@article{article_951593, title={The Relationship Between Vitamin D Deficiency And CHA₂DS₂-VASc Score in Chronic Coronary Syndrome}, journal={The Medical Journal of Mustafa Kemal University}, volume={12}, pages={211–218}, year={2021}, DOI={10.17944/mkutfd.951593}, author={Türkoğlu, Caner and Genc, Omer}, keywords={Kronik Koroner Sendrom, D Vitamin, CHA2DS2-VASc Skoru}, abstract={Objective: To assess the relationship between Vitamin D level and CHA2DS2-VASc score in patients with chronic coronary syndrome (CCS). Methods:A total of 147 participants with CCS who underwent coronary angiography and had critical coronary artery stenosis were retrospectively enrolled in the study. Patients’ CHA2DS2-VASc scores were measured. Laboratory parameters including vitamin D and echocardiographic findings were recorded. Participants were divided into two groups according to CHA2DS2-VASc score, CHA2DS2-VASc score <3 as low-moderate group and CHA2DS2-VASc score ≥3 as high group. Results: Mean age was 62.7±10.5 and 80 (54.4%) were female. Age was older in the group with high CHA2DS2-VASc score (63.6±10.7 vs 56.6±6.3, p <0.001). Body mass index (BMI) and diabetes mellitus (DM) frequency were higher in the high score group (p=0.003 and p <0.001, respectively), whilst ejection fraction and vitamin D level were lower (p=0.02 and p <0.001, respectively). In multivariate logistic regression analysis with forward selection, BMI (OR: 1.383, 95% CI: 1.155-1.657, p <0.001) and Vitamin D level (OR: 0.852, 95% CI: 0.776-0.935, p=0.001) were independently associated with high CHA2DS2-VASc score. A cut-off value of 23.6 ng/ml for vitamin D level predicted high CHA2DS2-VASc score, with 61% sensitivity and 84% specificity [AUC:0.755 (0.678-0.822), %95 CI, p <0.001] in receiver operating characteristic (ROC) curve analysis. Conclusion: In patients with CCS undergoing coronary angiography, it was determined an independent relationship between low vitamin D levels and high CHA2DS2-VASc score.}, number={44}, publisher={Hatay Mustafa Kemal Üniversitesi}