TY - JOUR T1 - Effect of xanthogranulomatous cholecystitis on surgery TT - Ksantogranülomatöz kolesistitin cerrahi üzerine etkisi AU - Altıok, Merih AU - Kurt, Feyzi PY - 2021 DA - December Y2 - 2021 DO - 10.17826/cumj.976851 JF - Cukurova Medical Journal JO - Cukurova Med J PB - Çukurova Üniversitesi WT - DergiPark SN - 2602-3032 SP - 1351 EP - 1359 VL - 46 IS - 4 LA - en AB - Purpose: The aim of this study is to evaluate the incidence of pathologies causing biliary stasis together with xanthogranulomatous cholecystitis (XGC) and its effect on conversion to open cholecystectomy.Materials and Methods: This retrospective study reviewed the medical records of 11840 patients who underwent cholecystectomy at Seyhan State Hospital between January 2010 and June 2020. After examining the medical records, 40 (0.33%) of 11840 cholecystectomy cases were diagnosed as XGC pathologically.Results: In the last decade, 40 (0.33%) patients out of a total of 11840 patients who underwent cholecystectomy were diagnosed with XGC. The mean age of the cases was 58 (34-88). In 26 (65%) of 40 patients, surgery was completed laparoscopically. Open surgery was performed in 5 (12.5%) of them. Nine (22.5%) patients were converted from laparoscopic cholecystectomy to open surgery. In all cholecystectomy cases, the conversion cholecystectomy(CC) rate was 412/11840 (3.4%). Endoscopic retrograde cholangiopancreatography(ERCP) was performed in 13 (32.5%) patients for diagnosis and therapeutic purposes related to bile ducts. The gallbladder wall's average thickness was found to be 8.0 millimeters (± 3.87) on histopathological examination. 38 (95%) patients had an increase in gall bladder wall thickness of 4 millimeters or more. CC rate was found to be high in the subgroup analysis of pathology causing bile stasis and in patients who underwent emergency cholecystectomy.Conclusion: This study demonstrates that the pathologies causing bile stasis are observed more frequently in XGC patients than other cholecystitis patients, suggesting that these pathologies may be associated with XGC. KW - Conversion cholecystectomy KW - gallbladder KW - laparoscopy KW - xanthogranulomatous cholecystitis N2 - Amaç:. Bu çalışmada biliyer staza neden olan patolojilerin ksantogranülomatöz kolesistit (XGC) ile birlikte görülme sıklığı ve konversiyon kolesistektomiye etkisinin değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Bu retrospektif çalışmada Ocak 2010-Haziran 2020 tarihleri arasında Seyhan Devlet Hastanesi'nde kolesistektomi yapılan 11840 hastanın tıbbi kayıtları incelendi. Tıbbi kayıtlar incelendikten sonra patolojik olarak XGC tanısı alan hastalar çalışmaya dahil edildi.Bulgular: Son on yılda kolesistektomi yapılan toplam 11840 hastanın 40'ına (%0.33) XGC tanısı kondu. Olguların yaş ortalaması 58 (34-88) idi. 40 hastanın 26'sında (%65) ameliyat laparoskopik olarak tamamlandı. Bunların 5'ine (%12,5) açık cerrahi uygulandı. Dokuz (%22.5) hastada laparoskopik kolesistektomiden açık cerrahiye geçildi. Tüm kolesistektomi olgularında konversiyon kolesistektomi(KK) oranı 412/11840 (%3.4) idi. Safra yolları ile ilgili tanı ve tedavi amaçlı 13 (%32.5) hastaya endoskopik retrograd kolanjiyopankreatografi (ERCP) yapıldı. Histopatolojik incelemede safra kesesi duvar kalınlığı ortalama 8,0 milimetre (± 3,87) olarak bulundu. 38 (%95) hastada duvar kalınlığında 4 milimetre veya daha fazla artış vardı. Safra stazına neden olan patolojinin alt grup analizinde ve acil kolesistektomi yapılan hastalarda KK oranı yüksek bulundu.Sonuç: Bu çalışma ışığında XGC hastalarında safra stazına neden olan patolojilerin diğer kolesistit hastalarına göre daha sık görülmesi bu patolojilerin XGC etiyolojisi ile ilişkili olabileceğini düşündürmektedir. CR - 1. Jessurun J, Albores-Saavedra J. Gallbladder and extrahepatic biliary ducts. In: Damjanov I, Linder J (eds) Anderson's pathology. 2006;p:1859 CR - 2. Goodman ZD, Ishak KG. Xanthogranulomatous cholecystitis. Am J Surg Pathol. 1981;5:653–59 CR - 3. Guzman-Valdivia G. Xanthogranulomatous cholecystitis: 15 years experience. World J Surg. 2004;28:254–57 CR - 4. Park JW, Kim KH, Kim SJ, Lee SK. Xanthogranulomatous cholecystitis: Is an initial laparoscopic approach feasible? Surg Endosc. 2017;31:5289-94. CR - 5. Guzman-Valdivia G. Xanthogranulomatous cholecystitis in laparoscopic surgery. J Gastrointest Surg. 2005;9:494–7 CR - 6. Levy AD, Murakata LA, Abbott RM, Rohrmann CA. Jr From the archives of the AFIP. Benign tumors and tumorlike lesions of the gallbladder and extrahepatic bile ducts: radiologic-pathologic correlation. Armed Forces Institute of Pathology. Radiographics. 2002;22:387–413 CR - 7. Yang T, Zhang BH, Zhang J, Zhang YJ, Jiang XQ, Wu MC. Surgical treatment of xanthogranulomatous cholecystitis, experience in 33 cases. Hepatobiliary Pancreat Dis Int. 2007;6:504–8. CR - 8. Wang M, Zhang T, Zang L, Lu A, Mao Z, Li J, et al. Surgical treatment for xanthogranulomatous cholecystitis: a report of 74 cases. Surg Laparosc Endosc Percutan Tech. 2009;19:231–3. CR - 9. Sharma D, Babu R, Sood G, Kapoor G, Solanki RS, Thomas S. Xanthogranulomatous cholecystitis masquerading as malignancy with liver metastasis. ANZ J Surg. 2009;79:946–7. CR - 10. Qasaimeh GR, Matalqah I, Bakkar S, Al Omari A, Qasaimeh M. Xanthogranulomatous cholecystitis in the laparoscopic era is still a challenging disease. J Gastrointest Surg. 2015 Jun;19(6):1036-42. CR - 11. Krishna RP, Kumar A, Singh RK, Sikora S, Saxena R, Kapoor VK. Xanthogranulomatous inflammatory strictures of extrahepatic biliary tract: presentation and surgical management. J Gastrointest Surg. 2008 May;12(5):836-41. CR - 12. Kwon AH, Matsui Y, Uemura Y. Surgical procedures and histopathologic findings for patients with xanthogranulomatous cholecystitis. J Am Coll Surg. 2004;199:204–10 CR - 13. Duber C, Storkel S, Wagner PK, Muller J. Xanthogranulomatous cholecystitis mimicking carcinoma of the gallbladder: CT findings. J Comput Assist Tomogr. 1984; 8(6):1195–8. CR - 14. Christensen AH, Ishak KG. Benign tumors and pseudotumors of the gallbladder. Report of 180 cases. Arch pathol. 1970;5:423–32. CR - 15. Parra JA, Acinas O, Bueno J, Guezmes A, Fernandez MA, Farin as MC. Xanthogranulomatous cholecystitis: clinical, sonographic, and CT findings in 26 patients. AJR. 2000;174:979–83 CR - 16. Goshima S, Chang S, Wang JH, Kanematsu M, Bae KT, Federle MP. Xanthogranulomatous cholecystitis: diagnostic performance of CT to differentiate from gallbladder cancer. Eur J Radiol. 2010;74:79–83 CR - 17. Saritas AG, Gul MO, Teke Z, Ulku A, Rencuzogullari A, Aydin I, et al. Xanthogranulomatous cholecystitis: a rare gallbladder pathology from a single-center perspective. Ann Surg Treat Res. 2020;99:230-37. doi:10.4174/astr.2020.99.4.230 CR - 18. Yucel O, Uzun MA, Tilki M, Alkan S, Kilicoglu ZG, Goret CC, et al. Xanthogranulomatous Cholecystitis: Analysis of 108 Patients. Indian J Surg. 2017;79:510-14 CR - 19. Yildirim M, Oztekin O, Akdamar F, Yakan S, Postaci H. Xanthogranulomatous cholecystitis remains a challenge in medical practice: experience in 24 cases. Radiol Oncol. 2009;43:76–83 CR - 20. Srinivas GN, Sinha S, Ryley N, Houghton PW. Perfidious gallbladders—a diagnostic dilemma with xanthogranulomatous cholecystitis. Ann R Coll Surg Eng. 2007;89:168–72 CR - 21. Karabulut Z, Besim H, Hamamci O, Bostanoglu S, Korkmaz A. Xanthogranulomatous cholecystitis. Retrospective analysis of 12 cases. Acta Chir Belg. 2003;103:297–9 CR - 22. Han SH, Chen YL. Diagnosis and treatment of xanthogranulomatous cholecystitis: a report of 39 cases. Cell Biochem Biophys. 2012;64:131–5 CR - 23. Condilis N, Sikalias N, Mountzalia L, Vasilopoulos J, Koynnos C, Kotsifas T. Acute cholecystitis: when is the best time for laparoscopic cholecystectomy? Ann Ital Chir. 2008;79:23-7. CR - 24. Costantini R, Caldaralo F, Palmieri C, Napolitano L, Aceto L, Cellini C, et al. Risk factors for conversion of laparoscopic cholecystectomy. Ann Ital Chir. 2012;83:245-52 CR - 25. van der Velden JJ, Berger MY, Bonjer HJ, Brakel K, Laméris JS. Can sonographic signs predict conversion of laparoscopic to open cholecystectomy? Surg Endosc.1998;12:1232-5. CR - 26.Terho PM, Leppäniemi AK, Mentula PJ. Laparoscopic cholecystectomy for acute calculous cholecystitis: a retrospective study assessing risk factors for conversion and complications. World J Emerg Surg. 2016;16:11:54. CR - 27. Cui Y, Zhang H, Zhao E, Cui N, Li Z. Differential diagnosis and treatment options for xanthogranulomatous cholecystitis. Med Princ Pract. 2013;22:18–23 UR - https://doi.org/10.17826/cumj.976851 L1 - https://dergipark.org.tr/tr/download/article-file/1901304 ER -