TY  - JOUR
T1  - Evaluation of Adjuvant Radiotherapy Efficacy in Pure Ductal Carcinoma In situ Patients According to Different Variables
TT  - Saf Duktal Karsinoma İn situ’lu Hastalarda Adjuvan  Radyoterapi Etkinliğinin Farklı Değişkenlere Göre  Değerlendirilmesi
AU  - Karaca, Feryal
AU  - Menteş, Selahattin
AU  - Çil, Timuçin
AU  - Keskin, Sıddık
PY  - 2021
DA  - November
Y2  - 2021
DO  - 10.17517/ksutfd.828771
JF  - Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi
JO  - KSU Medical Journal
PB  - Kahramanmaraş Sütçü İmam Üniversitesi
WT  - DergiPark
SN  - 1303-6610
SP  - 369
EP  - 374
VL  - 16
IS  - 3
LA  - en
AB  - Introduction: Ductal carcinoma in situ  is a non-invasive pathology  of   breast cancer. Pure  ductal carcinoma in situ  is extremely rare, although it is often accompanied by invasive breast cancers.  Materials and Methods:The study included 27 patients who applied to the Adana City Training and Research Hospital Radiation Oncology outpatient clinic and received adjuvant   radiotherapy with a diagnosis of pure  ductal carcinoma in situ. Results:The mean age of the patients was 45.33 in the premenopausal period and 59.83 in the postmenopausal period, and a statistically significant result was obtained when the age of both groups was compared (p = 0.001). Age and tumor diameter (38.8%) was assessed statistically significant (p <0.05). it can be stated that the tumor diameter tends to increase with increasing age. Conclusion: Age, tumor size, receptor status, operation margin, histopathological grade, multifocality and adjuvant treatments are effective on local recurrens and survival in ductal carcinoma in situ  patients. Patients diagnosed with ductal carcinoma in situ receive adjuvant radiotheray after breast conserving surgery, reducing the risk of  local recurrens.
KW  - ductal carcinoma in situ
KW  - adjuvant radiotherapy
KW  - local recurrence
KW  - breast cancer
N2  - Introduction: Ductal carcinoma in situ  is a non-invasive pathology  of   breast cancer. Pure  ductal carcinoma in situ  is extremely rare, although it is often accompanied by invasive breast cancers.  Materials and Methods:The study included 27 patients who applied to the Adana City Training and Research Hospital Radiation Oncology outpatient clinic and received adjuvant   radiotherapy with a diagnosis of pure  ductal carcinoma in situ. Results:The mean age of the patients was 45.33 in the premenopausal period and 59.83 in the postmenopausal period, and a statistically significant result was obtained when the age of both groups was compared (p = 0.001). Age and tumor diameter (38.8%) was assessed statistically significant (p <0.05). it can be stated that the tumor diameter tends to increase with increasing age. Conclusion: Age, tumor size, receptor status, operation margin, histopathological grade, multifocality and adjuvant treatments are effective on local recurrens and survival in ductal carcinoma in situ  patients. Patients diagnosed with ductal carcinoma in situ receive adjuvant radiotheray after breast conserving surgery, reducing the risk of  local recurrens.
CR  - 1.	Groen EJ, Elshof LH, Visser LL. Finding the balance between over- and under-treatment of ductalcarcinoma in situ (DCIS). The Breast 2017;31:274-28.
CR  - 2.	Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, Van de Vijver MJ. WHO Classification of Tumours of the Breast, Fourth Edition. Lyon: IARC Press; 2012. 2.
UR  - https://doi.org/10.17517/ksutfd.828771
L1  - https://dergipark.org.tr/tr/download/article-file/1406846
ER  -