ata diş hek fak derg Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 1300-9044 2667-5161 Atatürk Üniversitesi 10.17567/ataunidfd.419021 Health Care Administration Sağlık Kurumları Yönetimi ORAL SKUAMÖZ HÜCRELİ KARSİNOM: 3 OLGU SUNUMU VE LİTERATÜR DERLEMESİ Polat Akmansoy Berceste -namdar Pekiner Filiz - Dönmez Şakır Merve Alatlı Canan 04 22 2018 28 2 239 244 05 17 2016 07 01 2016 Copyright © 1986, Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi 1986 Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

Skuamöz hücrelikarsinom,  oral kavitede en sık izlenenmalignitedir. Ağız mukozasının  herbölgesinde görülebilen bu karsinomlarda tütün ve alkol tüketimi önemlietkendir. Bu makalede son altı ay içinde kliniğimizde tanısı konan,lokalizasyonları bakımından farklı üç oral skuamöz hücreli karsinom olgusuliteratür bilgileri doğrultusunda sunulmuştur.Anahtar kelimeler: Skuamöz hücrelikarsinom,  oral kavitede en sık izlenenmalignitedir. Ağız mukozasının  herbölgesinde görülebilen bu karsinomlarda tütün ve alkol tüketimi önemlietkendir. Bu makalede son altı ay içinde kliniğimizde tanısı konan,lokalizasyonları bakımından farklı üç oral skuamöz hücreli karsinom olgusuliteratür bilgileri doğrultusunda sunulmuştur.Anahtar kelimeler: Skuamöz hücreli karsinom, oral kavite,dişeti mukozası, dil mukozası ORAL SQUAMOUS CELL CARCINOMA: 3 CASE  REPORT AND REVIEW OF LITERATUREABSTRACTSquamous cellcarcinoma is the most common malignancy affecting the oral cavity. Tobacco andalcohol consumption in these carcinomas can be seen in every region where theoral mucosa is an important factor. This article in the latest issue of ourclinic diagnosed within six months in terms of localization of three differentoral squamous cell carcinoma are presented in accordance with the literature.Key words: Squamous cell carcinoma, oral cavity, gingiva,, tongueORAL SQUAMOUS CELL CARCINOMA: 3 CASE  REPORT AND REVIEW OF LITERATUREABSTRACTSquamous cellcarcinoma is the most common malignancy affecting the oral cavity. Tobacco andalcohol consumption in these carcinomas can be seen in every region where theoral mucosa is an important factor. This article in the latest issue of ourclinic diagnosed within six months in terms of localization of three differentoral squamous cell carcinoma are presented in accordance with the literature.Key words: Squamous cell carcinoma, oral cavity,gingiva, tongue

 Squamous cell carcinoma oral cavity gingiva Yalçın ED, Süslü N, Avcu N. Retromolar trigon skuamöz hücreli karsinom: Olgu sunumu. Atatürk Üniv.Diş Hek.Fak.Derg. 2014;supplement 9;1-5. 2. Bektaş-Kayhan K, Ünür M. Ağız boşluğunda görülen kanserler ve sınıflandırılması. İstanbul Üniversitesi Diş Hekimliği Fakültesi Dergisi 2011; 45:55-63. 3. Özbayrak S, Pekiner FN. Ağız Kanserleri- Erken tanı bakımından dişhekimliği, 1.Baskı İstanbul Quintessence Yayıncılık Ltd.Şti: 2016. p.21-28,65-74,151-157. 4. Haksever M. Oral Kavite Kanserlerinde Evreleme, Prognostik Faktörler ve Evreleme Sistemi Üzerine Değerlendirmeler Kocatepe Tıp Dergisi 2013;14: 109-17. 5. Audre K, Schraub S, Mercier M, Bontemps P. Role of alcohol and tobacco in the aetiology of head and neck cancer:A case-control study in the Doubs region of France. Eur J Cancer B Oral Oncol 1995;31B: 301-9. 6. Castellsague X, Quintana MJ, Martinez MC, et al. The role of type of tobacco and type of alcoholic beverage in oral carcinogenesis. Int J Cancer 2004;108: 741-9. 7. Chen PC, Kuo C, Pan CC, Chou MY. Risk of oral cancer associated with human papillomavirus infection, betel quid chewing, and cigarette smoking in Taiwan- an integrated molecular and epidemiological study of 58 cases. J Oral Pathol Med 2002;31: 317-22. 8. da Silva ID, Cerri A, Weckx LL. Prevalence of human papillomavirus in squamous cell carcinoma of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104: 497-500. 9. Figuero Ruiz E, Carretero Peláez MA, Cerero Lapiedra R, et al. Effects of the consumption of Alcohol in the oral cavity: Relationship with oral cancer. Med Oral 2004;9:14-23. 10. Gillison ML. Current topics in the epidemiology of oral cavity and oropharyngeal cancers. Head and Neck 2007;29: 779-92. 11. Jovanovic A, Schulten EA, Kostense PJ, et al. Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma. J Oral Pathol Med 1993,22: 459-62. 12. Morse DE, Psoter WJ, Cleveland D, Cohen D, Mohit-Tabatabai M, Kosis DL, et al. Smoking and drinking in relation to oral cancer and oral epithelial dysplasia. Cancer Causes Control 2007;18:919–29. 13. Neville BW, Day TA. Oral cancer and precancerous lesions. CA Cancer J Clin 2002;52: 195-215. 14. Özbayrak S. Ağız Hastalıkları Atlası Tanı Kriterleri, Ayırıcı Tanı ve Tedavi Yaklaşımları. 3. Baskı, İstanbul, Quintessence Yayıncılık Ltd.Şti.:2010. P.116-120 15. Öztürk B, Coşkun U, Yaman E, Kaya AO, Yıldız R, Benekli M, Büyükberber S. Oral Kavite Kanserlerinde Risk Faktörleri, Premalign Lezyonlar ve Kemoprevensiyon. Uluslararası Hematoloji-Onkoloji Dergisi 2009; 19:117-26. 15. Pintos J, Black MJ, Sadeghi N, et al. Human papillomavirus infection and oral cancer: A casecontrol study in Montreal, Canada. Oral Oncol 2008;44: 242-50. 17. Scuibba JJ. Oral cancer. The importance of early diagnosis and treatment. Am J Clin Dermatol 2001;2:239-51. 18. Seoane J, Van der Waal I, Van der Waal RI, Cameselle-Teijeiro J, Antón I, Tardio A, Alcázar-Otero JJ, Varela-Centelles P, Diz P. Metastatic tumours to the oral cavity: a survival study with a special focus on gingival metastases. J Clin Periodontol. 2009;36:488-92. 19. Tandon S, Tudur-Smith C, Riley RD, Boyd MT, Jones TM. A systematic review of p53 as a prognostic factor of survival in squamous cell carcinoma of the four main anatomical subsites of the head and neck. Cancer Epidemiol Biomarkers Prev 2010;19:574–87. 20. Weijers M, Snow GB, Bezemer DP, van dr Wal JE, van der Waal I. The status of the deep surgical margins in tongue and floor of mouth squamous cell carcinoma and risk of local recurrence; an analysis of 68 patients. Int J Oral Maxillofac Surg. 2004;33:146-49. 21. Bagan J, JimenezY, Fernandez J, et al: Malignant transformation of proliferative verrucous leukoplakia to oral squamous cell carcinoma: a series of 55 cases. Oral Oncol 2011;47:732-35. 22. Hashibe M, Jacob BJ, Thomas G, Ramadas K, Mathew B, Sankaranarayanan R, Zhang ZF. Socioeconomic status, lifestyle factors and oral premalignant lesions. Oral Oncology 2003; 39; 664-71. 23. Bettendorf O, Piffko J, Bankfalvi A. Prognostic and predictive factors in oral squamous cell cancer: important tools for planning individual therapy? Oral Oncology, 2004;40:110-19. 24. Napier SS, Speight PM: Natural history of potentially malignant oral lesions and conditions: An overview of the literature. J Oral Pathol Med 2008;37:1-10. 25. Sciubba JJ. Oral cancer the importance of early diagnosis and treatment. Am J Clin Dermatol, 2000;2:239-63.