Can the WHO Grade of Meningiomas be Predicted with MRI Parameters?
Abstract
Objectives: MRI features of intracranial meningiomas may guide in terms of invasion and histopathological grades. The aim of this study is to
evaluate the MRI features of meningiomas with dural invasion and grade 1 and 2 menengiomas.
Materials and Methods: Seventy patients with preoperative MRI included to the study. WHO grades, precence of dura invasion, size, contact angle
with dura, contact surface lenght, relationship with sutures, diffusion and apparent diffusion coefficient (ADC) values, presence of peritumoral
edema, enhancement, contours and adjacent bone changes were evaluated retrospectively. Patients were divided into groups in terms of presence
of histopathological dura invasion and WHO grades. Histopathological features and MRI findings were compared between the groups.
Results: For WHO grades and MRI findings there were no statistically significant difference between meningiomas with and without dura invasion
(p>0.05). Percentages of presence of the following parameters were significantly higher in grade 2 meningiomas: Diffusion restriction (p=0.038),
localisation near a suture (p=0.010), peritumoral edema (p=0.006), heterogenous enhancement (p=0.027), lobulated contour of parenchymal surface
(p=0.002) and adjacent bone scalloping (p=0.029). Anteroposterior (p=0.003) and craniocaudal (p=0.047) lenght of lesions, contact surface lenght
(p=0.015) and mean age (p=0,030) were significantly higher in grade 2 meningiomas.
Keywords
Meningeal Neoplasms, Intracranial Meningioma, Magnetic Resonance Imaging
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