ankem derg ANKEM Dergisi 1301-3114 2667-7652 ANKEM Antibiyotik ve Kemoterapi Derneği 10.54962/ankemderg.1861421 Bacteriology Clinical Microbiology Bakteriyoloji Klinik Mikrobiyoloji Evaluation of Antibiotic Resistence and Rectal Screening Findings in Enterococci ENTEROKOKLARDA ANTİBİYOTİK DİRENCİ VE REKTAL TARAMA BULGULARININ DEĞERLENDİRİLMESİ https://orcid.org/0000-0002-2904-8572 Yağci Burcu NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ https://orcid.org/0000-0003-3471-4768 Doğan Metin NECMETTİN ERBAKAN ÜNİVERSİTESİ, MERAM TIP FAKÜLTESİ 04 30 2026 40 1 16 24 01 12 2026 03 08 2026 Copyright © 1986, ANKEM Dergisi 1986 ANKEM Dergisi

Enterococci are clinically significant opportunistic pathogens due to their increasing frequency of isolation in hospital-acquired infections and their multidrug resistance characteristics. In this retrospective study, the distribution and antimicrobial resistance profiles of Enterococcus species isolated from various clinical samples, as well as vancomycin-resistant enterococcus (VRE) colonization detected in rectal swab screenings, were evaluated at the Necmettin Erbakan University Faculty of Medicine Hospital Medical Microbiology Laboratory between January 2023 and July 2025. A total of 4,295 Enterococcus spp. isolates were analyzed, with Enterococcus faecalis (54.1%) and Enterococcus faecium (44.7%) identified as the most frequently isolated species. The majority of isolates were recovered from urine (68.4%) and blood (17.7%) cultures. Regarding antimicrobial resistance, the lowest resistance rates were observed against linezolid (0.3%) and tigecycline (2.1%), whereas the highest resistance rates were detected against high-level gentamicin (61.4%) and ciprofloxacin (58.0%). E. faecium isolates exhibited significantly higher resistance rates to all tested antibiotics compared to E. faecalis(p

Enterokoklar, hastane kaynaklı enfeksiyonlarda giderek artan sıklıkta izole edilmeleri ve çoklu antibiyotik direnç özellikleri nedeniyle klinik açıdan önemli fırsatçı patojenlerdir. Bu retrospektif çalışmada, Ocak 2023–Temmuz 2025 tarihleri arasında Necmettin Erbakan Üniversitesi Tıp Fakültesi Hastanesi Tıbbi Mikrobiyoloji Laboratuvarı’nda çeşitli klinik örneklerden izole edilen Enterococcus türlerinin dağılımı ve antimikrobiyal direnç profilleri ile aynı döneme ait rektal sürüntü taramalarında saptanan vankomisine dirençli enterokok (VRE) kolonizasyonu retrospektif olarak değerlendirilmiştir. Toplam 4.295 Enterococcus spp. izolatı incelenmiş olup, en sık izole edilen türler Enterococcus faecalis (%54.1) ve Enterococcus faecium (%44.7) olarak belirlenmiştir. İzolatların çoğu idrar (%68.4) ve kan (%17.7) kültürlerinden elde edilmiştir. Antimikrobiyal direnç açısından en düşük direnç linezolid (%0.3) ve tigesikline (%2.1), en yüksek direnç ise yüksek düzey gentamisin (%61.4) ve siprofloksasine (%58.0) karşı saptanmıştır. E. faecium izolatlarının tüm antibiyotiklere karşı E. faecalis’e kıyasla anlamlı derecede daha yüksek direnç gösterdiği belirlenmiştir (p

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