Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery

Fulya Taktak

doi:10.5578/fmbd.26306

Araştırma Makalesi

Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery

Yıl 2016, Cilt: 16 Sayı: 1, 68 - 75, 30.04.2015

Fulya Taktak

https://doi.org/10.5578/fmbd.26306

Cited By: 5

Öz

In this study, poly(2‐dimethylamino)ethyl methacrylate (PDMAEMA) gels were prepared via in situ
polymerization reaction. Synthesized hydrogel was characterized with FTIR spectroscopy and SEM. The
pH‐ and temperature dependentswelling / deswelling behavior was investigated. The hydrogelshowed
highest value of swelling at pH 2. The rising temperature led to a decrease in swelling ratio due to the
fact that hydrophobic interactions between polymer segments become dominant. Furthermore, it was
observed that PDMAEMA hydrogel exhibited rapid deswelling rate in response to temperature and pH.
The drug release profile of PDMAEMA hydrogel has been reported by using Ibuprofen as a model drug.

Anahtar Kelimeler

Hydrogel, Controlled drug delivery, Rapid response, Deswelling

Toplam 0 adet kaynakça vardır.

Ayrıntılar

Konular	Mühendislik
Bölüm	Makaleler
Yazarlar	Fulya Taktak
Yayımlanma Tarihi	30 Nisan 2015
Gönderilme Tarihi	18 Mart 2016
Yayımlandığı Sayı	Yıl 2016 Cilt: 16 Sayı: 1

Kaynak Göster

APA	Taktak, F. (2015). Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, 16(1), 68-75. https://doi.org/10.5578/fmbd.26306
AMA	Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. Nisan 2015;16(1):68-75. doi:10.5578/fmbd.26306
Chicago	Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16, sy. 1 (Nisan 2015): 68-75. https://doi.org/10.5578/fmbd.26306.
EndNote	Taktak F (01 Nisan 2015) Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16 1 68–75.
IEEE	F. Taktak, “Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery”, Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, c. 16, sy. 1, ss. 68–75, 2015, doi: 10.5578/fmbd.26306.
ISNAD	Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 16/1 (Nisan 2015), 68-75. https://doi.org/10.5578/fmbd.26306.
JAMA	Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2015;16:68–75.
MLA	Taktak, Fulya. “Rapid Deswelling of PDMAEMA Hydrogel in Response to PH and Temperature Changes and Its Application in Controlled Drug Delivery”. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi, c. 16, sy. 1, 2015, ss. 68-75, doi:10.5578/fmbd.26306.
Vancouver	Taktak F. Rapid Deswelling of PDMAEMA Hydrogel in Response to pH and Temperature Changes and Its Application in Controlled Drug Delivery. Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi. 2015;16(1):68-75.