TY  - JOUR
T1  - CD45 pozitif ve CD45 negatif neoplastik plazma hücreleri saptanan multiple miyelom olgusu
TT  - A case of multiple myeloma with CD45 positive and CD45 negative neoplastic plasma cells
AU  - Gezer, Oya
AU  - Gülüm, Cemil
AU  - Bobuşoğlu, Onur
AU  - Tombak, Anıl
AU  - Çimen, Mehmet Burak
AU  - Tamer, Lülüfer
PY  - 2021
DA  - August
Y2  - 2021
DO  - 10.26559/mersinsbd.864232
JF  - Mersin Üniversitesi Sağlık Bilimleri Dergisi
JO  - Mersin Univ Saglık Bilim Derg
PB  - Mersin Üniversitesi
WT  - DergiPark
SN  - 1308-0830
SP  - 360
EP  - 365
VL  - 14
IS  - 2
LA  - tr
AB  - Multiple Miyelom (MM) kemik iliğindeki plazma hücrelerinin üretimini etkileyen bir kanser türüdür. B hücrelerinin farklılaşması sonucu oluşan, immunglobulin (antikor) üreten plazma hücreleri miyelom hücresine dönüşünce, antikor yerine monoklonal protein (M-protein) üretirler. Miyeloma hücreleri genellikle CD45 ekspresyonu göstermezler. Bu makalede akım sitometrik immünfenotipleme çalışmasında CD45(+) ve CD45(-) hücreleri birlikte taşıyan bir multiple miyelom vakası sunulmaktadır.
KW  - CD45(+)
KW  - CD45(-)
KW  - Multiple Miyelom
KW  - akım sitometri
N2  - Multiple Myeloma (MM) is a type of cancer that affects the plasma cells proliferation in the bone marrow. When plasma cells that produce immunoglobulin (antibody), which are formed as a result of differentiation of B cells, turn into myeloma cells, they produce monoclonal protein (M-protein) instead of antibody. Myeloma cells are usually detected as CD45(-). In this article, we present a case of multiple myeloma carrying CD45(+) and CD45(-) cells together in a flow cytometric immunophenotyping study.
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CR  - 2.	Schentrup D. Diagnosing multiple myeloma in primary care. Clinician Reviews. 2018;16-21.
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UR  - https://doi.org/10.26559/mersinsbd.864232
L1  - http://dergipark.org.tr/tr/download/article-file/1519718
ER  -