Akademik Gastroenteroloji Dergisi

1303-6629 2149-0600

Türk Gastroenteroloji Vakfı

10.17941/agd.1817440

Gastroenterology and Hepatology

Gastroenteroloji ve Hepatoloji

Hipertrigliseridemiye Bağlı Akut Pankreatitte Klinik Seyir ve Tedavi Yaklaşımları: 10 Yıllık Tek Merkez Deneyimi

Clinical Characteristics and Management of Hypertriglyceridemia-Associated Acute Pancreatitis: A Ten-Year Single Center Experience

https://orcid.org/0000-0003-2182-8598

Günegül

Yunus

SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ

https://orcid.org/0000-0003-1493-873X

Şenocak

İlyas Ethem

SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ

https://orcid.org/0000-0003-2786-432X

Ercan

Talha

SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ

https://orcid.org/0009-0000-3082-026X

Demiral

Yunus Emre

SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ Eminler

Ahmet Tarık

SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ

04 21 2026

25 1 54 63 11 05 2025 04 13 2026

2010

Akademik Gastroenteroloji Dergisi

Amaç:Bu çalışmada, hipertrigliseridemiye bağlı akut pankreatit (HTG-AP) olgularında klinik özellikler, tedavi yaklaşımları ve izlem sonuçlarının değerlendirilmesi amaçlanmıştır.Yöntem:Ocak 2015–Mayıs 2025 tarihleri arasında izlenen 76 HTG-AP hastasının (serum trigliserid düzeyi ≥500 mg/dL) verileri retrospektif olarak incelendi. Hastalar, Revize Atlanta Sınıflamasına göre hafif (n=43) ve orta–ağır (n=33) gruplara ayrıldı. Demografik, klinik ve laboratuvar veriler ile uygulanan tedavi protokolleri değerlendirildi.Bulgular:Hastaların yaş ortalaması 41.8±10.0 yıl olup %72.4’ü erkekti. Orta–ağır grupta ön-ceki pankreatit öyküsü (%72.7 vs. %53.5, p=0.04) ve tekrar atak oranı (%45.5 vs. %11.6, p=0.002) anlamlı olarak daha yüksekti. CRP düzeyleri belirgin biçimde yük-sek, albümin ve kalsiyum düzeyleri ise düşüktü (p

Background:This study aimed to evaluate the clinical characteristics, treatment strategies, and outcomes of patients with hypertriglyceridemia-induced acute pancreatitis (HTG-AP).Methods:Medical data of 76 patients with HTG-AP (serum triglyceride ≥500 mg/dL) admitted between January 2015 and May 2025 were retrospectively analyzed. Patients were classified as mild (n=43) or moderately-severe/severe (n=33) according to the Revised Atlanta Classification. Demographic, clinical, and laboratory parameters, as well as treatment protocols, were evaluated.Results:The mean age was 41.8±10.0 years, and 72.4% were male. Patients in the moderately severe to severe group had significantly higher rates of previous pancreatitis (72.7% vs. 53.5%, p=0.04) and recurrence (45.5% vs. 11.6%, p=0.002). CRP levels were significantly higher, while albumin and calcium levels were lower (p

Hipertrigliseridemi Akut pankreatit C-reaktif protein Albümin

Hypertriglyceridemia Acute pancreatitis C-reactive protein Albumin

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