Research Article

Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses

Volume: 76 Number: 3 June 30, 2024
TR EN

Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses

Abstract

Objectives: In the study, morphometric measurements of anogenital distance, penis and clitoris dimensions were taken in female and male fetuses. In this way, it is aimed to contribute to the determination of antenatal period standards related to the subject. Materials and Methods: Fifty-five fetuses were included in the study. The anogenital distance was measured as the anus midline-posterior fourchette in girls, and the anus midline-posterior scrotal raphe in boys. Clitoris length and clitoral glans width were measured in female fetuses. Penis (glans) width and penis length were measured in male fetuses. Results: Of the 55 fetuses, 29 were female, 26 were male. Anogenital distance values were found to be significantly higher in male fetuses in both second and third trimesters compared to female fetuses (p=0.031). While a significant relationship was found between anogenital distance and phallus length values in male fetuses, no significant relationship was found in female fetuses (p<0.001), (p=0.212). In the second trimester, values of phallus length less than 5.58 mm and phallus width less than 4.55 mm are associated with female gender. In the third trimester, phallus length less than 4.79 mm and phallus width less than 5.08 mm were found to be associated with female gender (p<0.0001), (p=0.0003). Conclusion: It is thought that the reference values determined in the study regarding the phallus dimensions and the relationship of these values with the anogenital distance may contribute to the issues of deviation from normal and sex determination in the antenatal period.

Keywords

Ethical Statement

Araştırmanın yapıldığı Mersin Üniversitesi Tıp Fakültesi Klinik Araştırmalar Etik Kurulu araştırmayı onayladı (2023/195).

References

  1. 1. Odeh M, Ophir E, Bornstein J. Hypospadias mimicking female genitalia on early second trimester sonographic examination. J Clin Ultrasound. 2008;36:581-583.
  2. 2. Romano-Riquer SP, Hernández-Avila M, Gladen BC, et al. Reliability and determinants of anogenital distance and penis dimensions in male newborns from Chiapas, Mexico. Paediatr Perinat Epidemiol. 2007;21:219-228.
  3. 3. İsbir C, Elvan Ö, Taşkınlar H, et al. Assessment of clitoral anatomy in human fetuses. Surg Radiol Anat. 2020;42:453-459.
  4. 4. Taşkınlar H, Elvan Ö, İsbir C, et al. Anogenital distance and anal position index in cadaveric human fetuses. Anat Sci Int. 2023;98:155-163.
  5. 5. Leihy MW, Shaw G, Wilson JD, et al. Development of the penile urethra in the tammar wallaby. Sex Dev. 2011;5:241-249.
  6. 6. Butler CM, Shaw G, Renfree MB. Development of the penis and clitoris in the tammar wallaby, Macropus eugenii. Anat Embryol (Berl). 1999;199:451-457.
  7. 7. Zimmer EZ, Blazer S, Blumenfeld Z, et al. Fetal transient clitoromegaly and transient hypertrophy of the labia minora in early and mid pregnancy. J Ultrasound Med. 2012;31:409-415.
  8. 8. Efrat Z, Akinfenwa OO, Nicolaides KH. First-trimester determination of fetal gender by ultrasound. Ultrasound Obstet Gynecol. 1999;13:305-307.

Details

Primary Language

English

Subjects

Pediatric Surgery

Journal Section

Research Article

Publication Date

June 30, 2024

Submission Date

August 14, 2023

Acceptance Date

September 10, 2023

Published in Issue

Year 2023 Volume: 76 Number: 3

APA
İsbir, C., Elvan, Ö., Çolak, Ş., Bobuş Örs, A., & Naycı, A. (2024). Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 76(3), 252-257. https://doi.org/10.4274/atfm.galenos.2023.47704
AMA
1.İsbir C, Elvan Ö, Çolak Ş, Bobuş Örs A, Naycı A. Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024;76(3):252-257. doi:10.4274/atfm.galenos.2023.47704
Chicago
İsbir, Caner, Özlem Elvan, Şener Çolak, Alev Bobuş Örs, and Ali Naycı. 2024. “Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76 (3): 252-57. https://doi.org/10.4274/atfm.galenos.2023.47704.
EndNote
İsbir C, Elvan Ö, Çolak Ş, Bobuş Örs A, Naycı A (June 1, 2024) Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76 3 252–257.
IEEE
[1]C. İsbir, Ö. Elvan, Ş. Çolak, A. Bobuş Örs, and A. Naycı, “Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 76, no. 3, pp. 252–257, June 2024, doi: 10.4274/atfm.galenos.2023.47704.
ISNAD
İsbir, Caner - Elvan, Özlem - Çolak, Şener - Bobuş Örs, Alev - Naycı, Ali. “Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 76/3 (June 1, 2024): 252-257. https://doi.org/10.4274/atfm.galenos.2023.47704.
JAMA
1.İsbir C, Elvan Ö, Çolak Ş, Bobuş Örs A, Naycı A. Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024;76:252–257.
MLA
İsbir, Caner, et al. “Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 76, no. 3, June 2024, pp. 252-7, doi:10.4274/atfm.galenos.2023.47704.
Vancouver
1.Caner İsbir, Özlem Elvan, Şener Çolak, Alev Bobuş Örs, Ali Naycı. Morphometric Examination of Anogenital Distance, Penis and Clitoris Dimensions in Human Fetuses. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2024 Jun. 1;76(3):252-7. doi:10.4274/atfm.galenos.2023.47704

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