The Evaluation Of Dysmenorrhea, Quality Of Life, And Sexual Functions In Patients With And Without Conization

Year 2024, Volume: 3 Issue: 4, 146 - 151, 27.12.2024

Belma Gözde Özdemir

Abstract

INTRODUCTION: Conization is a surgical procedure performed to treat precancerous lesions. HPV is the most predisposing cause known. In our study, we aimed to evaluate and compare patients who were followed up as HPV positive and had conization due to cervical pathology in terms of dysmenorrhea, quality of life and sexual function.

METHODS:
HPV positive patients who underwent conization at Selcuk University Faculty of Medicine Obstetrics and Gynecology Department were evaluated.
4 main surveys were used in the study. Personal and Demographic Information Form, Dysmenorrhea Scale - Visual Analogue Scale (VAS), Female Sexual Function Index (FSFI); It was evaluated using (Turkish Female Sexual Function Scale), and European Organisation for Research and Treatment of Cancer Quality of Life (Turkish EORTC QLQ-C30 (version 3.0)). In our study, we considered two groups: those without hpv positive conization and those with hpv positive conization.

RESULTS: Dysmenorrhea scores of patients who underwent conization are higher than those of patients who did not undergo conization. Female sexual function scores of patients who underwent conization are higher than those of patients who did not undergo conization. There was no significant difference between the QoL scores of patients who underwent conization and those who did not.

DISCUSSION AND CONCLUSION: The cervix has an anatomically important neurovascular network. Care should be taken at this point in terms of conization procedures. Surgical complications should be carefully evaluated in the treatment of precancerous lesions. HPV is a sexually transmitted disease and the treatment of lesions caused by it can affect anxiety, quality of life, sexual function and menstrual cyclus.

Keywords

Conization, Dysmenorrhea, Leep, Sexual function, Quality of life

References

• 1) Furugori M, Asai-Sato M, Katayama K, Hirahara F, Miyagi E. Short- and long-term complications and the impact on quality of life after cervical conization by harmonic scalpel. J Obstet Gynaecol Res. 2017 Apr;43(4):749-757.
• 2) Kyrgiou M, Athanasiou A, Paraskevaidi M,et all. Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis. BMJ. 2016 Jul 28;354:i3633.
• 3) White J, Mason R, Lawen T, et all. Therapeutic Approaches to Penile Cancer: Standards of Care and Recent Developments. Res Rep Urol. 2023 Jun 2;15:165-174.
• 4) Ekmez M, Ekmez F. Effects of HPV Positivity in Women on Couples Sexual Behavior. J Sex Marital Ther. 2022;48(7):748-755.
• 5) Sadoun C, Ohannessian A, Carcopino X, et all. A. Impact de la conisation cervicale à l'anse diathermique sur la qualité de vie sexuelle [Impact of the loop electrosurgical excision procedure for cervical dysplasia on sexual function]. J Gynecol Obstet Biol Reprod (Paris). 2016 Feb;45(2):120-3. French. 6) Aygin, D. ve Eti Aslan, F. (2005). Kadın Cinsel İşlev Ölçeği'nin Türkçeye Uyarlaması. Turkiye Klinikleri J Med Sci., 25(3), 393-399.
• 7) Yaray O, Akesen B, Ocaklioğlu G, Aydinli U. Validation of the Turkish version of the visual analog scale spine score in patients with spinal fractures. Acta Orthop Traumatol Turc. 2011;45(5):353-8.
• 8) Demirci, Senem, et al. "Validation of the Turkish versions of EORTC QLQ-C30 and BR23 modules in breast cancer patients.” Asian Pacific Journal of cancer prevention: APJCP vol. 12,5 (2011): 1283-7.
• 9) Karimi Zarchi M, Mousavi A, Malekzadeh M, et all. Conservative treatment in young patients with cervical cancer: a review. Asian Pac J Cancer Prev. 2010;11(3):589-94
• 10) Karimi-Zarchi M, Mousavi A, Gilani MM, Barooti E, Miratashi-Yazdi A, Dehghani A. Conservative treatment in early cervical cancer. Int J Biomed Sci. 2013 Sep;9(3):123-8.
• 11) Vieira MA, de Araújo RLC, da Cunha Andrade CEM, Schmidt RL, Filho AL, Reis RD. A randomized clinical trial of a new anti-cervical stenosis device after conization by loop electrosurgical excision. PLoS One. 2021 Jan 20;16(1):e0242067.
• 12) Carter JE. Surgical treatment for chronic pelvic pain. JSLS. 1998 Apr-Jun;2(2):129-39.
• 13) Marinoff, S C, and M L Turner. “Vulvar vestibulitis syndrome.” Dermatologic Clinics vol. 10,2 (1992): 435-44.
• 14) Michaan N, Loboda N, Ochshorn I,et all. The Effect of Cervical Conization on Women's' Sexual Function and Psychological Health, A Prospective Observational Study. J Sex Med. 2022 Feb;19(2):257-262.
• 15) Litman EA, Cigna ST. Female Sexual Dysfunction in Women After Treatment of Cervical Dysplasia. Sex Med Rev. 2022 Jul;10(3):360-366.
• 16) Heinzler J, Brucker J, Bruckner et all. Impact of cervical dysplasia and its treatment on quality of life and sexual function. Arch Gynecol Obstet. 2018 Oct;298(4):737-745.
• 17) Kim BR, Kim MK, Kim YH. Effect of Loop Electrosurgical Excision Procedure on Sexual Dysfunction in Korean Women. J Korean Med Sci. 2023 May 8;38(18):e144.
• 18) Kilkku P, Grönroos M, Punnonen R. Sexual function after conization of the uterine cervix. Gynecol Oncol. 1982 Oct;14(2):209-12.
• 19) Nahidi M, Nahidi Y, Kardan G, Jarahi L, Aminzadeh B, Shojaei P, Fayyazi Bordbar MR. Evaluation of Sexual Life and Marital Satisfaction in Patients with Anogenital Wart. Actas Dermosifiliogr (Engl Ed). 2019 Sep;110(7):521-525. English, Spanish. doi: 10.1016/j.ad.2018.08.005. Epub 2019 Apr 10. PMID: 30981378.
• 20) Almonte M, Silva Idos S, Asare A, Gilham C, Sargent A, Bailey A, Turner A, Desai M, Kitchener HC, Peto J. Sexual behavior and HPV infection in British women, by postal questionnaires and telephone interviews. J Med Virol. 2011 Jul;83(7):1238-46. doi: 10.1002/jmv.22085. Epub 2011 Apr 22. PMID: 21520139.
• 21) Caruso S, Bruno MT, Cianci S, Di Pasqua S, Minona P, Cianci A. Sexual Behavior of Women With Diagnosed HPV. J Sex Marital Ther. 2019;45(7):569-573. doi: 10.1080/0092623X.2019.1586019. Epub 2019 Apr 11. PMID: 30836859.
• 22) Gilkey, Melissa B et al. “Provider communication and HPV vaccination: The impact of recommendation quality.” Vaccine vol. 34,9 (2016): 1187-92.