Dynamic Shifts in Vitamin D Status Following Liposuction: Implications for Patient Monitoring and Health

Yıl 2024, , 1 - 4, 29.02.2024

Hüseyin Kandulu

https://doi.org/10.61845/agrimedical.1416520

Cited By: 1

Öz

Aim: Liposuction, a prevalent plastic surgery procedure, has gained a significant popularity in recent years. Vitamin D, a crucial fat-soluble vitamin, plays a vital role in numerous metabolic pathways, with emerging importance beyond skeletal health. This study aims to assess vitamin D status before and after liposuction surgery and examine the impact of removed adipose tissue on serum 25(OH)D levels. Material and Method: This cross-sectional study included patients undergoing liposuction between January 2022 and February 2023. Criteria for inclusion and evaluation of vitamin D status followed established guidelines. Vitamin D status and serum 25(OH)D levels were assessed and measured on the follow-up points. Results: Participants (n=21) exhibited a significant decrease in BMI postoperatively. Serum 25(OH)D levels showed a decline, reaching the lowest in the 1st month post-surgery. The distribution of vitamin D status shifted postoperatively, with an increased incidence of deficiency. Conclusion: The study underscores the dynamic relationship between BMI, adipose tissue, and vitamin D levels following liposuction. Research has associated vitamin D deficiency with adverse surgical outcomes and emphasizes the need for monitoring this parameter in elective surgeries. Findings suggest a dynamic shift in vitamin D status post-liposuction, advocating for continuous monitoring and potential supplementation.

Anahtar Kelimeler

Liposuction, Vitamin D, 25(OH)D, BMI, Adipose tissue, Surgical outcomes

Liposuction Sonrası D Vitamini Durumundaki Dinamik Değişimler: Hasta İzleme ve Sağlık Açısından Etkileri

Öz

Amaç: Yaygın bir plastik cerrahi işlemi olan liposuction son yıllarda önemli bir popülarite kazanmıştır. Yağda çözünen önemli bir vitamin olan D vitamini, iskelet sağlığının ötesinde önemi ortaya çıkan çok sayıda metabolik yolda hayati bir rol oynar. Bu çalışma, liposuction ameliyatı öncesi ve sonrası D vitamini durumunu değerlendirmeyi ve alınan yağ dokusunun serum 25(OH)D düzeyleri üzerindeki etkisini incelemeyi amaçlamaktadır. Gereç ve Yöntem: Bu kesitsel çalışmaya Ocak 2022 ile Şubat 2023 arasında liposuction uygulanan hastalar dahil edildi. D vitamini durumunun değerlendirilmesine ilişkin kriterler, yerleşik yönergelere uygun olarak yapıldı. Takip zamanlarında D vitamini durumu ve serum 25(OH)D düzeyleri değerlendirilip ölçüldü. Bulgular: Katılımcıların (n=21) ameliyat sonrası vücut kitle indeksinde anlamlı bir azalma olduğu görüldü. Serum 25(OH)D düzeyleri düşüş göstererek ameliyat sonrası 1. ayda en düşük seviyesine ulaştı. D vitamini durumunun dağılımı postoperatif dönemde değişti ve eksiklik gözlenen bireylerin insidansı arttı. Sonuç: Çalışma, liposuction sonrası vücut kitle indeksi, yağ dokusu ve D vitamini düzeyleri arasındaki dinamik ilişkinin altını çizmektedir. Araştırmalar, D vitamini eksikliğini olumsuz cerrahi sonuçlarla ilişkilendirmiştir ve elektif ameliyatlarda bu parametrenin izlenmesi ihtiyacını vurgulamaktadır. Bulgular, liposuction sonrası D vitamini durumunda dinamik bir değişim olduğunu ve sürekli takip ve ihtiyaç durumunda takviye gereksinimini desteklemektedir.

Anahtar Kelimeler

Liposuction, Vitamin D, 25(OH)D, VKİ, Adipoz doku, Cerrahi sonuçlar

Kaynakça

• Isaps International Survey On Aesthetic/Cosmetic Procedures performed in 2022. Available at: https://www.isaps.org/media/a0qfm4h3/isaps-global-survey_2022.pdf Accessed: 23.12.2023
• Iglar PJ, Hogan KJ. Vitamin D status and surgical outcomes: A systematic review. Patient Saf Surg. 2015;9:14.
• Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications. Chem Biol. 2014;21(3):319-29.
• Holick MF. Vitamin D status: measurement, interpretation, and clinical application. Ann Epidemiol. 2009;19(2):73-8.
• Amrein K, Scherkl M, Hoffmann M, et al. Vitamin D deficiency 2.0: an update on the current status worldwide. Eur J Clin Nutr. 2020;74(11):1498-1513.
• Sizar O, Khare S, Goyal A, et al. Vitamin D Deficiency. [Updated 2023 Jul 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www. ncbi.nlm.nih.gov/books/NBK532266/
• Álvarez-Mercado AI, Mesa MD, Gil Á. Vitamin D: Role in chronic and acute diseases. Encyclopedia of Human Nutrition. 2023:535-44.
• Chowdhury R, Kunutsor S, Vitezova A, et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ. 2014;348:g1903.
• Yeum KJ, Dawson-Hughes B, Joo NS. Fat mass is associated with serum 25-Hydroxyvitamin D concentration regardless of body size in men. Nutrients. 2018;10(7):850.
• Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911-30.
• Vimaleswaran KS, Berry DJ, Lu C, et al. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013;10(2):e1001383.
• Beckman LM, Earthman CP, Thomas W, et al. Serum 25(OH) vitamin D concentration changes after Roux-en-Y gastric bypass surgery. Obesity (Silver Spring). 2013;21(12):E599-606.
• Haider F, Ghafoor H, Hassan OF, Farooqui K, Bel Khair AOM, Shoaib F. Vitamin D and Cardiovascular Diseases: An Update. Cureus. 2023;15(11):e49734.
• Kaya MO, Pamukçu E, Yakar B. The role of vitamin D deficiency on COVID-19: A systematic review and meta-analysis of observational studies. Epidemiol Health. 2021;43:e2021074.
• Young MRI, Xiong Y. Influence of vitamin D on cancer risk and treatment: Why the variability? Trends Cancer Res. 2018;13:43-53.
• Cao M, He C, Gong M, Wu S, He J. The effects of vitamin D on all-cause mortality in different diseases: an evidence-map and umbrella review of 116 randomized controlled trials. Front Nutr. 2023;10:1132528.
• Lotfi-Dizaji L, Mahboob S, Aliashrafi S, Vaghef-Mehrabany E, Ebrahimi-Mameghani M, Morovati A. Effect of vitamin D supplementation along with weight loss diet on metainflammation and fat mass in obese subjects with vitamin D deficiency: A double-blind placebo-controlled randomized clinical trial. Clin Endocrinol (Oxf). 2019;90(1):94-101.
• Bandstein M, Schultes B, Ernst B, Thurnheer M, Schiöth HB, Benedict C. The Role of FTO and Vitamin D for the Weight Loss Effect of Roux-en-Y Gastric Bypass Surgery in Obese Patients. Obes Surg. 2015;25(11):2071-7.
• Dietary reference intakes for calcium and vitamin D, released November 30, 2010. Available at http://www.nationalacademies.org/hmd/∼/media/Files/Report Files/2010/Dietary- Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin D and Calcium 2010 Report Brief. pdf. Accessed 12.12.2023.
• Holick MF. Vitamin D status: measurement, interpretation, and clinical application. Ann Epidemiol. 2009;19(2):73-8.