Pineal gland germinoma and pituitary insufficiency presenting with weight loss: Rare Case

Yıl 2023, Cilt: 2 Sayı: 1, 32 - 35, 30.01.2023

Emine Sena Sözen

https://doi.org/10.5505/achmedj.2023.76486

Öz

Intracranial germinomas are rare cancers that primarily affect
pediatric age group patients makingthem rarer still in adults. This
report presents a case of a primary intracranial germinoma arising in
the pineal region of a 24 year old male. The patient presented with a
history of weight loss and progressive vision loss secondary to
obstructive hydrocephalus. MRI demonstrated a large enhancing mass
lesion in the region of the pineal gland with radiological features
suggestive of a germinoma. Immunohistochemical stains confirmed
the histological diagnosis, with positive staining for C-Kit, OCT4 and
PLAP. In summary, this case report highlights that the diagnosis of
pineal gland germinoma present in a young male is made by
immunohistochemistry and detailed physical examination

Anahtar Kelimeler

Pineal Germinoma, Weight Loss, Pituitary Insufficiency