Toplum Kökenli Pnömoniyi COVID-19 Pnömonisinden Ayırmak Mümkün Mü?
Abstract
Objectives: Coronavirus disease-2019 (COVID-19) caused a pandemic, which has been going on for about 1 year. How long the pandemic will continue remains uncertain. Determining the etiology of pneumonia is the most important point for the treatment approach. In this study, it was aimed to determine the parameters that might be useful in the differentiation of community-acquired pneumonia (CAP) from COVID-19 pneumonia.
Materials and Methods: CAP group consisted of 53 people who applied to the infectious diseases polyclinic and chest diseases polyclinic between 01.12.2019 and 30.01.2020 in our country, including the periods when the incidence of CAP increased and influenza peaked, and were hospitalized
after being diagnosed with pneumonia. For the COVID-19 pneumonia group, 37 patients with Severe Acute Respiratory Syndrome-Coronavirus-2 detected by polymerase chain reaction from the combined nasal throat swab and with computed tomography showing lesions consistent with COVID-19 were included.
Results: Age, leukocyte count, neutrophil count, monocyte count and C-reactive protein (CRP) were significantly higher in pneumonia patients in the CAP group. In receiver operating characteristic analysis, positive predictive value of age CRP monocyte count formula was 0.83 and negative predictive value was 0.75.
Conclusion: The age difference between the groups was used in different studies on the etiology of pneumonia. It has been thought that the detection of monocytes in the tissues in postmortem studies in COVID-19 pneumonia may be due to consumption. Higher CRP detection in CAP compared to covid pneumonia was found to be similar to the literature. Our study has shown that the formulation containing monocytes, CRP and age factors, which were found to be statistically significantly different, is suitable for use in diagnostic differentiation.
Keywords
Community-Acquired Pneumonia, COVID-19, Monocyte
Ethical Statement
Ethics Committee Approval: Our study has been approved by Düzce University Local Ethical Commission with a registiration number of 2020/150.
Informed Consent: Patient consent was not obtained for our retrospective study. Peer-review: Externally peer-reviewed.
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