TY  - JOUR
T1  - Effect of Rosuvastatin on Fasting and Postprandial Lipid Profile in Hypertriglyceridemia Patients
AU  - Çakmak, Abdulkadir
PY  - 2021
DA  - November
Y2  - 2021
DO  - 10.22399/ijcesen.827419
JF  - International Journal of Computational and Experimental Science and Engineering
JO  - IJCESEN
PB  - İskender AKKURT
WT  - DergiPark
SN  - 2149-9144
SP  - 146
EP  - 155
VL  - 7
IS  - 3
LA  - en
AB  - Abstract: Background: Coronary heart disease (CHD) is a main cause of mortality due to cardiovascular diseases. Hypertriglyceridemia (HTG) is a multifactorial condition implicated in the pathogenesis of CHD. Serum triglyceride (TG) levels were routinely obtained under fasting conditions; however, recent evidences implicate that postprandial triglyceride levels may be more important for CHD risk. Aim: Aim of this study was to investigate the effect of rosuvastatin on fasting and postprandial TG levels in the patients with borderline-high TG levels.Methods: 51 patients (18-75 years old; 26 female) with LDL-c between 100 and 160 mg/dL and triglyceride levels between 150 and 300 mg/dL were included in this study. Basal fasting and postprandial lipid profile and hsCRP levels of the patients were obtained and patients were requested to take 10 mg/day rosuvastatin for one month. At the end of one month, the measurements were repeated.Results: Rosuvastatin significantly decreased both fasting and postprandial TG levels compared to basal levels (p
KW  - Coronary heart disease
KW  - Hypertriglyceridemia
KW  - Rosuvastatin
KW  - Triglycerides
CR  - Referans1 
Han SH, Nicholls SJ, Sakuma I, Zhao D, Koh KK. Hypertriglyceridemia and Cardiovascular Diseases: Revisited. Korean circulation journal. 2016;46(2):135-44. doi:10.4070/kcj.2016.46.2.135.
CR  - Referans2
Egeland GM, Igland J, Sulo G, Nygard O, Ebbing M, Tell GS. Postprandial triglycerides predict incident acute myocardial infarction among those with favourable HDL-cholesterol: Cohort Norway. Eur J Prev Cardiol. 2015;22(7):872-81. doi:10.1177/2047487314535681
Referans3
Masuda D, Yamashita S. Postprandial Hyperlipidemia and Remnant Lipoproteins. Journal of atherosclerosis and thrombosis. 2017;24(2):95-109. doi:10.5551/jat.RV16003
UR  - https://doi.org/10.22399/ijcesen.827419
L1  - https://dergipark.org.tr/tr/download/article-file/1402411
ER  -