Comparison of Magnesium Values in Functional Constipation and Control Patients

Abstract

Purpose: The objective of this study was to compare serum magnesium levels in patients with functional constipation against a control group. Materials and Methods: This retrospective study included patients diagnosed with functional constipation who presented to the pediatric gastroenterology outpatient clinic between 2021 and 2025. The diagnosis of functional constipation was based on the ROMA IV criteria. Results: A total of 757 patients' data were analyzed. The functional constipation group comprised 479 patients, while the control group included 278 patients. No significant difference was observed between the mean ages of patients in the functional constipation group (9.4±4.3 years) and control group (9.1±4.0 years) (P=0.525). The mean serum magnesium level for patients with functional constipation was 2.0±0.1 mg/dL, which was comparable to the mean level in the control group (2.0±0.1 mg/dL) (P=0.631). However, mean serum calcium levels were significantly higher in the functional constipation group (9.2±0.3 vs. 9.4±0.4; P=0.001).Among the patients with functional constipation, 266 (55.5%) had not received treatment prior to this study, whereas 217 (44.5%) had received treatment. There were no significant differences in the values of hemoglobin, platelet count, calcium, magnesium, sodium, and chloride between treated and untreated patients. Conclusion: It has been determined that magnesium and other electrolyte levels in patients with functional constipation are not different from those in the normal population. Prospective studies are needed to gain a more comprehensive understanding of the commonly seen functional constipation.

Keywords

• electrolytes
• functional constipation
• magnesium

Fonksiyonel Kabızlık ve Kontrol Hastalarında Magnezyum Değerlerinin Karşılaştırılması

Abstract

Amaç: Bu çalışmanın amacı fonksiyonel kabızlığı olan hastalarda serum magnezyum düzeylerini kontrol grubuyla karşılaştırmak amaçlanmıştır. Araçlar ve Yöntem: Bu retrospektif çalışmaya 2021-2025 yılları arasında pediatrik gastroenteroloji polikliniğine başvuran fonksiyonel kabızlık tanısı almış hastalar dahil edildi. Fonksiyonel kabızlık tanısı ROMA IV kriterlerine göre belirlendi. Bulgular: Toplam 757 hastanın verileri analiz edildi. Fonksiyonel kabızlık grubunda 479 hasta, kontrol grubunda ise 278 hasta vardı. Fonksiyonel kabızlık grubundaki hastaların ortalama yaşları (9.4±4.3 yıl) ile kontrol grubundaki hastaların ortalama yaşları (9.1±4.0 yıl) arasında anlamlı bir fark gözlenmedi (P=0.525). Fonksiyonel kabızlığı olan hastalarda ortalama serum magnezyum düzeyi 2.0±0.1 mg/dL idi ve bu değer kontrol grubundaki ortalama düzeye (2.0±0.1 mg/dL) benzerdi (P=0.631). Ancak, ortalama serum kalsiyum düzeyleri fonksiyonel kabızlık grubunda anlamlı derecede daha yüksekti (9.2±0.3'e karşı 9.4±0.4; P=0.001). Fonksiyonel kabızlığı olan hastalar arasında 266 (%55.5) kişi bu çalışmadan önce tedavi almamışken, 217 (%44.5) kişi tedavi almıştı. Tedavi gören ve görmeyen hastalar arasında hemoglobin, trombosit sayısı, kalsiyum, magnezyum, sodyum ve klorür değerlerinde anlamlı bir fark yoktu. Sonuç: Fonksiyonel konstipasyon hastalarının magnezyum ve diğer elektrolit düzeylerinin normal popülasyondan farklı olmadığı saptanmıştır. Yaygın görülen fonksiyonel konstipasyonun daha kapsamlı biçimde anlaşılabilmesi için ileriye dönük prospektif çalışmalara ihtiyaç vardır.

Keywords

• elektrolitler
• fonksiyonel kabızlık
• magnezyum

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