Relationship between Low Eosinophil Level at Presentation and Disease Severity and Mortality in Covid-19 Patients

Yıl 2022, Cilt: 13 Sayı: 2, 220 - 224, 15.03.2022

Elif Çelikel Afşin Kayıpmaz

https://doi.org/10.31067/acusaglik.988531

Öz

Amaç
Covid-19 tanısının erken ve hızlı tespit edilmesi mortaliteyi azaltmak için önemlidir. Eozinofil düzeyinin Covid-19 şüpheli vakalarda ilk başvuru anında düşük tespit edilmesinin hastalığın tanısını koymada ve ciddiyetini öngörebilmede kullanılabileceği belirtilmiştir. Çalışmamızda vakalarımızın eozinofil düzeyine bakarak bu parametrenin Covid-19 erken tanı ve tedavi planlanmasında kullanılabilirliğini saptamayı amaçladık.
Gereç ve Yöntem
Retrospektif olarak yapılan bu çalışmaya Covid-19 ön tanısı ile yatan vakaları aldık .Hastaların demografik özellikleri, laboratuar değerleri, radyolojik görüntüleri ve klinik takip bilgileri hastane bilgisayar sisteminden tarandı. SPSS 25 programı ile istatistik hesapları yapıldı.
Bulgular
Hastalarımızın 37’si kadındır (%30,08). Yaş ortalaması 49,13 ve en çok vakayı 26-65 yaş aralığında tespit ettik. En sık semptom olarak öksürük %51,21, dispne %26,8 ve ateş %26,39 görüldü. En sık görülen komorbid hastalık hipertansiyon %21,95 ve diyabet %12,19. Vakalarımızın %50,40’ın da (n:62) bilgisayarlı tomografisin de viral pnömoni (konsolüdasyon, buzlu cam opasiteleri), %49,59’unda (n:61) Polimeraz Zincir Reaksiyonu pozitifliği ve %39,02’sin de (n:48) ise hem bilgisayarlı tomografi’de viral pnömoni hem de PCR (+) tespit edildi. Vefat eden vakalarımızda ilk başvuruda eozinofil düzeylerinde düşüklüğü tespit ettik.
Sonuç
Eozinofil düzeyi düşüklüğü covid-19 şüpheli vakalarda tanıyı destekleyebilir ve klinik tablonun ciddi seyredebileceği ile ilgili bir uyarı olabilir.

Anahtar kelime: Covid-19, Eozinopeni, Mortalite




Abstract
Purpose
Early and rapid diagnosis of COVID -19 is vital to reduce mortality. It has been shown that detecting low eosinophil levels at the first application in suspected cases of COVID -19 can be used to diagnose the disease and predict its severity. In the present study, we aimed to determine the usability of this parameter in the early diagnosis of COVID-19 and treatment planning by evaluating at the eosinophil levels.
Methods
As a retrospective study included those who were admitted to the hospital, with the pre-diagnosis of COVID-19. Demographic characteristics, laboratory values, radiological images and clinical follow-up were scanned through the hospital system. All statistical analysis was done using the SPSS v25 software.
Result
Thirty-seven women (30.08%) were included in our study. The average age was 49.13, and we found the most cases in the 26-65 age range. The most common symptoms were cough 51.21%, dyspnea 26.8% and fever 26.39%. Hypertension was detected 21.95% and diabetes 12.19% as comorbid diseases. A computed tomography scan showed viral pneumonia in 50.40% (n:62) of our cases. 49.59% (n: 61) had Polymerase chain reaction positive results and 39.02% (n: 48) of our cases had both viral pneumonia in the CT scan and PCR (+). We found that dead patients had significant lower eosinophil levels.
Conclusion
eosinophil level may support the diagnosis in suspected cases of covid-19 and maybe a warning that the clinical picture may progress seriously.

Anahtar Kelimeler

Covid-19, Eosinopenia, Severity

Kaynakça

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