Diabetes mellitus (DM) is a progressive disorder which is defined as the deficiency in insulin secretion and abnormal glucose metabolism and is caused by metabolic incompatibilities. DM is one of the most commonly encountered diseases in primary care, according to the high prevalence rates (% 7).
Diabetes mellitus (DM) is a progressive disorder which is defined as the deficiency in insulin secretion and abnormal glucose metabolism and is caused by metabolic incompatibilities. DM is one of the most commonly encountered diseases in primary care, according to the high prevalence rates (% 7).
1. Standards of medical care in diabetes. American Diabetes Association. Diabetes Care. 2011. http://care.diabetesjournals.org/
content/34/Supplement_1/S11.full
2. Banerji M,Lebovitz H:Insulin sensitive and insulin resistant variants in IDDM.Diabetes,1989; 38:784-792.
3. Turner RC,Holman RR,Matthews D. et al.:Insulin deficiency and
insulin resistance interaction in diabetes :estimation of their
relatives contribution by feedback analysis from basal plasma insulin and glucose concentrations. Metabolism 1979;28:1086-
1096.
4. Diagnosis and Classification of Diabetes Mellitus, Diabetes Care
January 2009 vol. 32 no. Supplement 1 S62-S67.
5. Baekkeskov S,Neilsen JH,Marner B,Bilde T,Ludvigsson J,Lernmark
A:Autoantibodies in newly diagnosed diabetic children with
immunoprecipitate human pancreatic islet cell proteins.Nature1982; 298:167-169.
6. Myers MA,Rabin DU,RowleyMJ:Pancreatic islet cell cytoplasmic antibody in diabetes is represented by antibodies to isletcell antigen 512 and glutamic asid decarboxylase.Diabetes
,1995:44:1290-1295
8. Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type
2 diabetes mellitus by changes in lifestyle among subjects with
impaired glucose tolerance. N Engl J Med. 2001;344:1343-1348.
9. Holman RR, Paul SK, Bethel MA,et al. 10-year follow-up of
intensive glucose control in type 2 diabetes. N Engl J Med.
2008;359:1577-1589.
10. Nathan DM, Buse JB, Davidson MB, et al. Management of
hyperglycemia in type 2 diabetes:A consensus algorithm for the
initiation and adjustment of therapy: a consensus algorithm for
the initiation and adjustment of therapy: a consensus statement
of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2009;32:193-
199.
11. Rotella CM, Monami M, Mannucci E. Metformin beyond
diabetes:new life for an old drug. Curr Diabetes Rev 2006;2:
307-315,
12. UK Prospective Diabetes Study Group. Intensive blood-glucose
control with sulfonylureas or insulin compared with conventional tteatment and risk of complications in patients with type 2
diabetes, Lancet 1998;352:837-853.
13. Lebovitz HE. Therapy for diabetes mellitus and related disorders. 4. Ed. Virginia, Port City Press, 2004;192-197.
15. Gromada J, Rorsman P. Horm Metab Res. 2004;36:822–829.
16. DeFronzo R.A, Ratner E R, Han J, et al..Effects of exenatide on
glycemic control and weight over 30 weeks in metformine treated patients with type 2 diabetes. Diabetes care .2005;28:1092-
1100.
17. Cushman WC, Evans GW, et al. Effects of intensive bloodpressure control in type 2 diabetes mellitus. N Engl J Med.
2010;362:1575-1585.
Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması
Diabetes Mellitus (DM); insülin sekresyon defekti ve anormal glukoz metabolizması ile tanımlanan, metabolik bozuklukların yol açtığı ilerleyici bir hastalıktır. Yüksek prevalansı (% 7) nedeniyle birinci basamakta en sık karşılaşılan hastalıklardandır. DM, insülin hormon sekresyonunun ve/veya insüline karşı doku cevabının mutlak veya göreceli azlığı sonucu karbonhidrat, protein ve yağ metabolizmasında bozukluklara yol açan kronik hiperglisemik bir grup metabolizma hastalığıdır . American Diabetes Association (ADA) ‘ya göre, Tip 1, Tip 2, gestasyonel ve diğer spesifik tipler olarak sınıflandırılmaktadır. Tip 1 DM de mutlak insülin eksikliği varken, Tip 2 DM de insülin rezistansı ve rölatif bir insülin eksikliği vardır.1, , Diyabetik popülasyonun %10-20’si Tip 1 DM, %80-90’nı ise Tip 2 DM’dir.
1. Standards of medical care in diabetes. American Diabetes Association. Diabetes Care. 2011. http://care.diabetesjournals.org/
content/34/Supplement_1/S11.full
2. Banerji M,Lebovitz H:Insulin sensitive and insulin resistant variants in IDDM.Diabetes,1989; 38:784-792.
3. Turner RC,Holman RR,Matthews D. et al.:Insulin deficiency and
insulin resistance interaction in diabetes :estimation of their
relatives contribution by feedback analysis from basal plasma insulin and glucose concentrations. Metabolism 1979;28:1086-
1096.
4. Diagnosis and Classification of Diabetes Mellitus, Diabetes Care
January 2009 vol. 32 no. Supplement 1 S62-S67.
5. Baekkeskov S,Neilsen JH,Marner B,Bilde T,Ludvigsson J,Lernmark
A:Autoantibodies in newly diagnosed diabetic children with
immunoprecipitate human pancreatic islet cell proteins.Nature1982; 298:167-169.
6. Myers MA,Rabin DU,RowleyMJ:Pancreatic islet cell cytoplasmic antibody in diabetes is represented by antibodies to isletcell antigen 512 and glutamic asid decarboxylase.Diabetes
,1995:44:1290-1295
8. Tuomilehto J, Lindstrom J, Eriksson JG, et al. Prevention of type
2 diabetes mellitus by changes in lifestyle among subjects with
impaired glucose tolerance. N Engl J Med. 2001;344:1343-1348.
9. Holman RR, Paul SK, Bethel MA,et al. 10-year follow-up of
intensive glucose control in type 2 diabetes. N Engl J Med.
2008;359:1577-1589.
10. Nathan DM, Buse JB, Davidson MB, et al. Management of
hyperglycemia in type 2 diabetes:A consensus algorithm for the
initiation and adjustment of therapy: a consensus algorithm for
the initiation and adjustment of therapy: a consensus statement
of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2009;32:193-
199.
11. Rotella CM, Monami M, Mannucci E. Metformin beyond
diabetes:new life for an old drug. Curr Diabetes Rev 2006;2:
307-315,
12. UK Prospective Diabetes Study Group. Intensive blood-glucose
control with sulfonylureas or insulin compared with conventional tteatment and risk of complications in patients with type 2
diabetes, Lancet 1998;352:837-853.
13. Lebovitz HE. Therapy for diabetes mellitus and related disorders. 4. Ed. Virginia, Port City Press, 2004;192-197.
15. Gromada J, Rorsman P. Horm Metab Res. 2004;36:822–829.
16. DeFronzo R.A, Ratner E R, Han J, et al..Effects of exenatide on
glycemic control and weight over 30 weeks in metformine treated patients with type 2 diabetes. Diabetes care .2005;28:1092-
1100.
17. Cushman WC, Evans GW, et al. Effects of intensive bloodpressure control in type 2 diabetes mellitus. N Engl J Med.
2010;362:1575-1585.
Uğurlu, M., Üstü, Y., & Artantaş, A. (2012). Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması. Ankara Medical Journal, 12(3), 140-144.
AMA
Uğurlu M, Üstü Y, Artantaş A. Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması. Ankara Med J. Mart 2012;12(3):140-144.
Chicago
Uğurlu, Mehmet, Yusuf Üstü, ve Aylin Artantaş. “Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması”. Ankara Medical Journal 12, sy. 3 (Mart 2012): 140-44.
EndNote
Uğurlu M, Üstü Y, Artantaş A (01 Mart 2012) Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması. Ankara Medical Journal 12 3 140–144.
IEEE
M. Uğurlu, Y. Üstü, ve A. Artantaş, “Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması”, Ankara Med J, c. 12, sy. 3, ss. 140–144, 2012.
ISNAD
Uğurlu, Mehmet vd. “Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması”. Ankara Medical Journal 12/3 (Mart 2012), 140-144.
JAMA
Uğurlu M, Üstü Y, Artantaş A. Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması. Ankara Med J. 2012;12:140–144.
MLA
Uğurlu, Mehmet vd. “Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması”. Ankara Medical Journal, c. 12, sy. 3, 2012, ss. 140-4.
Vancouver
Uğurlu M, Üstü Y, Artantaş A. Diabetes Mellitus İçin Birinci Basamak Kullanımına Yönelik Kanıta Dayalı Bir Rehber Çalışması. Ankara Med J. 2012;12(3):140-4.