TY - JOUR T1 - Böbrek Nakli: Covid-19 Etkisi TT - Kidney Transplantation: Effect of Covid-19 AU - Özşaker, Esma PY - 2021 DA - December DO - 10.52976/vansaglik.944910 JF - Van Sağlık Bilimleri Dergisi JO - Van Sağ Bil Derg PB - Van Yüzüncü Yıl Üniversitesi WT - DergiPark SN - 2667-5072 SP - 352 EP - 360 VL - 14 IS - 3 LA - tr AB - Ciddi akut solunum yetmezliğine ve ölüme neden olabilen Covid-19 hastalığı, tüm dünyada ciddi sağlık problemine yol açmıştır. Koronavirüs hastalığının hızla yayılmasına bağlı küresel sağlık krizi, sağlık hizmetlerinin her alanında büyük aksamalara neden olmuştur. Organ nakilleri de Covid-19’dan en çok etkilenen birimler arasındadır. Böbrek nakli, son dönem böbrek yetmezliği olan bireylerde yaşam süresini ve kalitesini artırmak amacıyla canlı ya da kadavra donörden alınan bir böbreğin nakledilmesi işlemidir. Böbrek nakli alıcıları, bağışıklık sisteminin baskılanmış olma durumu ve diyabet, hipertansiyon veya kalp hastalığı gibi komorbiditeler nedeniyle Covid-19 enfeksiyonuna yakalanma ve hastalığın şiddeti bakımından daha büyük bir risk altındadır. Bu makalede, Covid-19’un organ bağışı ve nakli, böbrekler, böbrek nakli bekleme listesinde olan hastalar ve böbrek nakli alıcıları üzerindeki etkilerine yer verilmiştir. KW - Covid-19 virüsü KW - Böbrek nakli KW - Organ bağışı N2 - Covid-19 disease, which can cause severe acute respiratory failure and death, has caused serious health problems all over the world. The global health crisis due to the rapid spread of coronavirus disease has caused major disruptions in all areas of healthcare. Organ transplants are among the units most affected by Covid-19. Kidney transplantation is the transplantation of a kidney taken from a living or cadaver donor in order to increase the life span and quality of individuals with end-stage renal failure. Kidney transplant recipients are at a greater risk of contracting Covid-19 infection and disease severity due to their immunosuppressed state and comorbidities such as diabetes, hypertension, or heart disease. In this article, the effects of Covid-19 on organ donation and transplantation, kidneys, kidney transplant waiting list patients, and kidney transplant recipients are given. CR - Alasfar S, Avery RK. The impact of COVID-19 on kidney transplantation. Nat Rev Nephrol.2020; 16: 568–569. https://doi.org/10.1038/s41581-020-00340-z CR - American Society of Transplantation. AST COVID-19 Information, https://www.myast.org/covid-19-information CR - Azzi Y, Parides M, Alani O, Loarte-Campos P, Bartash R, Forest S, et al. COVID-19 infection in kidney transplant recipients at the epicenter of pandemics. Kidney International.2020; 98: 1559–1567. CR - Bayrakcı N, Özkan G. Management of Nephrology Clinics in COVID-19 Pandemic. Namık Kemal Medical Journal. 2020; 8(3): 570 –578. CR - Bilge Y, Bilge Y. Investigation of the effects of coronavirus and social isolation on psychological symptoms in terms of psychological resilience and coping styles. Klinik Psikiyatri Dergisi.2020; 23: 38-51 CR - Boyarsky BJ, Po-Yu Chiang T, Werbel WA, Durand CM, Avery RK, Getsin SN, et al. Early impact of COVID-19 on transplant center practices and policies in the United States. Am J Transplant. 2020; 20(7): 1809-1818. https://doi.org/10.1111/ajt.15915 CR - Centers for Disease Control and Prevention-CDC. (2020). Coronavirus Disease 2019 (COVID-19): Who is at risk for severe disease from COVID-19?, 2020. https://www.cdc.gov/coronavirus/2019-ncov/hcp/faq.html(Erişim Tarihi: 22.02.2020). CR - Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, Li J, Yao Y, Ge S, Xu G. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020; 97(5):829-838. https://doi.org/10.1016/j.kint.2020.03.005 CR - Demirağ H, Hintistan S. Clinical Management and Nursing of COVID-19. Gümüşhane University Journal of Health Sciences.2020; 9(2): 222 – 231. CR - Devresse A, Belkhir L, Vo B, Ghaye B, Scohy A, Kabamba B, et al. COVID-19 Infection in Kidney Transplant Recipients: A Single-Center Case Series of 22 Cases From Belgium. Kidney Med. 2020 Jun 15;2(4):459-466. https://doi.org/10.1016/j.xkme.2020.06.001 EAU Renal Transplantation Guidelines, Recommendations from the EAU Renal Transplantation Guidelines Panel applicable during the COVID-19 pandemic. https://uroweb.org/wp-content/uploads/Covid-19-EAU-Renal-Transplantation-recommendations.pdf CR - Fidan HK, Gülleroğlu KS, Atak Yücel A. Transplantasyon hastalarında COVID-19 ve immün cevap. Atak Yücel A, editör. İmmünoloji ve COVID-19. 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.112-6. CR - Gonzalez J, Ciancio G. Early experience with COVID-19 in kidney transplantation recipients: update and review. Int Braz J Urol. 2020 Jul;46(suppl.1):145-155. https://doi.org/10.1590/S1677-5538.IBJU.2020.S114 CR - Johnson KM, Belfer JJ, peterson gR, Boelkins MR, et al. Managing COVID-19 in Renal Transplant Recipients: A Review of Recent Literature and Case supporting Corticosteroid sparing Immunosuppresion pharmacotherapy. 2020; 27. https://doi.org/10.1002/phar.2410 CR - Karataş Z. COVID-19 Pandemisinin Toplumsal Etkileri, Değişim ve Güçlenme. Türkiye Sosyal Hizmet Araştırmaları Dergisi. 2020; 4(1): 3-15. CR - Kataria A, Yakubu I, Winstead R, Gowda M, Gupta G. COVID-19 in Kidney Transplantation: Epidemiology, Management Considerations, and the Impact on Kidney Transplant Practice. Transplantation Direct. 2020; 6(8): e582. https://doi.org/10.1097/TXD.0000000000001031 CR - Koç NS, Yıldırım T. COVID-19 Pandemisi Döneminde Transplantasyon, A. Renal Transplantasyon, Hacettepe Üniversitesi Tıp Fakültesi COVİD 19 Pandemi Raporu, 2020, sf:200-204. https://covid19.tubitak.gov.tr/sites/default/files/inline-files/covid19_pandemi_raporu.pdf ) CR - Kumar D, Manuel O, Natori Y, Egawa H, Grossi P, Han SH, Fernández-Ruiz M, Humar A. COVID-19: A global transplant perspective on successfully navigating a pandemic. Am J Transplant. 2020 Jul;20(7):1773-1779. https://doi.org/10.1111/ajt.15876 CR - Kurt HA, Alan C, Demirci E. COVID-19 ve böbrek nakli. Gürbüz R, editör. Üroloji ve COVID-19. 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.40-4. CR - Lentine KL, Mannon RB, Josephson MA. Practicing With Uncertainty: Kidney Transplantation During the COVID-19 Pandemic. Am J Kidney Dis. 2020-b Dec 31:S0272-6386(20)31191-4. https://doi.org/10.1053/j.ajkd.2020.12.003 CR - Lentine KL, Vest LS, Schnitzler MA, Mannon RB, Kumar V, Doshi MD, Cooper M, Mandelbrot DA, Harhay MN, Josephson MA, Caliskan Y, Sharfuddin A, Kasiske BL, Axelrod DA. Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era. Kidney Int Rep. 2020; 5(11): 1894-1905. https://doi.org/10.1016/j.ekir.2020.08.017 CR - López V, Vázquez T, Alonso-Titos J, Cabello M, Alonso A, Beneyto I, et al. Recommendations on management of the SARS-CoV-2 coronavirus pandemic (COVID-19) in kidney transplant patients. Nefrologia. 2020; https://doi.org/10.1016/j.nefro.2020.03.002 CR - Loupy A, Aubert O, Reese PP, Bastien O, Bayer F, Jacquelinet C. Organ procurement and transplantation during the COVID-19 pandemic. Lancet. 2020; 23: 395(10237):e95-e96. https://doi.org/10.1016/S0140-6736(20)31040-0 CR - Mahalingasivam V, Craik A, Tomlinson LA, Ge L, Hou L, Wang Q, Yang K, Fogarty DG, Keenan C. A A Systematic Review of COVID-19 and Kidney Transplantation. Kidney Int Rep. 2021; 6(1): 24-45. CR - Manzia TM, Angelico R, Toti L, Pisani G, Vita G, Romano F, et al. The hamletic dilemma of patients waiting for kidney transplantation during the COVID-19 pandemic: To accept or not to accept (an organ offer)? Transpl Infect Dis. 2021; 4: e13560. https://doi.org/10.1111/tid.13560 CR - Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, Manson JJ; HLH Across Speciality Collaboration, UK. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020; 28; 395(10229): 1033-1034. https://doi.org/10.1016/S0140-6736(20)30628-0 CR - Pascual J, Melilli E, Jiménez-Martín C, González-Monte E, Zárraga S, Gutiérrez-Dalmau A, et al. Spanish Society of Nephrology COVID-19 Group. COVID-19-related Mortality During the First 60 Days After Kidney Transplantation. Eur Urol. 2020; 78(4): 641-643. https://doi.org/10.1016/j.eururo.2020.06.036 CR - Pei G, Zhang Z, Peng J, Liu L, Zhang C, Yu C, Ma Z, Huang Y, Liu W, Yao Y, Zeng R, Xu G. Renal Involvement and Early Prognosis in Patients with COVID-19 Pneumonia. J Am Soc Nephrol. 2020; 31(6): 1157-1165. https://doi.org/10.1681/ASN.2020030276 CR - Pereira MR, Mohan S, Cohen DJ, Husain SA, Dube GK, Ratner LE, et al. COVID-19 in solid organ transplant recipients: Initial report from the US epicenter. Am J Transplant. 2020; 20(7): 1800-1808. https://doi.org/10.1111/ajt.15941 CR - Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020; 26; 323(20): 2052-2059. https://doi.org/10.1001/jama.2020.6775 CR - Tan EK, Koh YX, Kee T, Juhari JB, Tan TE, Sim DKL, et al. Waitlisted Transplant Candidates' Attitudes and Concerns Toward Transplantation During COVID-19. Ann Transplant. 2020; 8(25): e926992. https://doi.org/10.12659/AOT.926992 CR - Ulu S, Gungor O, Gok Oguz E, Hasbal NB, Turgut D, Arici M. COVID-19: a novel menace for the practice of nephrology and how to manage it with minor devastation?. Ren Fail. 2020;42(1):710-725. https://doi.org/10.1080/0886022X.2020.1797791 CR - Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARSCoV- 2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020;8(5):475-481. CR - Yılmaz R. COVID-19 ve böbrek transplantasyonu.Ateş K, Arıcı M, editörler. Nefroloji ve COVID-19. 1. Baskı. Ankara: Türkiye Klinikleri; 2020. p.47-51. UR - https://doi.org/10.52976/vansaglik.944910 L1 - https://dergipark.org.tr/tr/download/article-file/1795607 ER -