Rare occurrence of coexistent squamous cell carcinoma and basal cell carcinoma in a case of Xeroderma Pigmentosum

Yıl 2020, Cilt: 5 Sayı: 2, 90 - 92, 31.08.2020

Suguna Venugopal Aparna Muralidhar , Hemalata Mahantappa Sadaf Ahmad

https://doi.org/10.25000/acem.720032

Öz

Xeroderma Pigmentosum is an inherited disorder of DNA repair characterised by defective nucleotide excision repair, which is involved in repairing ultraviolet rays induced cross linking of pyramidine residues. Affected individuals are at increased risk of development of mucocutaneous cancers at a much earlier age than normal. This genodermatosis affects both sexes and all races. The incidence in India is still unknown. We report one such case of a nine year old boy with co-existent squamous cell carcinoma and basal cell carcinoma of the face.

Anahtar Kelimeler

Xeroderma Pigmentosum, DNA repair, Ultraviolet rays

Kaynakça

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