TY - JOUR T1 - The impact and relationship of inflammatory markers and radiologic involvement in the COVID-19 patients AU - Sayar, Merve Sefa AU - Bulut, Dilek AU - Çelik, Sebahattin AU - Burulday, Veysel AU - Sarıkaya, Remzi AU - Kurt, Nurettin PY - 2021 DA - July DO - 10.32322/jhsm.904196 JF - Journal of Health Sciences and Medicine JO - J Health Sci Med /JHSM /jhsm PB - MediHealth Academy Yayıncılık WT - DergiPark SN - 2636-8579 SP - 416 EP - 421 VL - 4 IS - 4 LA - en AB - Aim: In the study, it was aimed to investigate the relationship between inflammatory markers and radiology in COVID-19 patients. Material and Method: The study was conducted in the quarantine wards of a tertiary hospital between March and June 2020. Patients with a definite diagnosis of COVID-19 were included in the study. The lung damage of the patients caused by COVID-19 was determined by computed tomography and the relationship between lung damage and inflammatory markers was examined.Results: The mean age of 259 COVID-19 patients included in the study was 61.96 ± 14.076. Except for thrombocytopenia, all variables such as ferritin, D-dimer, thoracic computerized tomography (CT) involvement rates were significantly poorer in the patients requiring the care in ICU than the patients in wards (p KW - COVID-19 KW - intensive care unit KW - prognosis KW - SARS-CoV-2 CR - Khabbaz R, Beth BP, Schuchat A, et al. Emerging and reemerging infectious disease threats. In: Mandel, Dougles, and Bennett’s Principles and Practice of Infectious Disease, Bennett JE, Dolin R, Blaser MJ (eds). 8rd ed. Philadelphia: Elsevier; 2015: 158-77. CR - World Health Organization: COVID-19 Weekly Epidemiological Update-24 November 2020. Available at: <https://www.who.int/publications/m/item/weekly-epidemiological-update---24-november-2020> Accessed November 25, 2020. CR - Cao W, Li T. COVID-19: towards understanding of pathogenesis. Cell Res 2020; 5: 367–9. CR - Shi Y, Yu X, Zhao H, et al. Host susceptibility to severe COVID-19 and establishment of a host risk score: Findings of 487 cases outside Wuhan. Crit Care 2020; 1: 2–5. CR - Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China. Jama 2020; 13: 1239-42. CR - Zhai P, Ding Y, Wu X, et al. The epidemiology, diagnosis and treatment of COVID-19. Int J Antimicrob Agents 2020; 5: 105955. CR - TR Ministry of Health, General Directorate of Public Health. COVID-19 (SARS-CoV-2 Infection) Treatment of Adult Patients 19 June 2020. Available at: <https://covid19bilgi.saglik.gov.tr/depo/rehberler/covid-19-rehberi/COVID-19_REHBERI_ERISKIN_HASTA_TEDAVISI.pdf>. Accessed July 1, 2020. CR - Pan F, Ye T, Sun P. Time course of lung changes at chest ct during recovery from coronavirus disease 2019 (COVID-19). Radiology 2020; 295: 715–21. CR - Li K, Wu J, Wu F, et al. The clinical and chest ct features associated with severe and critical COVID-19 pneumonia. Invest Radiol 2020; 6: 327-31. CR - China-WHO Expert team . Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). Available at <https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf >. Accessed by July 1,2020. CR - World Health Organization: Clinical Care Severe Acute Respiratory Infection: Tool kit. Available at: < https://apps.who.int/iris/bitstream/handle/10665/331736/WHO-2019-nCoV-SARI_toolkit-2020.1-eng.pdf?sequence=1&isAllowed=y>. Accessed by July 1, 2020. CR - Harapan H, Itoh N, Yufika A, et al. Coronavirus disease 2019 (COVID-19) : A literature review. J Infect Public Health 2020; 5: 667–73. CR - Sohrabi C, Alsafi Z, O’Neill N, et al. World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19). Int J Surg 2020; 76: 71–6. CR - Shi Y, Wang G, Cai XP, et al. An overview of COVID-19. J Zhejiang Univ Sci B 2020; 5: 343–60. CR - Yang J, Zheng Y, Gou X, et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis 2020; 94: 91–5. CR - Tufan A, Avanoğlu Güler A, Matucci-Cerinic M. COVID-19, immune system response, hyperinflammation and repurposing antirheumatic drugs. Turk J Med Sci 2020; 50: 620–32. CR - Shi H, Han X, Jiang N, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis 2020; 4: 425-34. CR - Li R, Tian J, Yang F, et al. Clinical characteristics of 225 patients with COVID-19 in a tertiary hospital near Wuhan, China. J Clin Virol 2020; 127: 104363. CR - Guan W, Ni Z, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020; 18: 1708–20. CR - Zhang L, Yan X, Fan Q, et al. D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. J Thromb Haemost 2020; 6: 1324–9. CR - Kamps BS, Hoffmann C (editors). Diagnostic Tests and Prosedures. In: COVID reference. Fourth ed., Hamburg: Steinhauser-Verlag; 2020: 155-85. CR - World Health Organization: Use of chest imaging in COVID-19. Available at: https://www.who.int/publications/i/item/use-of-chest-imaging-in-covid-19. Accessed by July 1, 2020. CR - Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A. Coronavirus Disease 2019 (COVID-19): A systematic review of ımaging findings in 919 patients. AJR Am J Roentgenol 2020; 1: 87–93. CR - Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges. Int J Antimicrob Agents 2020; 3: 105924. CR - Song F, Shi N, Shan F, et al. Emerging 2019 novel coronavirus (2019-NCoV) pneumonia. Radiology 2020; 1: 210–7. UR - https://doi.org/10.32322/jhsm.904196 L1 - https://dergipark.org.tr/tr/download/article-file/1665796 ER -