A thyroid medullary carcinoma case presenting with chronic diarrhea

Yıl 2006, Cilt: 5 Sayı: 1, 72 - 76, 01.04.2006

Nil Özyüncü Ramazan İdilman Şahin Çoban Metin Kır Ali Özden

Öz

Medullary thyroid carcinoma is a neuroendocrine tumor, which accounts for 10% of thyroid cancers. It usually shows an indolent course, but can make lymphatic dissemination in early stages. Clinical symptoms are generally due to local invasion and hormonal secretion leading to flushing and diarrhea. Especially the sporadic forms are usually diagnosed late. We present a case who had been investigated in different centers for the etiology of intractable diarrhea for three years. The cause of the diarrhea was diagnosed as medullary thyroid carcinoma. We present the case to emphasize the importance of considering neuroendocrine tumors while searching for the etiology of diarrhea in gastroenterology.

Anahtar Kelimeler

Medullary thyroid carcinoma, diarrhea

Kronik diyare yakınması ile başvuran tiroid medüller karsinoma olgusu

Öz

Medüller tiroid karsinoma, tiroid kanserlerinin %10'unu teşkil eden nöroendokrin bir tümördür. Genelde yavaş seyirli bir tümör olmasına rağmen erken dönemde lenfatik disseminasyon gösterebilir. Klinik semptomlar genelde lokal invazyon ve hormon sekresyonuna bağlı ciltte kı- zarma ve diyare gibi semptomlardır. Özellikle sporadik formlar genelde daha geç tanı almaktadır. Burada sunacağımız olgu 3 yıl boyunca çeşitli farklı merkezlerde inatçı diyare nedeniyle etiyoloji araştırılması yapılmış bir hastadır. İshal sebebi medüller tiroid karsinoma olarak saptanan vaka, gastroenterolojide ishal etiyolojisi araştırılırken nöroendokrin tümörlerin de gözönüne alınmasının önemini vurgulamak için sunulmaktadır.

Anahtar Kelimeler

Medüller tiroid karsinoma, ishal

Kaynakça

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