between the colopscopic examination findings and the number of punch biopsies (p=0.655). As the number of punch biopsies increased, so the probability of LGSIL, HGSIL, and carcinoma increased (p=0.006). Conclusion: While the colposcopy examination findings did not affect the number of punch biopsies, it was seen that as the number of punch biopsies increased so did the probability of capturing cervical premalignant and malignant lesions. When no lesion is seen in the colposcopy examination, the number of cervical punch biopsies should be increased.}, number={3}, publisher={Zonguldak Bülent Ecevit Üniversitesi}, organization={Amasya Üniversitesi Etik Kurulu}