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Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate

Year 2017, , 120 - 122, 01.09.2017
https://doi.org/10.5505/abantmedj.2016.43660

Abstract

Ectopic pregnancy is the most common cause of morbidity and mortality in the first trimester of pregnancy. Interstitial pregnancy is one of the rarest form of ectopic pregnancies that constitutes of 2-4% of ectopic pregnancies. In this paper, we discussed the case of the interstitial pregnancy that successfully treated with systemic Methotrexate without requiring operation. Serial β-hCG were regressed without any need to further manipulations including operation. According to our clinical experience, in cases of interstitial pregnancies that hemodynamically stabilized and not having severe abdominal nor pelvic pain, systemic MTX treatment could be applied under serial USG and β-hCG follow-ups, that contribute low morbidity and mortality rates and lesser requirement to surgical approach

References

  • 1. Anon, Ectopic pregnancies: United States, 1990-1992.MMWR Morb Mortal Wkly Rep 1995;44:46 48.
  • 2. Lau S, Tulandi T. Conservative medical and surgical management of interstitial ectopic pregnancy. Fertil Steril 1999;72:207-15.
  • 4. Kerr LM, Anderson DF. Angular pregnancy: A clinical entity. Br Med J 1934; 1: 1113-4
  • 5. Bond AL, Grifo JA, Chervenak FA. Term interstitial pregnancy with uterine torsion: sonographic, pathologic, and clinical findings. Obstet Gynecol 1989; 73: 857-9
  • 6. Stewart EA, Yeh J. The fallopian tubes and ectopic pregnancy. In: Ryan KJ, Berkowitz RS, Barbieri RL, editors. Kistner’s gynecology. 6th ed. St. Louis: Mosby-Year Book; 1995. p. 166-86.
  • 7. Maliha WE, Gonella P, Degnan EJ. Ruptured interstitial pregnancy presenting as an intrauterine pregnancy by ultrasound. Ann Emerg Med 1991; 20: 910-2
  • 8. Karsdorp VHM, Van der Veen F, Boer-Meisel ME, Kenemans P. Successful treatment with methotrexate of five interstiatial pregnancies. Hum Reprod 1992; 7:1164-9
  • 9. Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual pregnancy with a single methotrexate injection: a report of 3 cases. J Reprod Med 2005; 50: 141-4
  • 10. Deniz Balsak, Murat İnal, Yusuf Yıldırım, R. Soner Öner, Şivekar Tınar. Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. İnönü Üniversitesi Tıp Fakültesi Dergisi 14(1) 65- 67 (2007)

İnterstisyal Dış Gebelik Olgusunun Sistemik Metotreksat ile Başarılı Bir Şekilde Tedavisi

Year 2017, , 120 - 122, 01.09.2017
https://doi.org/10.5505/abantmedj.2016.43660

Abstract

Ektopik gebelik ilk trimesterde morbidite ve mortalitenin en sık nedenidir. İnterstisyal gebelik ektopik gebeliğin en nadir formlarından olup tüm ektopik gebeliklerin %2-4’ünü oluşturmaktadır. Bu yazımızda girişime gerek kalmadan sistemik Metotreksat ile başarılı şekilde tedavi edilmiş interstisyal gebelik olgusunu tartıştık. Seri β-hCG ölçümlerinde yeterli regresyon izlendi ve operasyona ihtiyaç kalmadı. Klinik deneyimimize göre hemodinamik olarak stabil, batında ve pelviste ağrısı olmayan interstisyal gebeliği olan hastalarda sistemik MTX tedavisi seri β-hCG ölçümleri ile izlem yapılarak uygulanması cerrahiye gereksinimi azaltmakta ve de böylece morbidite ve mortaliteye de olumlu yönde katkıda bulunmaktadır.

References

  • 1. Anon, Ectopic pregnancies: United States, 1990-1992.MMWR Morb Mortal Wkly Rep 1995;44:46 48.
  • 2. Lau S, Tulandi T. Conservative medical and surgical management of interstitial ectopic pregnancy. Fertil Steril 1999;72:207-15.
  • 4. Kerr LM, Anderson DF. Angular pregnancy: A clinical entity. Br Med J 1934; 1: 1113-4
  • 5. Bond AL, Grifo JA, Chervenak FA. Term interstitial pregnancy with uterine torsion: sonographic, pathologic, and clinical findings. Obstet Gynecol 1989; 73: 857-9
  • 6. Stewart EA, Yeh J. The fallopian tubes and ectopic pregnancy. In: Ryan KJ, Berkowitz RS, Barbieri RL, editors. Kistner’s gynecology. 6th ed. St. Louis: Mosby-Year Book; 1995. p. 166-86.
  • 7. Maliha WE, Gonella P, Degnan EJ. Ruptured interstitial pregnancy presenting as an intrauterine pregnancy by ultrasound. Ann Emerg Med 1991; 20: 910-2
  • 8. Karsdorp VHM, Van der Veen F, Boer-Meisel ME, Kenemans P. Successful treatment with methotrexate of five interstiatial pregnancies. Hum Reprod 1992; 7:1164-9
  • 9. Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual pregnancy with a single methotrexate injection: a report of 3 cases. J Reprod Med 2005; 50: 141-4
  • 10. Deniz Balsak, Murat İnal, Yusuf Yıldırım, R. Soner Öner, Şivekar Tınar. Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. İnönü Üniversitesi Tıp Fakültesi Dergisi 14(1) 65- 67 (2007)
There are 9 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Görker Sel This is me

Mehmet İbrahim Harma This is me

Müge Harma This is me

Aykut Barut This is me

İlker İnan Arıkan This is me

Publication Date September 1, 2017
Published in Issue Year 2017

Cite

APA Sel, G., Harma, M. İ., Harma, M., Barut, A., et al. (2017). Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate. Abant Medical Journal, 6(3), 120-122. https://doi.org/10.5505/abantmedj.2016.43660
AMA Sel G, Harma Mİ, Harma M, Barut A, Arıkan İİ. Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate. Abant Med J. September 2017;6(3):120-122. doi:10.5505/abantmedj.2016.43660
Chicago Sel, Görker, Mehmet İbrahim Harma, Müge Harma, Aykut Barut, and İlker İnan Arıkan. “Case Report of a Successful Treatment of Interstitial Pregnancy With Systemic Methotrexate”. Abant Medical Journal 6, no. 3 (September 2017): 120-22. https://doi.org/10.5505/abantmedj.2016.43660.
EndNote Sel G, Harma Mİ, Harma M, Barut A, Arıkan İİ (September 1, 2017) Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate. Abant Medical Journal 6 3 120–122.
IEEE G. Sel, M. İ. Harma, M. Harma, A. Barut, and İ. İ. Arıkan, “Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate”, Abant Med J, vol. 6, no. 3, pp. 120–122, 2017, doi: 10.5505/abantmedj.2016.43660.
ISNAD Sel, Görker et al. “Case Report of a Successful Treatment of Interstitial Pregnancy With Systemic Methotrexate”. Abant Medical Journal 6/3 (September 2017), 120-122. https://doi.org/10.5505/abantmedj.2016.43660.
JAMA Sel G, Harma Mİ, Harma M, Barut A, Arıkan İİ. Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate. Abant Med J. 2017;6:120–122.
MLA Sel, Görker et al. “Case Report of a Successful Treatment of Interstitial Pregnancy With Systemic Methotrexate”. Abant Medical Journal, vol. 6, no. 3, 2017, pp. 120-2, doi:10.5505/abantmedj.2016.43660.
Vancouver Sel G, Harma Mİ, Harma M, Barut A, Arıkan İİ. Case report of a Successful Treatment of Interstitial Pregnancy with Systemic Methotrexate. Abant Med J. 2017;6(3):120-2.