TY - JOUR T1 - Evaluation of patients with multiple sclerosis and sleep disorders AU - İnanç, Yılmaz AU - Bavli, Songül AU - Tuncel, Deniz PY - 2021 DA - July DO - 10.28982/josam.793016 JF - Journal of Surgery and Medicine JO - J Surg Med PB - Selçuk BAŞAK WT - DergiPark SN - 2602-2079 SP - 665 EP - 669 VL - 5 IS - 7 LA - en AB - Background/Aim: Sleep disorders are often reported by MS patients and various studies have shown sleep disorders to be more widespread in MS patients than in healthy control groups. However, despite the high frequency, they are often overlooked. This study aimed to determine the characteristics of fatigue and daytime sleepiness in MS patients, the underlying factors, and their relationship for testing the reliability of subjective scales and establishing when patients presenting with these symptoms should be referred to a sleep specialist. Methods: The patients enrolled in this cohort study were aged >18 years, had a confirmed diagnosis of relapsing remitting MS, were in the remission phase, had not taken steroids within the last 3 months, and had complaints of fatigue, daytime sleepiness, and sleep disorders. Patients with EDSS score KW - Multiple sclerosis KW - Sleep disorders KW - Polysomnography CR - 1. Dobson R, Giovannoni G. Multiple sclerosis–a review. European Journal of Neurology. 2019;26(1):27-40. doi: 10.1111/ene.13819 CR - 2. Braley T J, Chervin R D. Fatigue in Multiple Sclerosis: Mechanisms, Evaluation, and Treatment. Sleep. 2010 Aug 1; 33(8): 1061–1067. doi: 10.1093/sleep/33.8.1061 CR - 3. Freal J, Kraft G, Coryell J. Symptomatic fatigue in multiple sclerosis. Archives of Physical Medicine and Rehabilitation. 1984;65(3):135-8. PMID: 6703889 CR - 4. Fisk JD, Pontefract A, Ritvo PG, Archibald CJ, Murray T. The impact of fatigue on patients with multiple sclerosis. Canadian Journal of Neurological Sciences. 1994;21(1):9-14. PMID: 8180914 CR - 5. Krupp LB, Alvarez LA, LaRocca NG, Scheinberg LC. Fatigue in multiple sclerosis. Archives of Neurology. 1988;45(4):435-7. doi: 10.1001/archneur.1988.00520280085020 CR - 6. Veauthier C, Paul F. Fatigue in multiple sclerosis: which patient should be referred to asleep specialist? Multiple Sclerosis Journal. 2012;18(2):248. doi: 10.1177/1352458511411229 CR - 7. Popp RF, Fierlbeck AK, Knüttel H, König N, Rupprecht R, Weissert R et al. Daytime sleepiness versus fatigue in patients with multiple sclerosis: a systematic review on the Epworth sleepiness scale as an assessment tool. Sleep Medicine Reviews. 2017;32:95-108. doi: 10.1016/j.smrv.2016.03.004 CR - 8. Merkelbach S, Schulz H, Kölmel H, Gora G, Klingelhöfer J, Dachsel R et al. Fatigue, sleepiness, and physical activity in patients with multiple sclerosis. Journal of Neurology. 2011;258(1):74-9. doi: 10.1007/s00415-010-5684-3 CR - 9. Mendozzi L, Tronci F, Garegnani M, Pugnetti L. Sleep disturbance and fatigue in mild relapsing remitting multiple sclerosis patients on chronic immunomodulant therapy: an actigraphic study. Multiple Sclerosis Journal. 2010;16(2):238-47. doi: 10.1177/1352458509354551 CR - 10. Shahrbanian S, Duquette P, Mayo N. Impairment, disability and fatigue in multiple sclerosis. Caspian Journal of Internal Medicine. 2018;9(3):244-51. doi: 10.22088/cjim.9.3.244 CR - 11. Manconi M, Fabbrini M, Bonanni E, Filippi M, Rocca M, Murri L et al. High prevalence of restless legs syndrome in multiple sclerosis. European journal of Neurology. 2007;14(5):534-9. doi: 10.1111/j.1468-1331.2007.01740.x CR - 12. Manconi M, Ferini-Strambi L, Filippi M, Bonanni E, Iudice A et al. Italian R. Study Group Multicenter case-control study on restless legs syndrome in multiple sclerosis: the REMS study. Sleep. 2008;31(7):944-52. PMCID: PMC2491510 PMID: 18655317 CR - 13. Ferini-Strambi L, Filippi M, Martinelli V, Oldani A, Rovaris M, Zucconi M et al. Nocturnal sleep study in multiple sclerosis: correlations with clinical and brain magnetic resonance imaging findings. Journal of the Neurological Sciences. 1994;125(2):194-7. doi: 10.1016/0022-510x(94)90035-3 CR - 14. Marrie RA, Reider N, Cohen J, Trojano M, Sorensen PS, Cutter G et al. A systematic review of the incidence and prevalence of sleep disorders and seizure disorders in multiple sclerosis. Multiple Sclerosis Journal. 2015;21(3):342-9. doi: 10.1177/1352458514564486 CR - 15. Lin M, Krishnan AV, Eckert DJ. Central sleep apnea in multiple sclerosis: a pilot study. Sleep Breath. 2017;21(3):691-6. doi: 10.1007/s11325-016-1442-9 CR - 16. Ohayon MM, Priest RG, Zulley J, Smirne S, Paiva T. Prevalence of narcolepsy symptomatology and diagnosis in the European general population. Neurology. 2002;58(12):1826-33. doi: 10.1212/wnl.58.12.1826. UR - https://doi.org/10.28982/josam.793016 L1 - https://dergipark.org.tr/tr/download/article-file/1283252 ER -