Research Article

Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions

Volume: 5 Number: 1 February 5, 2026

Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions

Abstract

Taraxacum officinale (Dandelion) is widely recognized in traditional medicine and the food industry. The plant, which is used for various purposes, is also popular as an herbal tea. Variations in tea preparation conditions have an impact on the phytochemical profile and biological activity. This study aims to evaluate and compare the phenolic profiles and antioxidant capacities of Taraxacum officinale infusions obtained by different brewing times. Infusions were prepared using different brewing times. The total phenolic content (TPC) and total flavonoid content (TFC) were quantified, and the phenolic profiles of the infusions were screened by LC-MS/MS. The antioxidant potential was assessed through DPPH radical scavenging activity and Ferric Reducing Antioxidant Power (FRAP) assays. Both total phenolic content (TPC) and total flavonoid content (TFC) increased with longer brewing periods. An increase in total phenolic and flavonoid contents with prolonged brewing time was accompanied by enhanced antioxidant activity. Chlorogenic acid, caffeic acid, luteolin-7-glucoside, and rutin were identified as the major phenolic compounds present in all infusion samples. The findings suggest that optimizing infusion parameters is essential for enhancing the availability of phenolic compounds.

Keywords

Taraxacum officinale, Phenolic profile, Antioxidant activity, LC-MS/MS

Ethical Statement

Ethical approval was not required for this study.

References

  1. [1] Baytop T. Bitkilerle Tedavi (Geçmişte ve Bugün). 1999, Nobel Tıp Kitabevleri, 227. [2] European Medicinal Agency-EMA (2009). Community herbal monograph on Taraxacum officinale Weber ex Wigg., folium. Accessed on 24.12.2025. https://www.ema.europa.eu/en/documents/herbal-monograph/finalcommunity-herbal-monograph-taraxacum-officinale-weber-ex-wigg-folium_en.pdf.
  2. [3] European Medicinal Agency-EMA (2021). European Union herbal monograph on Taraxacum officinale F.H. Wigg.,radix. Accessed on 24.12.2025. https://www.ema.europa.eu/en/documents/herbal-monograph/final-europeanunion-herbal-monograph-taraxacum-officinale-fh-wigg-radix_en.pdf
  3. [4] Liu L, Xiong H, Ping J, Ju Y, Zhang X. Taraxacum officinale protects against lipopolysaccharide-induced acute lung injury in mice. Journal of Ethnopharmacology, 2010; 130: 392–397.
  4. [5] He W, Han H, Wang W, Gao B. Anti-influenza virus effect of aqueous extracts from dandelion. Virology Journal, 2011; 8:538.
  5. [6] Mahesh A, Jeyachandran R, Cindrella L, Thangadurai D, Veerapur V, Muralidhara Rao D. Hepatocurative potential of sesquiterpene lactones of Taraxacum officinale on carbon tetrachloride-induced liver toxicity in mice. Acta Biologica Hungarica, 2010; 61: 175–190.
  6. [7] Park CM, Park JY, Noh KH, Shin JH, Song YS. Taraxacum officinale Weber extracts inhibit LPS-induced oxidative stress and nitric oxide production via the NF-κB modulation in RAW 264.7 cells. Journal of Ethnopharmacology, 2011; 133: 834–842.
  7. [8] García-Carrasco B, Fernández-Dacosta R, Dávalos A, Ordovás JM, Rodríguez-Casado A. In vitro Hypolipidemic and Antioxidant Effects of Leaf and Root Extracts of Taraxacum officinale. Medical Sciences 2015; 3: 38–54.
  8. [9] Díaz K, Espinoza L, Madrid A, Pizarro L, Chamy R. Isolation and Identification of Compounds from Bioactive Extracts of Taraxacum officinale Weber ex F. H. Wigg. (Dandelion) as a Potential Source of Antibacterial Agents. Evidence-Based Complementary and Alternative Medicine 2018: ID: 2706417.
  9. [10] Fan M, Zhang X, Song H, Zhang Y. Dandelion (Taraxacum Genus): A Review of Chemical Constituents and Pharmacological Effects. Molecules, 2023; 28: 5022. 11. Kania-Dobrowolska M, Baraniak J. Dandelion (Taraxacum officinale L.) as a Source of Biologically Active Compounds Supporting the Therapy of Co-Existing Diseases in Metabolic Syndrome. Foods, 2022; 11: 2858.
  10. [12] Epure A, Pârvu A, Vlase L, Benedec D, Hanganu D, Vlase AM, Oniga I. Polyphenolic Compounds, Antioxidant Activity and Nephroprotective Properties of Romanian Taraxacum offıcinale. Farmacia, 2022; 70 (1): 47-53.
APA
Can Agca, A., & Altay, D. (2026). Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions. Anatolian Journal of Pharmaceutical Sciences, 5(1), 33-44. https://doi.org/10.71133/anatphar.1857995
AMA
1.Can Agca A, Altay D. Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions. AJPS. 2026;5(1):33-44. doi:10.71133/anatphar.1857995
Chicago
Can Agca, Asli, and Derya Altay. 2026. “Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum Officinale Infusions”. Anatolian Journal of Pharmaceutical Sciences 5 (1): 33-44. https://doi.org/10.71133/anatphar.1857995.
EndNote
Can Agca A, Altay D (February 1, 2026) Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions. Anatolian Journal of Pharmaceutical Sciences 5 1 33–44.
IEEE
[1]A. Can Agca and D. Altay, “Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions”, AJPS, vol. 5, no. 1, pp. 33–44, Feb. 2026, doi: 10.71133/anatphar.1857995.
ISNAD
Can Agca, Asli - Altay, Derya. “Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum Officinale Infusions”. Anatolian Journal of Pharmaceutical Sciences 5/1 (February 1, 2026): 33-44. https://doi.org/10.71133/anatphar.1857995.
JAMA
1.Can Agca A, Altay D. Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions. AJPS. 2026;5:33–44.
MLA
Can Agca, Asli, and Derya Altay. “Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum Officinale Infusions”. Anatolian Journal of Pharmaceutical Sciences, vol. 5, no. 1, Feb. 2026, pp. 33-44, doi:10.71133/anatphar.1857995.
Vancouver
1.Asli Can Agca, Derya Altay. Comparison of Phenolic Profile and Antioxidant Activities of Taraxacum officinale Infusions. AJPS. 2026 Feb. 1;5(1):33-44. doi:10.71133/anatphar.1857995