Case Report
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Year 2025, Volume: 4 Issue: 1, 34 - 37, 27.03.2025
https://doi.org/10.5505/achmedj.2025.30074

Abstract

References

  • 1. Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL et al. 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis. Thyroid. 2016 Oct;26(10):1343-1421.
  • 2. Ross DS. Syndromes of thyrotoxicosis with low radioactive iodine uptake. Endocrinol Metab Clin North Am. 1998;27(1):169–185.
  • 3. Moini J., Pereira K., Samsam M. Subacute Thyroiditis. In Epidemiology of Thyroid Disorders. 2020;7: 152.
  • 4. Yasuji I. Subacute thyroiditis in a patient with juvenile idiopathic arthritis undergoing etanercept treatment: a case report and review of the literature. Mod Rheumatol. 2013;23(2):397–400.
  • 5. Volpé R. The management of subacute (DeQuervain’s) thyroiditis. Thyroid. 1993;3(3):253–255.
  • 6. Zhao N, Wang S, Cui XJ, Huang MS, Wang SW, Li YG et al. Two-Years Prospective Follow-Up Study of Subacute Thyroiditis. Front Endocrinol (Lausanne). 2020 Feb 28;11:47.
  • 7. Görges J, Ulrich J, Keck C, Müller-Wieland D, Diederich S, Janssen OE. Long-term Outcome of Subacute Thyroiditis. Exp Clin Endocrinol Diabetes.2020 Nov;128(11):703-708. doi: 10.1055/a-0998-8035. Epub 2019 Sep 23. Erratum in: Exp Clin Endocrinol Diabetes. 2020 Nov;128(11):e1.
  • 8. Stagnaro-Green A, Schwartz A, Gismondi R, Tinelli A, Mangieri T, Negro R. High rate of persistent hypothyroidism in a large-scale prospective study of postpartum thyroiditis in southern Italy. J Clin Endocrinol Metab. 2011 Mar;96(3):652-7.
  • 9. Sencar ME, Calapkulu M, Sakiz D, Hepsen S, Kus A, Akhanli P et al. An Evaluation of the Results of the Steroid and Non-steroidal Anti-inflammatory Drug Treatments in Subacute Thyroiditis in relation to Persistent Hypothyroidism and Recurrence. Sci Rep. 2019 Nov 15;9(1):16899.
  • 10. Slatosky J, Shipton B, Wahba H. Thyroiditis: differential diagnosis and management. Am Fam Physician. 2000 Feb 15;61(4):1047-52, 1054. Erratum in: Am Fam Physician 2000 Jul 15;62(2):318.
  • 11. Singer PA. Thyroiditis. Acute, subacute, and chronic. Med Clin North Am. 1991 Jan;75(1):61-77.
  • 12. Hay ID. Thyroiditis: a clinical update. Mayo Clin Proc. 1985 Dec;60(12):836-43.
  • 13. Ray I, D’Souza B, Sarker P, Agarwal P. Management of Subacute Thyroiditis - A Systematic Review of Current Treatment Protocols. Int J Gen Med. 2022 Aug 6;15:6425-6439.

A rare case of subacute thyroiditis presenting as severe neck pain and otalgia

Year 2025, Volume: 4 Issue: 1, 34 - 37, 27.03.2025
https://doi.org/10.5505/achmedj.2025.30074

Abstract

Introduction: Subacute thyroiditis (de Quervain’s thyroiditis) is a clinical disorder characterized by inflammation of the thyroid tissue. It is the most common cause of painful thyroid disease. Although its etiology is not fully understood, it is mainly caused by viral infections.
Case: A 41-year-old male patient presented to the internal medicine outpatient clinic complaining of severe pain on the left side of the face and ear a few weeks after an upper respiratory tract infection. The pain started in the neck and spread to the jaw and ear. It was continuous and seemed to increase with head movements and chewing. On physical examination, the thyroid gland was palpable and several cervical lymph nodes less than 1 cm in diameter were found. In addition, all other findings on systemic physical examination and vital signs were normal.Laboratory data revealed the following: TSH level 0.02 mIU/L (N: 0.34-5.60mIU/L), free T4 level: 2.53 ng/dL (N: 0.61-1.48 ng/dL), free T3 level 6.42 ng/L (N: 2.3-4.2 ng/L), erythrocyte sedimentation rate (ESR) 67 mm/h (N: 0-20 mm/h), C-reactive protein level (CRP) 13.6 mg/dL (0-0.8 mg/dL). Thyroid ultrasonography was non-specific. Scintigraphic examination reported a marked decrease in thyroid activity, loss of contour clarity and lack of involvement of the thyroid parenchyma. Tc99m pertechnetate showed no uptake in the thyroid gland, and scintigraphic examination revealed subacute thyroiditis. Based on the patient’s physical examination and the laboratory and imaging studies performed on him, a diagnosis of subacute thyroiditis was made. Methylprednisolone was prescribed at a dose of 32 mg, which was gradually (The dose is reduced by half at one-week intervals) reduced and then discontinued at weekly follow-up visits after diagnosis. During th e follow-up period, notable improvement was observed in the patient’s laboratory values.

References

  • 1. Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL et al. 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis. Thyroid. 2016 Oct;26(10):1343-1421.
  • 2. Ross DS. Syndromes of thyrotoxicosis with low radioactive iodine uptake. Endocrinol Metab Clin North Am. 1998;27(1):169–185.
  • 3. Moini J., Pereira K., Samsam M. Subacute Thyroiditis. In Epidemiology of Thyroid Disorders. 2020;7: 152.
  • 4. Yasuji I. Subacute thyroiditis in a patient with juvenile idiopathic arthritis undergoing etanercept treatment: a case report and review of the literature. Mod Rheumatol. 2013;23(2):397–400.
  • 5. Volpé R. The management of subacute (DeQuervain’s) thyroiditis. Thyroid. 1993;3(3):253–255.
  • 6. Zhao N, Wang S, Cui XJ, Huang MS, Wang SW, Li YG et al. Two-Years Prospective Follow-Up Study of Subacute Thyroiditis. Front Endocrinol (Lausanne). 2020 Feb 28;11:47.
  • 7. Görges J, Ulrich J, Keck C, Müller-Wieland D, Diederich S, Janssen OE. Long-term Outcome of Subacute Thyroiditis. Exp Clin Endocrinol Diabetes.2020 Nov;128(11):703-708. doi: 10.1055/a-0998-8035. Epub 2019 Sep 23. Erratum in: Exp Clin Endocrinol Diabetes. 2020 Nov;128(11):e1.
  • 8. Stagnaro-Green A, Schwartz A, Gismondi R, Tinelli A, Mangieri T, Negro R. High rate of persistent hypothyroidism in a large-scale prospective study of postpartum thyroiditis in southern Italy. J Clin Endocrinol Metab. 2011 Mar;96(3):652-7.
  • 9. Sencar ME, Calapkulu M, Sakiz D, Hepsen S, Kus A, Akhanli P et al. An Evaluation of the Results of the Steroid and Non-steroidal Anti-inflammatory Drug Treatments in Subacute Thyroiditis in relation to Persistent Hypothyroidism and Recurrence. Sci Rep. 2019 Nov 15;9(1):16899.
  • 10. Slatosky J, Shipton B, Wahba H. Thyroiditis: differential diagnosis and management. Am Fam Physician. 2000 Feb 15;61(4):1047-52, 1054. Erratum in: Am Fam Physician 2000 Jul 15;62(2):318.
  • 11. Singer PA. Thyroiditis. Acute, subacute, and chronic. Med Clin North Am. 1991 Jan;75(1):61-77.
  • 12. Hay ID. Thyroiditis: a clinical update. Mayo Clin Proc. 1985 Dec;60(12):836-43.
  • 13. Ray I, D’Souza B, Sarker P, Agarwal P. Management of Subacute Thyroiditis - A Systematic Review of Current Treatment Protocols. Int J Gen Med. 2022 Aug 6;15:6425-6439.
There are 13 citations in total.

Details

Primary Language English
Subjects One Health
Journal Section Case Report
Authors

Serdar Olt 0000-0001-7023-1785

Yeşim Yıldırım 0000-0002-8424-7662

Publication Date March 27, 2025
Submission Date January 24, 2025
Acceptance Date February 16, 2025
Published in Issue Year 2025 Volume: 4 Issue: 1

Cite

EndNote Olt S, Yıldırım Y (March 1, 2025) A rare case of subacute thyroiditis presenting as severe neck pain and otalgia. ACH Medical Journal 4 1 34–37.