IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)

İbrahim Geçibesler

doi:10.18038/aubtda.284496

EN

IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)

Abstract

Tanacetum L. (Asteraceae) species have been used by local people in folk medicine for centuries in Turkey to treat antipyretic, headache, tinnitus, dizziness and against difficulties in childbirth. We performed detailed biological activity screening tests of Tanacetum abrotanifolium, collected from its natural habitats in the eastern region of Turkey, for the first time. To obtain active compound from aerial parts of T. abrotanifolium by using chromatographic techniques, anticancer, antimicrobial and antioxidant assays were applied. Total phenol, flavonoid, β-carotene and lycopene contents were determined quantitatively. The isolation procedure was carried out successfully through thin layer and column chromatographies. Bioactivity-guided fractionation led to the isolation of luteolin-7-O-glucoside, an agent of anticancer, antimicrobial and antioxidant. This active compound was isolated from aerial parts of T. abrotanifolium for the first time.

Keywords

Tanacetum abrotanifolium,luteolin-7-O-glucoside,anticancer activity,antimicrobial potency

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Details

Primary Language

English

Subjects

Engineering

Journal Section

-

Authors

İbrahim Geçibesler
BİNGÖL ÜNİVERSİTESİ, SAĞLIK YÜKSEKOKULU, HEMŞİRELİK BÖLÜMÜ
Türkiye

Publication Date

June 30, 2017

Submission Date

January 6, 2017

Acceptance Date

-

Published in Issue

Year 2017 Volume: 18 Number: 2

DOI

https://doi.org/10.18038/aubtda.284496

IZ

https://izlik.org/JA98DB26DL

APA

Geçibesler, İ. (2017). IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE). Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering, 18(2), 439-455. https://doi.org/10.18038/aubtda.284496

AMA

1.Geçibesler İ. IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE). AUJST-A. 2017;18(2):439-455. doi:10.18038/aubtda.284496

Chicago

Geçibesler, İbrahim. 2017. “IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)”. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering 18 (2): 439-55. https://doi.org/10.18038/aubtda.284496.

EndNote

Geçibesler İ (June 1, 2017) IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE). Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering 18 2 439–455.

IEEE

[1]İ. Geçibesler, “IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)”, AUJST-A, vol. 18, no. 2, pp. 439–455, June 2017, doi: 10.18038/aubtda.284496.

ISNAD

Geçibesler, İbrahim. “IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)”. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering 18/2 (June 1, 2017): 439-455. https://doi.org/10.18038/aubtda.284496.

JAMA

1.Geçibesler İ. IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE). AUJST-A. 2017;18:439–455.

MLA

Geçibesler, İbrahim. “IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE)”. Anadolu University Journal of Science and Technology A - Applied Sciences and Engineering, vol. 18, no. 2, June 2017, pp. 439-55, doi:10.18038/aubtda.284496.

Vancouver

1.İbrahim Geçibesler. IN VITRO BIOLOGICAL ACTIVITY STUDIES ON TANACETUM ABROTANIFOLIUM (L.) DRUCE (ASTERACEAE). AUJST-A. 2017 Jun. 1;18(2):439-55. doi:10.18038/aubtda.284496

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