Ionization and phonon production by $^{10}$B ions in radiotherapy applications

Yıl 2023, Cilt: 65 Sayı: 1, 30 - 37, 03.06.2023

Fatih Ekinci

https://doi.org/10.33769/aupse.1170687

Öz

The therapeutic use of heavy ions has received much attention due to
their physical and radiobiological properties. Thanks to these features of heavy ion
radiotherapy, radiation in tissues close to critical tissues can reduce LET while
allowing an increase in LET in tumors. Selection of biomaterials closest to the tissue
is critical to measure the accuracy of this LET transfer. The accuracy of LET and
radiological features measured in phantoms created from biomaterials selected
according to the characteristics of the target tissue is very important for human life.
For this reason, the research of polymeric materials, which is the closest biomaterial
to soft tissue and therefore phantom material, has increased recently. In this study,
ionization to the polymeric biomaterials closest to the soft tissue in boron therapy
application, and phonon release from all interactions were investigated and
analyzed. This analysis was performed using MC-based TRIM simulation. In the
analysis, the Bragg peak range closest to the soft tissue was 7.2% and PMMA was
the phonon release from all interactions. It has been observed that the phonon
production in phantoms results from ions on average 30% and recoils interactions
70%. The main novelty that this study will provide to the literature is to consider
the phonon interactions as well as the ionization interactions. Thus, apart from
proton and carbon, the most ideal polymeric biomaterial to be used instead of soft
tissue was evaluated by calculating all interactions. Thus, it is aimed to determine
the most ideal phantom material.

Anahtar Kelimeler

B ion treaphy, polimeric biomaterials, Bragg cure, phonon, TRIM Monte Carlo

Destekleyen Kurum

none

Proje Numarası

none

Kaynakça

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