Epilepsi Hastalarında Uyku Bozuklukları: Anket Çalışması

Abstract

Amaç: Epilepsi ve uyku bozuklukları karşılıklı olarak birbirini olumsuz etkilemektedir. Bu çalışmanın amacı takibimizde olan epilepsi hastalarında sık görülen uyku bozukluklarını ve bu bozuklukların hastalık süresi, nöbet tipi ve sıklığı, antiepileptik ilaç (AEİ) sayısı ve türü ile ilişkisini incelemektir. Araçlar ve Yöntem: 99 epilepsi tanılı hasta bu anket çalışmamıza dahil edildi. Demografik veriler, epilepsi hastalık süresi, nöbet tipi ve sıklığı, kullanılan AEİ sayısı ve türü yüz yüze sorgulanarak kaydedildi. Tüm hastalara, Pittsburg uyku kalite indeksi (PUKİ), Epworth uykululuk ölçeği (EUÖ), Berlin uyku anketi (BUA) ve huzursuz bacaklar sendromu (HBS) anketi uygulandı. Bulgular: Epilepsi hastalarımızda PUKİ skoru 5 puan ve üzeri olan hasta sayısı 56 (%56.6), EUÖ skoru 10 puan ve üzeri olan hasta sayısı 9 (%9.1), BUA’ne göre obstrüktif uyku apne sendromu (OUAS) için yüksek riskli hasta sayısı 53 (%53.5) idi. Hastaların 25 (%25.3)’ inde HBS varlığı tespit edildi. PUKİ skoru jeneralize epilepsili hastalarda anlamlı yüksek (kötü uyku kalitesi) tespit edildi (p=0.045). PUKİ (p=0.035), EUÖ (p=0.043) ve BUA (p=0.039) skorlarının hepsi HBS var olan hastalarda, olmayanlara göre anlamlı yüksek idi. Sonuç: Hastalarımızda yüksek oranda HBS, kötü uyku kalitesi ve artmış OUAS riski bulundu. HBS' si olan epilepsi hastalarımızda, olmayanlara göre kötü uyku kalitesi, gündüz aşırı uykululuk ve OUAS riskini anlamlı yüksek bulundu. Epileptik bireylerde uyku bozukluklarının varlığının ısrarla sorgulanması gerektiğini düşünüyoruz.

Keywords

• epilepsi
• huzursuz bacaklar sendromu
• obstrüktif uyku apne sendromu
• uyku
• uyku kalitesi

Sleep Disorders in Epilepsy Patients: A Questionnaire Study

Abstract

Purpose: Epilepsy and sleep disorders mutually affect each other negatively. The aim of this study was to investigate the common sleep disorders in epilepsy patients in our follow-up and their relationship with disease duration, seizure type and frequency, number and type of antiepileptic drugs (AEDs). Materials and Methods: 99 patients diagnosed with epilepsy were included in this survey study. Demographic data, duration of epilepsy disease, seizure type and frequency, number and type of AEDs used were recorded by face-to-face questioning. Pittsburg sleep quality index (PSQI), Epworth sleepiness scale (ESS), Berlin sleep questionnaire (BSQ) and restless legs syndrome (RLS) questionnaire were applied to all patients. Results: In our epilepsy patients, the number of patients with a PDQI score of 5 points or more was 56 (56.6%), the number of patients with an IQR score of 10 points or more was 9 (9.1%), and the number of patients at high risk for obstructive sleep apnea syndrome (OSAS) according to BUA was 53 (53.5%). Conclusion: Our patients had a high rate of RLS, poor sleep quality and increased risk of OSAS. Poor sleep quality, excessive daytime sleepiness and OSAS risk were significantly higher in epilepsy patients with RLS compared to those without RLS. We think that the presence of sleep disorders in epileptic individuals should be questioned persistently.

Keywords

• epilepsy
• sleep
• sleep quality
• restless legs syndrome
• obstructive sleep apnea syndrome

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