Research Article

The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery

Volume: 76 Number: 3 June 30, 2024
TR EN

The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery

Abstract

Objectives: This study aims to identify clinical parameters beyond recurrent laryngeal nerve (RLN) anatomy contributing to loss of signal (LOS) during thyroid surgery. Materials and Methods: We retrospectively analyzed the records of 171 initial thyroid surgery patients under intraoperative nerve monitoring (IONM) by a single surgeon. Patient characteristics, surgical details, and LOS data were recorded. All surgical procedures were performed using intermittent IONM in accordance with international guideline statements. Patients were categorized according to the presence of LOS (LOS+ and LOS-), and logistic regression analysis was used to identify LOS-related factors. Results: Among 171 patients, 8 (4.7%) experienced LOS. LOS+ cases showed significantly lower tumor/nodule size and thyroid volume. No significant differences were observed in other variables between the LOS+ and LOS- groups. Logistic regression analysis identified tumor/nodule size ≤10 mm (p=0.006) and thyroid volume ≤12 mL (p=0.013) as significant factors. In 8 LOS+ patients, traction injuries were prevalent (87.5%), mainly at the level of Berry’s ligament, left-sided, and single-branch nerve anatomy in 87.5%. Complete recovery of LOS occurred in 37.5% of LOS+ cases after the termination of traction. Conclusion: Small thyroid volume increases the risk of the development of LOS, due to excessive RLN stretching during surgery. Our findings highlight the importance of minimizing traction and using continuous IONM to prevent LOS and subsequent vocal cord paralysis. Key Words: Thyroidectomy, Electromyography, Vocal Cord Paralysis, Loss of Signal, Intraoperative Neuromonitoring

Keywords

Ethical Statement

This study has been approved by the Ankara University Faculty of Medicine, Human Research Ethics Committee (decision no: İ07-506-23, date: 21.08.2023).

References

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  4. 4. Schneider R, Sekulla C, Machens A, et al. Postoperative vocal fold palsy in patients undergoing thyroid surgery with continuous or intermittent nerve monitoring. Br J Surg. 2015;102:1380-1387.
  5. 5. Lian T, Leong D, Ng K, et al. A Prospective Study of Electromyographic Amplitude Changes During Intraoperative Neural Monitoring for Open Thyroidectomy. World J Surg. 2023;47:1971-1977.
  6. 6. Liu N, Chen B, Li L, et al. Mechanisms of recurrent laryngeal nerve injury near the nerve entry point during thyroid surgery: A retrospective cohort study. Int J Surg. 2020;83:125-130.
  7. 7. Iscan Y, Aygun N, Sormaz IC, et al. Is craniocaudal dissection of recurrent laryngeal nerve safer than lateral approach: a prospective randomized study comparing both techniques by using continuous intraoperative nerve monitoring. Ann Surg Treat Res. 2022;103:205-216.
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Details

Primary Language

English

Subjects

General Surgery

Journal Section

Research Article

Publication Date

June 30, 2024

Submission Date

August 27, 2023

Acceptance Date

September 15, 2023

Published in Issue

Year 2023 Volume: 76 Number: 3

APA
Konca, C., & Elhan, A. H. (2024). The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 76(3), 244-251. https://doi.org/10.4274/atfm.galenos.2023.53765
AMA
1.Konca C, Elhan AH. The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024;76(3):244-251. doi:10.4274/atfm.galenos.2023.53765
Chicago
Konca, Can, and Atilla Halil Elhan. 2024. “The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76 (3): 244-51. https://doi.org/10.4274/atfm.galenos.2023.53765.
EndNote
Konca C, Elhan AH (June 1, 2024) The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76 3 244–251.
IEEE
[1]C. Konca and A. H. Elhan, “The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 76, no. 3, pp. 244–251, June 2024, doi: 10.4274/atfm.galenos.2023.53765.
ISNAD
Konca, Can - Elhan, Atilla Halil. “The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76/3 (June 1, 2024): 244-251. https://doi.org/10.4274/atfm.galenos.2023.53765.
JAMA
1.Konca C, Elhan AH. The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024;76:244–251.
MLA
Konca, Can, and Atilla Halil Elhan. “The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 76, no. 3, June 2024, pp. 244-51, doi:10.4274/atfm.galenos.2023.53765.
Vancouver
1.Can Konca, Atilla Halil Elhan. The Role of Clinical Factors in the Development of Loss of Signal During Thyroid Surgery. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024 Jun. 1;76(3):244-51. doi:10.4274/atfm.galenos.2023.53765