atljm

Atlas Journal of Medicine

3023-6878 2791-7495

Atlas Üniversitesi

10.54270/atljm.2024.52

Health Services and Systems (Other)

Sağlık Hizmetleri ve Sistemleri (Diğer)

NAR KABUĞUNUN SAĞLIĞI GELİŞTİRİCİ VE HASTALIK ÖNLEYİCİ AKTİVİTESİ

HEALTH-IMPROVING AND DISEASE PREVENTIVE ACTIVITY OF POMEGRANATE PEEL

https://orcid.org/0000-0003-3664-9066

Koçak

Betül

ISTANBUL ATLAS UNIVERSITY

https://orcid.org/0000-0001-9632-9908

Yoldaş

Kardelen

ISTANBUL ATLAS UNIVERSITY

06 03 2024

4 10 101 108 07 31 2023 12 21 2023

2021

Atlas Journal of Medicine

Nar kabuğu, potansiyel sağlık yararları ile birlikte güçlü antioksidan aktivite içerir. Nar kabuğunun, polifenol bakımından zengin olması nedeniyle antikanser potansiyelinin araştırıldığı çalışmalar mevcuttur. Nar kabuğunun, in vitro, in vivo ve klinik deneylerde farklı kanser hücre dizileri üzerinde antiproliferatif etkiler göstermiştir. Bu derlemenin amacı nar kabuğunun çeşitli kanser hastalıklarına karşı fonksiyonel özelliklerini ve tıbbi faydalarını değerlendirmektir. Ek olarak, nar kabuğunun in vitro ve in vivo insan ve hayvan klinik deneylerinde kullanımının çeşitli sağlık sorunları üzerine etkisine de yer verilmiştir. Mevcut veriler, Punica granatum (nar) kabuğunun bazı hastalık durumlarının gelişmesinde engelleyici ve potansiyel terapötik olarak kullanılabileceğini ve insan sağlığına fayda sağladığını göstermektedir. Bu derlemede nar kabuğunun potansiyel sağlık yararları, geleneksel tıbbi tedavide kullanımı ve kanser ilerlemesini engelleme mekanizması vurgulanmıştır.

Pomegranate peel contains powerful antioxidant activity along with potential health benefits. There are studies investigating the anticancer potential of pomegranate peel because it is rich in polyphenols. Pomegranate peel has shown antiproliferative effects on different cancer cell lines in in vitro, in vivo and clinical trials. The purpose of this review is to evaluate the functional properties and medicinal benefits of pomegranate peel against various cancer diseases. In addition, the effects of the use of pomegranate peel in in vitro and in vivo human and animal clinical trials on various health problems are also included. Available data indicate that Punica granatum (pomegranate) peel can be used as an inhibitory and potential therapeutic in the development of some disease conditions and benefits human health. This review highlights the potential health benefits of pomegranate peel, its use in traditional medical therapy, and its mechanism of inhibiting cancer progression.

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