@article{article_927519, title={The importance of Neutrophil-Lymphocyte Ratio, Monocyte-Lymphocyte Ratio, and Thrombocyte-Lymphocyte ratio in addition to abnormal laboratory parameters in COVID-19 pneumonia}, journal={Ege Tıp Dergisi}, volume={60}, pages={394–401}, year={2021}, author={Keni Begendi, Nermin and Kacar, Fatma and Dağ, Mikail and Tarakçı, Arzu and Özdemir Armağan, Şule and Saçkan, Fatih and Kızılarslanoğlu, Muhammet Cemal}, keywords={COVID-19 pnömonisi, monosit, lenfosit, eozinofil, NLO, MLO, TLO}, abstract={Objective: We aimed to examine the importance of the neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR) and thrombocyte-lymphocyte ratio (TLR) in addition to laboratory parameters in terms of pneumonia between patients with and without pneumonia diagnosed with COVID-19 infection.
Material and Methods: In our retrospective study, 506 patients diagnosed with COVID-19 who were hospitalized and treated between April 2020 and July 2020 were included. While 50.6% (n:256) of the patients had pneumonia, 49.4% (n:250) did not have. File informations were scanned; the demographic data, hospitalization and discharge laboratory parameters were recorded.
Results: The median age of the patients was 44.5 (16-89) years, 55.5% (n = 281) of them were male. The median age of patients with pneumonia was higher than those without pneumonia, and the frequency of female gender was higher (p <0.05 for both conditions). The lymphocyte count at hospitalization and discharge was significantly lower in patients with pneumonia (p <0.001, 0.007, respectively). The count of eosinophils at hospitalization was significantly lower in patients with pneumonia (p <0.001). NLR and TLR values were significantly higher in patients with pneumonia at admission and discharge (p <0.008, <0.007, respectively for NLR and p <0.001, p<0.001 respectively for TLR). MLR values at discharge were higher in patients with pneumonia (p = 0.001). In ROC analyzes made in terms of predicting pneumonia; hospitalization CRP level, eosinophil, monocyte counts and TLR values were found to be important variables.
Conclusion: In this study, the importance of monocyte, eosinophil counts and TLR values in COVID-19 pneumonia was demonstrated.}, number={4}, publisher={Ege Üniversitesi}, organization={Sağlık Bilimleri Üniversitesi, Konya Şehir Hastanesi}